Experimental Periodontitis
Mostrando 1-12 de 95 artigos, teses e dissertações.
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1. Evaluation of the effect of topical and systemic ozone application in periodontitis: an experimental study in rats
Abstract Objective: The goal of the present study was to determine the effect of systemic and topical ozone application on alveolar bone loss (ABL) by evaluating the effect of Hypoxia-inducible factor −1 alpha (HIF-1-α) and receptor activator of NF-kB ligand (RANKL)-positive cells on histopathological and immunohistochemical changes in a rat periodontiti
J. Appl. Oral Sci.. Publicado em: 28/11/2019
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2. Effects of 1,25-dihydroxyvitamin D3 on experimental periodontitis and AhR/NF-κB/NLRP3 inflammasome pathway in a mouse model
Abstract Vitamin D has been known to have important regulatory functions in inflammation and immune response and shows inhibitory effects on experimental periodontitis in animal models. However, the potential mechanism has yet to be clarified. Recent studies have highlighted Aryl hydrocarbon receptor (AhR) and its downstream signaling as a crucial regulator
J. Appl. Oral Sci.. Publicado em: 04/11/2019
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3. Comparison of apical periodontitis repair in endodontic treatment with calcium hydroxide-dressing and aPDT
Abstract This study evaluated the effect of antimicrobial photodynamic therapy (aPDT) on the endodontic treatment of apical periodontitis (AP). AP was induced in 48 premolars of 6 dogs. After biomechanical preparation, the teeth were divided into 4 groups: Calcium-Hydroxide (CH)/120d and CH/180d: root canals filled with CH-based dressing for 15 days before o
Braz. oral res.. Publicado em: 26/09/2019
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4. Effect of avocado/soybean unsaponifiables on periodontal repair in rats with arthritis and induced periodontitis
Abstract Objective: This study aimed to evaluate the effect of avocado/soybean unsaponifiables (ASU) on periodontal repair in rats with induced periodontitis and arthritis. Methodology: Forty-five rats were submitted to periodontitis induction by insertion of ligatures into the upper second molars, maintained for 15 days. These animals were randomly alloca
J. Appl. Oral Sci.. Publicado em: 09/09/2019
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5. Effects of astragaloside IV on inflammation and immunity in rats with experimental periodontitis
Abstract: This study aimed to investigate the effects of astragaloside IV (AsIV) on inflammation and immunity in rats with experimental periodontitis. Periodontitis was established in 48 Wistar rats, which were then randomly divided into model and 10, 20 and 40 mg/kg AsIV groups, with 12 rats in each group. The latter 3 groups were treated with AsIV at doses
Braz. oral res.. Publicado em: 25/04/2019
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6. Effects of Selective Versus Non-Selective COX-2 Inhibition on Experimental Periodontitis
Resumo No presente estudo nós comparamos os efeitos de um inibidor seletivo da COX-2 (etoricoxibe) com um anti-inflamatório não esteroidal não seletivo (AINE) (diclofenaco de potássio) no processo inflamatório e perda óssea alveolar em modelo de periodontite experimental. Noventa ratos Holtzman machos (250 g) foram randomizados em quatro grupos experi
Braz. Dent. J.. Publicado em: 04/04/2019
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7. BONE TISSUE BEHAVIOR OF RATS WITH EXPERIMENTAL PERIODONTITIS SUBJECTED TO PHYSICAL EXERCISE
RESUMO Introdução: É possível que a atividade física proteja o periodonto por atenuar a resposta inflamatória excessiva do indivíduo. Há algumas evidências em estudos longitudinais e um estudo prospectivo que demonstram que adultos fisicamente ativos têm tido diminuição do risco de periodontite. Até o momento, nenhum estudo explorou conjuntamen
Rev Bras Med Esporte. Publicado em: 2019-04
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8. Radiographic and Immunohistochemical Evaluation of Root Canal Treatment Using Different Irrigation Systems
Resumo O objetivo deste estudo foi avaliar o reparo periapical e a síntese de mediadores inflamatórios após tratamento endodôntico em dentes de cães com lesão periapical, em sessão única, utilizando diferentes protocolos de irrigação. Lesões periapicais foram induzidas experimentalmente em dentes de cães e aleatoriamente divididas em 4 grupos: G1
Braz. Dent. J.. Publicado em: 2019-03
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9. Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model
Abstract Objective The aim of this study was to evaluate the effects of gliclazide on oxidative stress, inflammation, and bone loss in an experimental periodontal disease model. Material and Methods Male albino Wistar rats were divided into no ligature, ligature, and ligature with 1, 5, and 10 mg/kg gliclazide groups. Maxillae were fixed and scanned usin
J. Appl. Oral Sci.. Publicado em: 21/02/2019
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10. Evaluating clinical and laboratory effects of ozone in non-surgical periodontal treatment: a randomized controlled trial
Abstract Objective: This study aims to evaluate the clinical and biochemical (oxidative stress and pro-inflammatory mediators) effects of the gaseous ozone use accompanied by scaling and root planning (SRP) in periodontal treatment. Material and Methods: The study population consisted of 40 patients with chronic periodontitis (CP) randomly sorted into two
J. Appl. Oral Sci.. Publicado em: 14/01/2019
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11. The role of potassium channels in the endothelial dysfunction induced by periodontitis
Abstract Objective: Periodontitis is associated with endothelial dysfunction, which is clinically characterized by a reduction in endothelium-dependent relaxation. However, we have previously shown that impairment in endothelium-dependent relaxation is transient. Therefore, we evaluated which mediators are involved in endothelium-dependent relaxation recove
J. Appl. Oral Sci.. Publicado em: 04/10/2018
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12. Effects of diode laser application on inflammation and mpo in periodontal tissues in a rat model
Abstract Objective In this study, we aimed to histologically and immunologically evaluate the effect of diode laser treatment when applied adjunctive to scaling and root planing (SRP) in an experimental periodontitis model. Materials and methods We used Wistar-Albino rats (n=60) with average weight of 230 g. Experimental periodontitis was induced by liga
J. Appl. Oral Sci.. Publicado em: 16/07/2018