Exoantigens
Mostrando 1-12 de 31 artigos, teses e dissertações.
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1. Leptomonas seymouri and Crithidia fasciculata exoantigens can discriminate human cases of visceral leishmaniasis from American tegumentary leishmaniasis ones
ABSTRACT Exoantigens (exo) from Leptomonas seymouri and Crithidia fasciculata were used in an enzyme linked immunosorbent assay (ELISA), showing 100% reactivity with sera from visceral leishmaniasis (VL) cases, and no reactivity with American tegumentary leishmaniasis (ATL) ones. Our results have indicated that these exoantigens can be applied in the discrim
Rev. Inst. Med. trop. S. Paulo. Publicado em: 03/04/2017
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2. Field validation of a Leishmania (Leishmania) mexicana exo-antigens ELISA for diagnosing tegumentary leishmaniasis in regions of Leishmania (Viannia) predominance
Background: Several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via secretion, excretion and metabolism are more specific than are antigens released by the lysis of Leishmaniaparasites. Such antigens are known as exo-antigens (exo-Ag) and are formed from product
Braz J Infect Dis. Publicado em: 2015-06
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3. Evaluation of excreted-secreted antigens of L. (L.) amazonensis, L. (V.) braziliensis and L. (L.) chagasi in immunodiagnosis of human and dog Visceral leishmaniasis. / Avaliação imunodiagnóstica de antígenos excretados-secretados de L. (L.) amazonensis, L. (V.) braziliensis e L.(L.) chagasi na Leishmaniose visceral humana e canina.
A Leishmaniose visceral é um problema que cresce no Estado de São Paulo afetando o homem e o cão. Os exoantígenos da membrana das leishmanias são liberados no meio de cultura. Os exoantígenos são importantes na indução da imunidade mediada pelas células T e B estimulando a produção elevada de anticorpos. Realizamos uma avaliação comparativa por
Publicado em: 2009
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4. Analysis of Paracoccidioides brasiliensis exoantigens stability
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2006
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5. Detoxified exoantigens and phosphatidylinositol derivatives inhibit tumor necrosis factor induction by malarial exoantigens.
We have previously shown that malaria parasites liberate exoantigens which, through a phospholipid component, stimulate mouse macrophages to secrete tumor necrosis factor (TNF), which are toxic to D-galactosamine-sensitized mice, and which therefore might be involved in pathology. Plasmodium yoelii exoantigens detoxified by dephosphorylation or digestion wit
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6. Serological relationship of tumor necrosis factor-inducing exoantigens of Plasmodium falciparum and Plasmodium vivax.
Exoantigens of Plasmodium vivax-parasitized erythrocytes stimulated macrophages to secrete tumor necrosis factor, and antisera raised against the exoantigens inhibited this secretion. The antisera also inhibited the activity of Plasmodium falciparum and Plasmodium yoelii exoantigens, and conversely, antisera against the latter cross-reacted with the exoantig
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7. Cellular and humoral immune responses induced in cattle by vaccination with Babesia divergens culture-derived exoantigens correlate with protection.
Previous results with the Babesia divergens gerbil vaccination model were extended in studies with cattle. Two calves were vaccinated with culture-derived B. divergens exoantigens, and two others were treated with control supernatant; both preparations were adjuvanted with Quil-A saponin. A parasite-specific humoral response was observed after the first vacc
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8. Comparative antigenic studies of species of Basidiobolus and other medically important fungi.
An immunodiffusion technique was used to evaluate the antigenic relationship of various pathogenic and saprobic Basidiobolus spp., Conidiobolus spp., isolates of the order Mucorales, and several other medically important nonzygomycetous fungi. The antiserum to Basidiobolus haptosporus shared two lines of identity, designated inner (N) and outer (Y), when tes
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9. Exoantigen test for identification of Petriellidium boydii cultures.
Cultures of Petriellidium boydii were serologically identified by detection of their exoantigens with an immunodiffusion procedure. The technique, which is specific and sensitive, allowed the rapid identification and differentiation of 12 isolates of P. boydii from numerous other morphologically similar Hyphomycetes. The antigen-antiserum reference system an
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10. Two soluble antigens of Plasmodium falciparum induce tumor necrosis factor release from macrophages.
The production of cytokines such as tumor necrosis factor (TNF) may contribute to the pathology of malaria. We showed previously that crude preparations of heat-stable exoantigens from parasite cultures induce the release of TNF in vitro and in vivo. When separated from the culture medium by affinity chromatography, in which immune immunoglobulin G was used
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11. Analysis of Immune Responses of Different Hosts to Babesia divergens Isolates from Different Geographic Areas and Capacity of Culture-Derived Exoantigens To Induce Efficient Cross-Protection
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12. Induction of protective immunity to Plasmodium falciparum in Saimiri sciureus monkeys with partially purified exoantigens.
Soluble Plasmodium falciparum exoantigens in crude culture supernatant fluids induced protective immunity against experimental falciparum malaria in Bolivian Saimiri sciureus monkeys. Susceptible squirrel monkeys were vaccinated with an aluminum hydroxide-fortified fraction purified from culture supernatants of P. falciparum Indochina I and Geneve/SGE-1 by c