Fat Depots
Mostrando 13-24 de 42 artigos, teses e dissertações.
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13. Preweaning food intake influences the adiposity of young adult baboons.
The hypothesis that preweaning nutrition influences adult fat cell number and adiposity was tested in baboons. Newborn baboons were fed Similac formulas with caloric densities of 40.5 kcal (underfed), 67.5 kcal (fed normally), and 94.5 kcal (overfed) per 100 g formula. From weaning (16 wk) until necropsy at 5 yr of age all baboons were fed the same diet. At
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14. Identification of four chromosomal loci determining obesity in a multifactorial mouse model.
We previously described a new mouse model for multigenic obesity, designated BSB. We now report the use of a complete linkage map approach to identify loci contributing to body fat and other traits associated with obesity in this model. Four loci exhibiting linkage with body fat, or with the weights of four different fat depots, residing on mouse chromosomes
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15. Short-Term Dynamics and Metabolic Impact of Abdominal Fat Depots After Bariatric Surgery
American Diabetes Association.
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16. Relation of Abdominal Fat Depots to Systemic Markers of Inflammation in Type 2 Diabetes
American Diabetes Association.
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17. EXTRACTION AND RELEASE OF INDIVIDUAL FREE FATTY ACIDS BY THE HEART AND FAT DEPOTS*
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18. Decreased PPARγ Expression Compromises Perigonadal-Specific Fat Deposition and Insulin Sensitivity
Mutations and polymorphisms in PPARG have been linked to adiposity and partial lipodystrophy in humans. However, how disturbances in PPARG lead to depot-specific effects on adipose tissue, as shown by the characteristic aberrant fat distribution in patients, remains unclear. By manipulating the 3′-untranslated region of the Pparg gene, we have generated mi
The Endocrine Society.
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19. RANTES release by human adipose tissue in vivo and evidence for depot-specific differences
Obesity is associated with elevated inflammatory signals from various adipose tissue depots. This study aimed to evaluate release of regulated on activation, normal T cell expressed and secreted (RANTES) by human adipose tissue in vivo and ex vivo, in reference to monocyte chemoattractant protein-1 (MCP-1) and interleukin-6 (IL-6) release. Arteriovenous diff
American Physiological Society.
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20. Regional adipocyte precursors in the female rat. Influence of ovarian factors.
A flow cytometric immunofluorescence procedure utilizing a specific antibody to rat adipose tissue lipoprotein lipase (LPL) was developed to quantify differentiated and undifferentiated preadipocytes present in the adipose tissue vascular stroma. This method is highly sensitive and specific for cells capable of synthesizing LPL in significant quantities. Pub
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21. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy
Overexpression of the nuclear form of sterol regulatory element-binding protein-1c (nSREBP-1c/ADD1) in cultured 3T3-L1 preadipocytes was shown previously to promote adipocyte differentiation. Here, we produced transgenic mice that overexpress nSREBP-1c in adipose tissue under the control of the adipocyte-specific aP2 enhancer/promoter. A syndrome with the fo
Cold Spring Harbor Laboratory Press.
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22. Effects of body fat distribution on regional lipolysis in obesity.
To determine the contribution of the major body fat depots to systemic free fatty acid (FFA) availability, palmitate ([1-14C]-palmitate) release was measured from leg (lower body) and non-leg (upper body) fat in eight upper body obese (UB Ob), six lower body obese (LB Ob), and six nonobese (Non Ob) age-matched premenopausal women in the overnight postabsorpt
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23. Regulation of forearm lipolysis in different types of obesity. In vivo evidence for adipocyte heterogeneity.
Forearm and systemic adipose tissue free fatty acid (FFA) release was measured in eight nonobese, six lower-body obese, and eight upper-body obese women under basal, hyperinsulinemic, and hypoinsulinemic conditions to determine whether forearm fat is regulated in a similar manner as whole body fat. Results: Adipose tissue palmitate release was greater from f
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24. The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size.
Adipocyte size and number were determined in 288 subjects ranging in age from 4 mo to 19 yr. The study was performed in 110 obese and 178 non-obese subjects. 4-yr, longitudinal, follow-up studies were also performed in 132 subjects. The results demonstrate that the contribution of cell number and size to the growth of the fat depot in nonobese children varie