1. Qual o tratamento medicamentoso para tremor essencial?

O tratamento medicamentoso deve ser considerado quando o tremor provocar qualquer nível de limitação funcional ou desconforto no paciente, como por exemplo, constrangimento em situações sociais. Propranolol e primidona são os medicamentos de primeira escolha.

A dose inicial do Propranolol é de 20 mg, três vezes ao dia, podendo ser aumentado

Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023

2. Qual a melhor opção terapêutica para idosos com tremor essencial?

Pequenos ensaios clínicos randomizados observaram que o propranolol melhorou escores clínicos, amplitude do tremor e auto-avaliação da severidade dos sintomas quando comparado com placebo, sendo portanto uma boa alternativa na população idosa, desde que o paciente não apresente contra-indicações (1).

O fenobarbital e a primidona podem melho

Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023

3. A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans

Abstract XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we create a germline-specific xrn-2 conditional mutant and p

Genetics and Molecular Biology. Publicado em: 2023

4. Self-regulation in youth with bipolar disorder

Objectives: To examine the composition of self-regulation in pediatric bipolar disorder (PBD) through the relationship between executive functions, emotion processing, and family environmental factors. Methods: 58 participants (36 with PBD and 22 controls), ages 12-17, were assessed using the Barratt Impulsiveness Scale (BIS), Conners’ Continuous Performa

Brazilian Journal of Psychiatry. Publicado em: 2023

5. Compliance with Enhanced Recovery After Surgery (ERAS) protocol recommendations for bariatric surgery in an obesity treatment center

Abstract Introduction The higher risk of perioperative complications associated with obesity has made anesthesiologists increasingly concerned with the management of obese patients. Measures that improve bariatric surgery patient safety have become essential. The implementation of ERAS protocols in several surgical specialties has made it possible to achiev

Brazilian Journal of Anesthesiology. Publicado em: 2023

6. How Much do the Environmental Conditions Interfere with the Essential Oils of Eugenia spp. L. (Myrtaceae)?

Eugenia is the largest neotropical genus in the Myrtaceae family. The genus has a wide geographical distribution, occurring from Mexico to Argentina. Eugenia species are rich in essential oils. Essential oils have applications in perfumery, cosmetics, food, pesticides and medicines. Several factors can influence the chemical composition and yield of essentia

Journal of the Brazilian Chemical Society. Publicado em: 2022

7. Quality Control for Lignin and Gelatin Microcapsules Loaded with Orange Essential Oil

Sustainable natural product-based microstructured systems and biopolymers are strong candidates for use in crop protection. Lignin and gelatin microcapsules loaded with orange essential oil were developed with spray-drying in order to enhance its potential. We evaluated the microparticle controlled release mechanisms, biological effects, structural and therm

Journal of the Brazilian Chemical Society. Publicado em: 2022

8. How to Take Care of Your Body: Not an Obvious Insight, but an Essential School Lesson

International Journal of Cardiovascular Sciences. Publicado em: 2022

9. Is the 9-item Patient Health Questionnaire sufficiently sensitive to detect clinical risk of suicide in essential workers seeking emotional support during the COVID-19 pandemic?

Brazilian Journal of Psychiatry. Publicado em: 2022

10. Molecular Docking in silico Analysis of Brazilian Essential Oils Against Host Targets and SARS-CoV-2 Proteins

The inhibitory activity of thirty-one sesquiterpenes identified from Brazilian essential oils (Copaifera langsdorffii Desf., Croton cajucara Benth. and Siparuna guianensis Aublet.) were analyzed by in silico molecular docking. The compounds were characterized by gas chromatography-mass spectrometry (GC-MS) and gas chromatography with flame-ionization detecti

Journal of the Brazilian Chemical Society. Publicado em: 2022

11. Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying

Croton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low aqueous solubility prevent its technological application. This study aimed to prepare and characterize the Croton zehntneri essential oil (CZEO) complexed with β-cyclodextrin (β-CD), and to evaluate ant

Journal of the Brazilian Chemical Society. Publicado em: 2022

12. Public Programs for Essential Medicine Access in a Small Municipality: A Cross-Sectional Analysis

Abstract Background: Public programs that provide access to essential medications have played an important role in the care of hypertensive and diabetic patients. However, access in small municipalities has been poorly studied. Objectives: To describe the sociodemographic profile and the medication and health service usage of patients with systemic arteria

International Journal of Cardiovascular Sciences. Publicado em: 2022