Fas Ligand
Mostrando 1-12 de 250 artigos, teses e dissertações.
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1. Induction of apoptosis by Moutan Cortex Radicis in human gastric cancer cells through the activation of caspases and the AMPK signaling pathway
Abstract Moutan Cortex Radicis, the root bark of Paeonia × suffruticosa Andrews, Paeoniaceae, has been widely used in traditional medicine therapy. Although it has been shown to possess many pharmacological activities, the molecular mechanisms of its anti-cancer activity have not been clearly elucidated. In the present study, we investigated the pro-apoptot
Rev. bras. farmacogn.. Publicado em: 2017-06
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2. Pentoxifylline and prostaglandin E1 action on ischemia and reperfusion of small intestine tissue in rats. An immunohistochemical study
PURPOSE: To investigate the action of pentoxifylline (PTX) and prostaglandin E1 (PGE1) on ischemia and reperfusion of small intestine tissue in rats, using immunohistochemical analysis. METHODS: Thirty-five Wistar rats were distributed as follows: group A (n=10): subjected to intestinal ischemia and reperfusion for 60 min, with no drugs; group B (n=10): PTX
Acta Cir. Bras.. Publicado em: 2015-02
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3. Expression of FAS ligand in the ipsilateral and contralateral testicles of rats subjected to the torsion of the unilateral testicular cord
PURPOSE: To investigate the expression of FAS ligand (FASL) in ipsilateral and contralateral testicles of rats submitted to ischemia/reperfusion. METHODS: Wistar rats (n=21) distributed into groups control (GC), n=5, testicular exposure; ischemia (GI), (n=8), Torsion in the left testicular Cord (TCT) for three hours followed by orchiectomy without distortion
Acta Cir. Bras.. Publicado em: 2013-07
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4. Quantitative study of FAS ligand expression on gastric mucosa of rats submited to oxidative stress by Azoxymethane / Estudo quantitativo na expressão de FAS ligante pós indução de estresse oxidativo em mucosa gástrica com administração de azoximetano, em ratos
Objetivo: Estudar quantitativamente a expressão da proteína ativadora de apoptose FAS ligante (FAS-L) na mucosa gástrica de ratos submetidos à exposição ao Azoximetano (AOM). Métodos: Ratos Wistar (n=56) divididos em 2 grupos: G1, controle (n=28), e G2, AOM (n=28), recebendo injeções subcutâneas de solução salina (1 mL/Kg) ou AOM (5 mg/Kg), respe
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/11/2011
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5. Níveis plasmáticos de TNF-alfa, TRAIL e FasLigante/CD95L correlacionados com a disfunção ventricular em pacientes com cardiopatia chagásica crônica OURO PRETO 2008 / Níveis plasmáticos de TNF-alfa, TRAIL e FasLigante/CD95L correlacionados com a disfunção ventricular em pacientes com cardiopatia chagásica crônica OURO PRETO 2008
Apoptose de cardiomiócitos tem sido reportado estar envolvido na patogênese da cardiomiopatia chagásica crônica (CCC). Para determinar se a maquinaria apoptótica está correlacionada aos distúrbios arrítmicos ventriculares e funcionais na CCC, foi examinado os ligantes da superfamília do TNF (TNF-alfa, Fasligante/CD95L e TRAIL), quanto a sua capacida
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/12/2008
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6. Malignant and tuberculous pleural effusions: immunophenotypic cellular characterization
INTRODUCTION AND OBJECTIVES: Tuberculosis and cancer are the main causes of pleural effusion. Pleural involvement is associated with migration of immune cells to the pleural cavity. We sought to characterize the immunophenotype of leukocytes in the pleural effusion and peripheral blood of patients with tuberculosis or malignancy. METHODS: Thirty patients wit
Clinics. Publicado em: 2008
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7. Effect of iodide on Fas, Fas-ligand and Bcl-w mRNA expression in thyroid of NOD mice pretreated with methimazole
Nonobese diabetic (NOD) mice and a derived strain, NOD.H.2h4, have been used as a model for experimental spontaneous thyroiditis and thyroiditis induced by iodide excess after a goiter-inducing period. Some authors have proposed that iodide, given after methimazole or propylthiouracil, is capable of inducing apoptosis in thyroid cells and that anti-thyroid d
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-03
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8. Expression of CD40 ligand, interferon-gamma and Fas ligand genes in endomyocardial biopsies of human cardiac allografts: correlation with acute rejection
The purpose of the present study was to investigate the expression (mRNA) of CD40 ligand (CD40L), interferon-gamma (IFN-gamma) and Fas ligand (FasL) genes in human cardiac allografts in relation to the occurrence of acute cardiac allograft rejection as well as its possible value in predicting acute rejection. The mRNA levels were determined by a semiquantita
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-06
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9. Expression of Fas and Fas Ligand on Mouse Renal Tubular Epithelial Cells in the Generalized Shwartzman Reaction and Its Relationship to Apoptosis
Previously we reported that the consecutive injection of lipopolysaccharide (LPS) into LPS-sensitized mice for the generalized Shwartzman reaction (GSR) appeared to induce the injury of renal tubular epithelial cells via apoptosis. The aim of this study was to characterize the mechanism of renal tubular epithelial cell injury in GSR. The expression of Fas an
American Society for Microbiology.
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10. Fas ligand deficiency in HIV disease
Apoptosis is postulated to be involved as an anti-viral immune mechanism by killing infected cells before viral replication has occurred. The Fas–Fas ligand interaction is a powerful regulator of T cell apoptosis and could potentially act as a potent anti-viral immune mechanism against T cell tropic virus such as human immunodeficiency virus (HIV). We inve
The National Academy of Sciences of the USA.
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11. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
The Fas ligand is predominantly expressed in activated T lymphocytes and is one of the major effector molecules of cytotoxic T lymphocytes and natural killer cells. Previously, we found excessive apoptosis of epithelial cells and infiltrating lymphocytes expressing Fas ligand mRNA in the lung tissue of bleomycin-induced pulmonary fibrosis in mice. Here we de
American Society for Clinical Investigation.
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12. Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.
Both rheumatoid arthritis and animal models of autoimmune arthritis are characterized by hyperactivation of synovial cells and hyperplasia of the synovial membrane. The activated synovial cells produce inflammatory cytokines and degradative enzymes that lead to destruction of cartilage and bones. Effective treatment of arthritis may require elimination of mo