Factors Of Growth Of Fibroblasts
Mostrando 13-24 de 408 artigos, teses e dissertações.
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13. Influencia da matriz proteica do esmalte associada ao fator de crescimento insulina-simile sobre fibroblastos do ligamento periodontal humano
The knowledge of morphological and proliferative differences between Gingival Fibroblasts (GF) and Periodontal Ligament Fibroblast (PDL) is essential to understand the role of each cell on the homeostasis, disease process and regeneration Df the periodontium. The first objective of this study was to compare the PDL and GF morphology, proliferation rate and p
Publicado em: 2001
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14. Influencia das lectinas PHA, de Phaseolus vulgaris, WGA, de germe de trigo e jacalina, de Artocarpus integrifolia, no processo de reparação tecidual da pele de ratos
Wound healing is a complex and dynamic process, characterized by the integrated actions of different cells. Lectins are glycoproteins which can present several biological activities. Many of lectin activities may contribute to repair including increased production of cytokines, and activation of inflammatory cells and fibroblasts. The purpose of this work wa
Publicado em: 1998
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15. Replication and phenotypic expression of control and scleroderma human fibroblasts: responses to growth factors.
To explore the mechanism of increased collagen synthesis by scleroderma skin fibroblasts in vitro, control and scleroderma fibroblasts were compared in confluent monolayer cultures growth-arrested by serum deprivation; responses to optimal mitogenic doses of platelet-derived growth factor, fibroblast growth factor, epidermal growth factor and nerve growth fa
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16. Growth factors from murine sarcoma virus-transformed cells.
Murine sarcoma virus-transformed mouse fibroblasts produce polypeptide growth factors and release them into serum-free medium. These factors stimulate cells to divide in monolayer cultures and also to form colonies that grow progressively soft agar. Three major peaks of activity are seen, with apparent molecular weights of 25,000, 12,000, and 7000. The sarco
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17. Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.
An important event during wound healing is the contraction of newly formed connective tissue (granulation tissue) by fibroblasts. The role of polypeptide growth factors in the process of wound contraction was investigated by analyzing the influence of transforming growth factor beta (TGF-beta), platelet-derived growth factor on the ability of fibroblasts to
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18. Serum Factor Requirements of Normal and Simian Virus 40-Transformed 3T3 Mouse Fibroblasts
Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and tra
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19. Persistence of a reduced-collagen-producing phenotype in cultured scleroderma fibroblasts after short-term exposure to interferons.
Transient exposure to inflammation-associated, fibroblast-stimulatory factors appears to initiate fibrosis by inducing the persistently activated phenotypes displayed by fibroblast cultures derived from scleroderma skin and other fibrotic tissues. To determine whether one class of fibroblast-inhibitory factors, the interferons (IFNs), plays a role in termina
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20. Induction of ornithine decarboxylase activity by insulin and growth factors is mediated by amino acids.
The polypeptide growth factors, nerve growth factor, epidermal growth factor, and platelet-derived growth factor, as well as insulin do not induce ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17) unless a minimal concentration of an ornithine decarboxylase-inducing amino acid, such as asparagine, is present in the medium. The effects of the g
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21. Human Alveolar Macrophage Growth Factor for Fibroblasts: REGULATION AND PARTIAL CHARACTERIZATION
The number of fibroblasts composing the alveolar structures in controlled within narrow limits by a strictly modulated rate of fibroblast replication. One possible source of growth-modulating signals for alveolar fibroblasts is the alveolar macrophage, a member of the mononuclear phagocyte family of cells, which collectively are known to be important sources
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22. Fibroblast-mediated acceleration of human epithelial tumor growth in vivo.
Transformed fibroblasts coinoculated with epithelial cells accelerated the growth and shortened the latency period of human epithelial tumors in athymic mice. Addition of NbF-1 fibroblasts caused epithelial tumors to grow from five marginally tumorigenic or "nontumorigenic" (nontumor-forming) human tumor cell lines or strains: PC-3 (prostate), WH (bladder),
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23. Antitubulin agents enhance the stimulation of DNA synthesis by polypeptide growth factors in 3T3 mouse fibroblasts.
Colchicine and other antitubulin agents markedly enhanced the stimulation of DNA synthesis by combinations of various growth factors such as epidermal growth factor, insulin, fibroblast-derived growth factor, and vasopressin in serum-free cultures of several quiescent 3T3 mouse fibroblast cell lines. Enhancing effects were observed based on continuous incorp
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24. α5β1 Integrin Controls Cyclin D1 Expression by Sustaining Mitogen-activated Protein Kinase Activity in Growth Factor-treated Cells
Cyclin D1 expression is jointly regulated by growth factors and cell adhesion to the extracellular matrix in many cell types. Growth factors are thought to regulate cyclin D1 expression because they stimulate sustained extracellular signal-regulated kinase (ERK) activity. However, we show here that growth factors induce transient ERK activity when added to s
The American Society for Cell Biology.