Experimental Toxicology
Mostrando 13-24 de 26 artigos, teses e dissertações.
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13. Toxicity of cyanide in swine: evaluation of perinatal effects / Toxicidade do cianeto em suínos. Avaliação dos efeitos perinatais
Cyanide and cyanogenic compounds are ubiquitous in nature and widely studied in toxicology. Long-term cyanide exposure has been associated to development of goiter, pancreatic diabetes, and several neurological diseases in humans and animals. However, the exact mechanism involved in induction of these diseases are not fully elucidated. It is believed that th
Publicado em: 2006
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14. EFEITOS DO HERBICIDA GLIFOSATE SOBRE O CRESCIMENTO, ENZIMAS DIGESTIVAS E PARÂMETROS TOXICOLÓGICOS EM PIAVAS (Leporinus sp.) / EFFECTS OF GLYPHOSATE ON GROWTH, DIGESTIVE ENZYMES AND TOXICOLOGY PARAMETERS IN PIAVAS (Leporinus sp.)
The effects of glyphosate (1.0 and 5.0 mg/L) on growth, digestive enzymes and toxicology parameters were evaluated in piavas (Leporinus sp.) after 90 days of exposure. A control group was kept in water without herbicide. Fish were fed to satiety twice a day with commercial fish pellets (38% crude protein, Purina). Water quality was kept by suction of food an
Publicado em: 2005
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15. Solanum lycocarpum St. Hil unripe fruit effects in pregnant rats and offspring: alterations in reproductive and central monoaminergic systems / Efeitos dos frutos da Solanum lycocarpum St. Hil. em ratas prenhes e sua prole durante a gestação e início da lactação: alterações na esfera reprodutiva e na atividade dos sistemas monoaminérgicos centrais
A Solanum lycocarpum St. Hil (Solanaceae) é uma planta nativa do cerrado brasileiro, cujos frutos possuem os glicoalcalóides esteroidais solasonina e solamargina. É possível que a ingestão de frutos que contenham esses glicoalcalóides possam interferir no equilíbrio do sistema endócrino. O presente estudo foi realizado com o objetivo de avaliar os po
Publicado em: 2005
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16. Efeitos na esfera reprodutiva da exposição prolongada a Solanum lycocarpum durante a puberdade de ratos / Effects on reproductive system of long-term exposition to Solanum lycocarpum during rats puberty
Solanum lycocarpum St. Hil, a toxic plant common in almost all states of Brazil, may be consumed by animals in fertile age and in natural condition. The fruits of this plant contain steroidal glycoalkaloids with steroid-like properties. Presently the reproductive effects of S. lycocarpum fruit ingestion during puberty were investigated. The dried fruits were
Publicado em: 2005
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17. Toxidade reprodutiva do diuron em ratos machos adultos / Reproductive toxicity of diuron in adult male rats
O diuron (3-(3,4-diclorofenil)-1,1-dimetilurea) é um herbicida uréico cuja DL50 oral aguda em raios é igual a 3400 mg/Kg. É muito utilizado na agricultura e seus efeitos no organismo animal ainda são pouco conhecidos, principalmente no sistema reprodutor. O objetivo deste trabalho foi avaliar o possível efeito tóxico do diuron no sistema reprodutor ma
Publicado em: 2005
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18. Reproductive toxicity of diuron in adult male rats / Toxicidade reprodutiva do diuron em ratos machos adultos
O diuron (3-(3,4-diclorofenil)- Ll-dimetilurea) é um herbicida uréico cuja DL:io oral aguda em ratos é igual a 3400 mg/Kg. É muito utilizado na agricultura e seus efeitos no organismo animal ainda são pouco conhecidos. principalmente no sistema reprodutor. O objetivo dcste trabalho foi avaliar o possível efeito tóxico do diuron no sistema reprodutor m
Publicado em: 2005
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19. Desenvolvimento reprodutivo de ratos machos expostos ao fenvalerato in utero e lactação / Reproductive development of male rats exposed to fenvalerate in utero and lactation
Fenvalerate is a synthetic pyrethroid insecticide used in agriculture, cattle raising and in the control of domestic insects, and its reproductive effects are little-known.Some studies already have proposed that fenvalerate is an endocrine disruptor, acting as an environmentalestrogen. Studies done with rats exposed to some pyrethroids showed reduction of sp
Publicado em: 2005
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20. Avaliação dos efeitos tóxicos do cianeto e do tiocianato no período perinatal. Estudo em ratos / Evaluation of toxic effects of cyanide and thiocyanate during perinatal period. Study in rats
The aim of the present study was to determinate the toxic effects of long-term exposure to KCN and KSCN in rats, during perinatal period. Initially, it was achieved the toxicokinetics study of the thiocyanate in female rats, in three different physiological states: estrogenic, gestation and lactation. These animals received, per os, in the drinking water or
Publicado em: 2004
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21. Experimental Pharmacology and Toxicology
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22. Clinical and Experimental Toxicology of Organophosphates and Carbamates
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23. The Assessment of Electroencephalographic Changes and Memory Disturbances in Acute Intoxications with Industrial Poisons
A report is given of the results of the electroencephalogram (EEG) and of an experimental memory examination in a group of 22 cases of acute carbon monoxide and solvents poisoning of varying severity. An abnormal EEG recording, most often in the form of theta activity 5-6 sec., was found in 12 patients; memory disturbances were found in 13 cases. There was c
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24. Predicting chemically induced duodenal ulcer and adrenal necrosis with classification trees.
Binary tree-structured statistical classification algorithms and properties of 56 model alkyl nucleophiles were brought to bear on two problems of experimental pharmacology and toxicology. Each rat of a learning sample of 745 was administered one compound and autopsied to determine the presence of duodenal ulcer or adrenal hemorrhagic necrosis. The cited sta