Esophageal Adenocarcinoma
Mostrando 13-24 de 31 artigos, teses e dissertações.
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13. A clinical evaluation of argon plasma coagulation in Barrett´s esophagus mucosal ablation therapy / Avaliação da aplicação clínica da coagulação com plasma de argônio na ablação do esôfago de Barrett
The aim of this study is to determine the effectiveness of the Argon Plasma Coagulation (APC) in ablation therapy of specialized columnar epithelium in Barrett´s esophagus. The presence of Barrett´s epithelium is considered a premalignant condition with potential development of adenocarcinoma. The incidence of esophageal adenocarcinoma has been rising for
Publicado em: 2008
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14. Over-expression of cyclooxygenase-2 in endoscopic biopsies of ectopic gastric mucosa
Ectopic gastric mucosa (EGM) is considered to be a congenital condition. Rare cases of adenocarcinoma have been described. There are no data justifying regular biopsies or follow-up. Cyclooxygenase-2 (COX-2) is a protein involved in gastrointestinal tumor development by inhibiting apoptosis and regulating angiogenesis. The aim of this prospective study was t
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-11
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15. Prevalência da expressão imunoistoquímica da proteína p21 em adenocarcinoma do esôfago
INTRODUÇÃO: No mundo ocidental, a prevalência de adenocarcinoma da junção esofagogástrica vem crescendo nas últimas décadas. Atualmente, é aceito que o adenocarcinoma do esôfago se desenvolve de uma lesão pré-maligna: esôfago de Barrett. Este carcinoma é de difícil diagnóstico nos seus estágios iniciais, o que resulta em uma mortalidade sign
Publicado em: 2007
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16. Avaliação da expressão da proteína p53 e do VEGF (Fator de Crescimento do Endotélio Vascular) em pacientes com adenocarcinoma de esôfago / Evaluation of p53 protein and VEGF (vascular Endothelial Growth Factor) expresion in patients with esophageal adenocarcinoma
O prognóstico dos pacientes com adenocarcinoma de esôfago é bastante prejudicado pelo seu diagnóstico tardio. Na tentativa de determinar fatores que possam alterar o prognóstico destes pacientes, o estudo da biologia molecular tem recebido grande importância. As mutações no gene de supressão tumoral TP53 estão entre as anormalidades genéticas mais
Publicado em: 2007
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17. Expressão imunohistoquímica do C-MYC na seqüência metaplasia-displasia-adenocarcinoma no esôfago
Introdução e Objetivos: O esôfago de Barrett (BE) desenvolve-se como conseqüência de uma agressão acentuada sobre a mucosa esofágica causada pelo refluxo gastresofágico crônico. É uma lesão precursora e exerce papel importante no desenvolvimento do adenocarcinoma esofágico (ACE). Inúmeras alterações genéticas estão presentes ao longo da tran
Publicado em: 2007
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18. Synchronous advanced gastric adenocarcinoma and advanced esophageal squamous cell carcinoma
CONTEXTO: A associação sincronicamente de cânceres do esôfago e estômago não é um achado comum, especialmente com tipos histológicos diferentes e ambos os tumores avançados. Um caso com essa associação é relatado e proposta uma terapia: gastrectomia paliativa e prótese esofágica. RELATO DE CASO: Um paciente do sexo masculino, branco, de 75 anos
Sao Paulo Medical Journal. Publicado em: 03/01/2002
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19. A novel amplicon at 8p22–23 results in overexpression of cathepsin B in esophageal adenocarcinoma
Cathepsin B (CTSB) is overexpressed in tumors of the lung, prostate, colon, breast, and stomach. However, evidence of primary genomic alterations in the CTSB gene during tumor initiation or progression has been lacking. We have found a novel amplicon at 8p22–23 that results in CTSB overexpression in esophageal adenocarcinoma. Amplified genomic NotI–HinfI
The National Academy of Sciences.
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20. Gastric juice protects against the development of esophageal adenocarcinoma in the rat.
OBJECTIVE: The authors investigate the effects of gastric juice on tumorigenesis in a rat model of esophageal adenocarcinoma. SUMMARY BACKGROUND DATA: In rats treated with the carcinogen methyl-n-amyl nitrosamine, squamous cancer of the esophagus develops in a time- and dose-dependent manner. When methyl-n-amyl nitrosamine treatment is preceded by an operati
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21. Proximal gastric cancers resected via a transabdominal-only approach. Results and comparisons to distal adenocarcinoma of the stomach.
OBJECTIVE: The purpose of this study is to compare the outcome of patients with proximal gastric cancer (PGC) treated by a transabdominal-only resection to that of patients with distal gastric cancer (DGC). SUMMARY BACKGROUND DATA: It has been suggested that PGC is inherently more aggressive than DGC. The worse survival of PGC compared with that of DGC may b
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22. Barrett's esophagus in children. Diagnosis and management.
OBJECTIVE: To determine the local prevalence and optimal therapy for children with Barrett's esophagus (BE), the authors studied children with esophageal strictures or gastroesophageal reflux (GER), or both, to diagnose BE and to follow after therapy. SUMMARY BACKGROUND DATA: Barrett's esophagus is seldom reported in children and therapeutic recommendations
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23. Endodissection of the thoracic esophagus. Technique and clinical results in transhiatal esophagectomy.
OBJECTIVE: Transhiatal esophagectomy (THE), mostly performed in patients with adenocarcinoma of the esophagus, bears the risk of damage to mediastinal structures because the physician's vision is poor during esophageal dissection. The authors report a new endoscopic technique, which enables microsurgical dissection of the esophagus under visual control, that
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24. Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway
In this case–control study with 387 White esophageal patients and 462 White controls matched to cases by age and sex, we evaluated the associations between 13 potential functional polymorphisms in eight major nucleotide excision repair (NER) genes and esophageal cancer risk. In individual single nucleotide polymorphism analysis, after adjustment for multip
Oxford University Press.