25. Transcriptional profiling of uterine leiomyoma rats treated by a traditional herb pair, Curcumae rhizoma and Sparganii rhizoma

The aim of this study was to elucidate the concise effects of a traditional herb pair, Curcumae rhizoma-Sparganii rhizoma (CRSR), on uterine leiomyoma (UL) by analyzing transcriptional profiling. The UL rat model was made by intramuscular injection of progesterone and gavage administration of diethylstilbestrol. From 11 weeks of the establishment of the mode

Braz J Med Biol Res. Publicado em: 27/05/2019

26. Effect of orthodontic forces on levels of enzymes in gingival crevicular fluid (GCF): A systematic review

Resumo Objetivo: a aplicação da força ortodôntica libera múltiplas enzimas no fluído crevicular gengival (FCG), desencadeando a ativação, reabsorção, reversão, deposição de elementos ósseos e degradação da matriz extracelular. A presente revisão sistemática avaliou criticamente toda a evidência disponível sobre os níveis de enzimas dura

Dental Press J. Orthod.. Publicado em: 20/05/2019

27. Retinoic acid increases the effect of bone morphogenetic protein type 2 on osteogenic differentiation of human adipose-derived stem cells

Abstract Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. Objective Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 ef

J. Appl. Oral Sci.. Publicado em: 21/02/2019

28. Structural Organization of Dental Biofilm Formed in situ in the Presence of Sucrose Associated to Maltodextrin

Resumo Maltodextrinas, derivadas do amido de milho, tem sido adicionadas a alimentos industrializados combinadas à sacarose. Entretanto não estão esclarecidas as propriedades de difusão na matriz do biofilme dental e a estrutura tridimensional de biofilmes multiespécies formados na presença destes carboidratos. Portanto o objetivo deste estudo foi aval

Braz. Dent. J.. Publicado em: 2019-02

29. Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis

Aggrecanase-2 (ADAMTS5) gene is responsible for aggrecan degradation that may contribute to cartilage destruction in a mouse osteoarthritis (OA) model. We aimed to investigate the effects of ADAMTS5 gene polymorphisms on OA risk in a Chinese population. A total of 300 OA patients and 300 controls were recruited and their genotypes for ADAMTS5 gene rs226794 a

Braz J Med Biol Res. Publicado em: 10/01/2019

30. Expression of urokinase-type plasminogen activator and its receptor in squamous cell carcinoma of the oral tongue

Abstract Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) act in the proteolysis of basement membrane and extracellular matrix structures, facilitating tumor invasion. The purpose of this study was to evaluate the relationship between these proteins and clinicopathological parameters in squamous cell carcinoma of the oral tongue (SCCOT). Si

Braz. oral res.. Publicado em: 13/09/2018

31. Alterations in the expression and activity of extracellular matrix components in HPV-associated infections and diseases

Infection with human papillomaviruses is associated with a series of benign and malignant hyperproliferative diseases that impose a heavy burden on human populations. A subgroup of mucosal human papillomavirus types are associated with the majority of cervical cancers and a relevant fraction of vulvar, vaginal, anal, penile and head and neck carcinomas. Huma

Clinics. Publicado em: 06/09/2018

32. Elastin increases biofilm and extracellular matrix production of Aspergillus fumigatus

Abstract Aspergillus fumigatus is an opportunistic saprobe fungus that accounts for 90% of cases of pulmonary aspergillosis in immunosuppressed patients and is known for its angiotropism. When it reaches the respiratory tract, A. fumigatus interacts with structural components and blood vessels of the lungs, such as elastin. To understand the effect of this s

Braz. J. Microbiol.. Publicado em: 2018-09

33. Alternagin-C binding to α2β1 integrin controls matrix metalloprotease-9 and matrix metalloprotease-2 in breast tumor cells and endothelial cells

Abstract Background Matrix metalloproteinases (MMPs) are key players in tumor progression, helping tumor cells to modify their microenvironment, which allows cell migration to secondary sites. The role of integrins, adhesion receptors that connect cells to the extracellular matrix, in MMP expression and activity has been previously suggested. However, the m

J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/05/2018

34. Efecto inhibidor del dióxido de germanio sobre el biofouling del puerto de Mar del Plata

ABSTRACT Marine biofouling on any new material immersed in seawater can lead to extra costs due to increased maintenance, or/and even mechanical wear, and/or biodeterioration that require costly antifouling measures. Fouling organisms growing on immersed manmade surfaces affect hulls, piers, buoys, aquaculture and pipes mainly. Following adsorption of a cond

Matéria (Rio J.). Publicado em: 05/03/2018

35. Decellularized Bovine Articular Cartilage Matrix Reinforced by Carboxylated-SWCNT for Tissue Engineering Application

ABSTRACT Nanotubes with their unique properties have diversified mechanical and biological applications. Due to similarity of dimensions with extracellular matrix (ECM) elements, these materials are used in designing scaffolds. In this research, Carboxylated Single-Wall Carbon Nanotubes in optimization of decellularized scaffold of bovine articular cartilage

Braz. arch. biol. technol.. Publicado em: 08/01/2018

36. Decellularization of placentas: establishing a protocol

Biological biomaterials for tissue engineering purposes can be produced through tissue and/or organ decellularization. The remaining extracellular matrix (ECM) must be acellular and preserve its proteins and physical features. Placentas are organs of great interest because they are discarded after birth and present large amounts of ECM. Protocols for decellu

Braz J Med Biol Res. Publicado em: 17/11/2017