Fluconazole Resistance
Mostrando 25-36 de 266 artigos, teses e dissertações.
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25. Fluconazole and amphotericin-B resistance are associated with increased catalase and superoxide dismutase activity in Candida albicans and Candida dubliniensis
Introduction Candida dubliniensis, a new species of Candida that has been recovered from several sites in healthy people, has been associated with recurrent episodes of oral candidiasis in AIDS and HIV-positive patients. This species is closely related to C. albicans. The enzymatic activity of C. dubliniensis in response to oxidative stress is of interest f
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-12
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26. Environmental isolation, biochemical identification, and antifungal drug susceptibility of Cryptococcus species
Introduction The incidence of opportunistic fungal infections has increased in recent years and is considered an important public health problem. Among systemic and opportunistic mycoses, cryptococcosis is distinguished by its clinical importance due to the increased risk of infection in individuals infected by human immunodeficiency virus. Methods To det
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-12
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27. Chloroquine sensitizes biofilms of Candida albicans to antifungal azoles
Biofilms formed by Candida albicans, a human pathogen, are known to be resistant to different antifungal agents. Novel strategies to combat the biofilm associated Candida infections like multiple drug therapy are being explored. In this study, potential of chloroquine to be a partner drug in combination with four antifungal agents, namely fluconazole, vorico
Braz J Infect Dis. Publicado em: 2013-08
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28. Historical trends in the epidemiology of candidaemia: analysis of an 11-year period in a tertiary care hospital in Brazil
Candida species are an important cause of bloodstream infections (BSI). To evaluate the epidemiological, clinical and microbiological aspects of two cohorts {1994-1999 [period 1 (P1) ]; 2000-2004 [period 2 (P2) ]} of candidaemic patients, we performed a retrospective analysis from a laboratory-based survey. A total of 388 candidaemias were identified, with
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-05
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29. ATIVIDADE DAS EQUINOCANDINAS, ANFOTERICINA B E VORICONAZOL FRENTE A ISOLADOS DE Candida glabrata SENSÍVEIS E RESISTENTES AO FLUCONAZOL / ACTIVITY OF ECHINOCANDINS, ANFOTERICIN B AND VORICONAZOLE AGAINST FLUCONAZOLE-SUSCEPTIBLE AND - RESISTANT Candida glabrata ISOLATES
O uso prolongado e indiscriminado dos azólicos nos últimos anos permitiu um rápido desenvolvimento de resistência aos fármacos nas espécies de Candida. Em Candida albicans, a resistência ao fluconazol causa resistência cruzada a outros antifúngicos e aumento na virulência, tornando o tratamento ainda mais complicado por causa das opções terapêut
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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30. The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C. glabrata has been less studied than other species. In this paper, we compared the activity of three major classes of
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-05
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31. Antifungal susceptibilities of Cryptococcus species complex isolates from AIDS and non-AIDS patients in Southeast China
Cryptococcus spp. are common causes of mycoses in immunocompromised patients. To determine the drug susceptibilities of clinical Cryptococcus spp. isolates, the characteristics of 61 clinical Cryptococcus spp. complex isolates and their antifungal susceptibilities were investigated, including 52 C. neoformans and 9 C. gattii isolates collected at Shanghai be
Brazilian Journal of Infectious Diseases. Publicado em: 2012-04
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32. Susceptibility tests of oropharyngeal Candida albicans from Egyptian patients to fluconazole determined by three methods
Candida albicans frequently cause oropharyngeal candidiasis in immunocompromised patients. As some of these isolates show resistance against azoles, the clinician is wary of initiating therapy with fluconazole (FZ) until a final susceptibility report is generated. We aimed to evaluate the efficacy of rapid flow cytometry (FCM) and disc diffusion (DD) methods
Brazilian Journal of Microbiology. Publicado em: 2012-03
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33. In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis
In the present study we used two groups of Candida dubliniensis strains: one containing fluconazole-susceptible clinical isolates and another containing fluconazole-resistant laboratory derivative from the former to examine the changes on susceptibility accompanying the development of resistance to fluconazole. Our findings confirmed the ability of C. dublin
Brazilian Journal of Infectious Diseases. Publicado em: 2012-02
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34. Comparação genotípica e fenotípica de diferentes isolados clínicos e ambientais de Rhodotorula spp. / Genotypic and phenotypic comparisons among clinical and environmental isolates of Rhodotorula spp.
Introduction: Rhodotorula spp. are yeasts widely distributed in the environment and can colonize the human body at different anatomical locations. This emerging pathogen is capable of causing superficial and invasive infections in humans whereas bloodstream infection is the most commonly described in the literature. Mainly three species have been related to
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2011
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35. Identificação e análise de mutações no gene ERG11 de isolados de Candida susceptíveis e resistentes ao fluconazol / Identification and analyses of ERG11 gene mutations from fluconazole-susceptible and fluconazole-resistant Candida isolates
Por muitos anos o fluconazol tem sido uma opção usual para tratamento de infecções por Candida. Entretanto, o uso indiscriminado desta terapia antimicótica tem favorecido o surgimento de microrganismos resistentes. A redução da afinidade da enzima alvo dos antifúngicos, 14--demetilase (ERG11p), tem sido descrita como um importante mecanismo de resist
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/05/2011
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36. Vulvovaginal candidiasis in Mato Grosso, Brazil: pregnancy status, causative species and drugs tests
Causative agent in majority of VVC is Candida albicans, but infection due to non-C. albicans is common. Use of empiric antifungal therapy in Brazil due to syndromic management of vulvovaginitis could act as risk factor for increase resistance among VVC causative agents. From Mato Grosso patients, 160 with culture-proved among 404 women who had clinical sympt
Braz. J. Microbiol.. Publicado em: 2011-12