Estrogenic Receptors
Mostrando 1-12 de 22 artigos, teses e dissertações.
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1. Gene expression of estrogen and oxytocin receptors in the uterus of pregnant and parturient bitches
In the canine species, the precise mechanisms of pregnancy maintenance and the initiation of parturition are not completely understood. The expression of genes encoding the receptors for estrogen (ERα mRNA) and oxytocin (OTR mRNA) was studied in the endometrium and myometrium during pregnancy and parturition in dogs. Real-time PCR was performed to quantify
Braz J Med Biol Res. Publicado em: 13/02/2015
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2. Histological investigation of the effect of soybean (Glycine max) extracts on the collagen layer and estrogen receptors in the skin of female rats
OBJECTIVES: The purpose of this study was to analyze the effects of soybean extracts obtained using different extraction methods on the skin of female rats. METHOD: A total of 64 female Sprague-Dawley rats were divided in
Clinics. Publicado em: 2014
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3. Densidade mamária e polimorfismo do gene do receptor estrogênico em mulheres com mamas densas após a menopausa / Breast density and polymorphism of the estrogen receptor gene in women with hight breast density after menopause
Introdução: Polimorfismo é variação genética de ocorrência habitual na população em geral, encontrado em frequência superior a 1%. Há vários polimorfismos conhecidos no gene do receptor estrogênico alfa, alguns dos quais podem modificar a função do receptor e a ação dos estrogênios. Associação de polimorfismos no gene do receptor estrogê
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/10/2012
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4. EFEITO DA GENISTEÍNA NA FUNCIONALIDADE DE MACRÓFAGOS: UM ESTUDO COMPARATIVO ENTRE RATOS MACHOS E FÊMEAS
Genistein has estrogenic activity and can bind to estrogen receptors (ER), so it is considered a phytoestrogen. ER have been reported in macrophages and in that sense, the estrogens modulate immune responses. Despite the sexual dimorphism of the immune responses in females and males is well established, there are few studies that elucidate the role of bioact
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/04/2011
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5. Differential binding with ERα and ERβ of the phytoestrogen-rich plant Pueraria mirifica
Variations in the estrogenic activity of the phytoestrogen-rich plant, Pueraria mirifica, were determined with yeast estrogen screen (YES) consisting of human estrogen receptors (hER) hERα and hERβ and human transcriptional intermediary factor 2 (hTIF2) or human steroid receptor coactivator 1 (hSRC1), respectively, together with the β-galactosidase expres
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-02
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6. Desenvolvimento da próstata masculina e feminina do gerbilo da Mongólia submetido à exposição no período embriofetal e pós-natal de etinilestradiol / Development of male and female prostate of the Mongolian gerbil submitted to the exposure embryofetal period and postnatal ethinylestradiol
In males, prostatic morphogenesis is an event controlled by androgens, which act directly via paracrine factors secreted by the mesenchyme. In females, the embryological development of the prostate appears to occur in environment low levels of steroid hormones, but the presence of these hormones in the adult life induces differentiation and secretory activit
Publicado em: 2010
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7. Imprinting estrogenico : efeito sobre a expressão do receptor de androgeno no hipotalamo de ratos Wistar / Effects of estrogenic imprinting on the androgen receptor expression in the hypothalamus of Wistar rats
In male rats, complete reproductive function is critically dependent on adequate estrogen action at different levels of the hypothalamic-pituitary-gonadal axis. The administration of high doses during the period of sexual differentiation results in irreversible alterati ns in the male reproductive system. In brief, the estrogens have anti-androgenic effects
Publicado em: 2008
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8. REGULAÇÃO DA EXPRESSÃO DO RECEPTOR AT2 E EFEITO DA ANGIOTENSINA II SOBRE A EXPRESSÃO DE GENES ENVOLVIDOS NO DESENVOLVIMENTO FOLICULAR E OVULAÇÃO EM CÉLULAS DA GRANULOSA DE BOVINOS / REGULATION OF AT2 RECEPTORS IN BOVINE GRANULOSA CELLS, AND EFFECTS OF ANGIOTENSIN II ON GENES INVOLVED IN FOLLICLE DEVELOPMENT AND OVULATION
The objective of this study was to investigate the factors controling the expression of angiotensin II (AngII) receptors and to determine the physiological role of AngII in granulosa cells. The AGTR2 receptor was localized in granulosa (and theca) cells from follicles of different sizes. Bovine ovaries were collected at a local abattoir and small follicles (
Publicado em: 2007
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9. Análise molecular do gene FOXL2 em mulher com síndrome blefarofimose ptose epicanto inverso com falência ovariana prematura
Premature ovarian failure (POF) is a disorder with very important repercussions for woman life, either regarding the end of reproductive lifespan or the consequent estrogenic hormonal deficiency. The number of POF causes is quite a lot, including infectious diseases as well as immunologyc, iatrogenic and genetic disorders. Since the advances in past decades
Publicado em: 2007
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10. Early onset of puberty and early ovarian failure in CYP7B1 knockout mice
CYP7B1 is the enzyme responsible for hydroxylation and termination of the estrogenic actions of the androgen metabolite, 5α-androstane-3β, 17β-diol (3βAdiol). 3βAdiol is estrogenic in ERα or ERβ positive cells only if they do not express CYP7B1. In this study we show that female CYP7B1–/– mice experience early onset of growth of the uterus and mam
National Academy of Sciences.
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11. Isolated uterine nuclei and cytosol receptors of aged rats exhibit impaired estrogenic stimulation of RNA polymerase II.
An in vitro cell-free system of uterine nuclei and cytosol receptors has been used to analyze the effects of aging on estrogen stimulation of RNA polymerase II activity. By using fixed concentrations of nuclei and cytoplasmic receptor--estrogen complexes (R-E2), it was found that mature nuclei are 3 times more efficient (155% vs. 57%) than old ones for stimu
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12. Estrogenic activity of the insecticide chlordecone (Kepone) and interaction with uterine estrogen receptors.
The chlorinated insecticide chlordecone (Kepone) interacts with the estrogen receptor system in the rat uterus in vitro and in vivo. It competes with estradiol for binding to the cytoplasmic receptor in vitro and also induces nuclear accumulation of estrogen receptor sites in uteri in vitro. When injected into immature rats, chlordecone translocates estrogen