Erythrocyte Membranes
Mostrando 1-12 de 362 artigos, teses e dissertações.
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1. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers
4-Nerolidylcatechol (4-NC) is found in Pothomorphe umbellataroot extracts and is reported to have a topical protective effect against UVB radiation-induced skin damage, toxicity in melanoma cell lines, and antimalarial activity. We report a comparative study of the antioxidant activity of 4-NC and α-tocopherol against lipid peroxidation initiated by two fre
Braz J Med Biol Res. Publicado em: 06/09/2013
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2. Electron paramagnetic resonance study of lipid and protein membrane components of erythrocytes oxidized with hydrogen peroxide
Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to monitor membrane dynamic changes in erythrocytes subjected to oxidative stress with hydrogen peroxide (H2O2). The lipid spin label, 5-doxyl stearic acid, responded to dramatic reductions in membrane fluidity, which was correlated with increases in the protein content of the membran
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-06
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3. Estresse oxidativo em membranas de eritrócito avaliado por ressonância paramagnética eletrônica / Oxidative stress in erythrocyte membranes evaluated by electron spin resonance
Os efeitos do estresse oxidativo promovido pelo peróxido de hidrogênio (H2O2) e pelo 2,2-Azobis(2-metilpropanamida) dicloridrato (AAPH) nas proteınas e lipídios da membrana de eritrócito foram investigados através do teste da hemólise oxidativa, da formação do malondialde ıdo (MDA) além da espectroscopia de ressonância paramagnética elet
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/03/2010
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4. Solubilization of human erythrocyte membranes by ASB detergents
Understanding the membrane solubilization process and finding effective solubilizing agents are crucial challenges in biochemical research. Here we report results on the interaction of the novel linear alkylamido propyl dimethyl amino propanosulfonate detergents, ASB-14 and ASB-16, with human erythrocyte membranes. An estimation of the critical micelle conce
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-09
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5. Solubilização de membranas eritrocitarias : analise quantitativa do efeito hemolitico induzido por surfatantes
Surfatantes ou detergentes são compostos anfifílicos que, na presença de água, têm a característica de formar agregados micelares. Surfatantes induzem a desestruturação de outros agregados como bicamadas sendo, por isso, usados para ruptura celular ou solubilização de lipídios e proteínas de membrana. A capacidade lítica dos surfatantes resulta
Publicado em: 2006
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6. QUANTIFICATION OF REDUCED GLUTATHIONE IN HUMAN ERYTHROCYTES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-UV: VALIDATION AND APLICATION / QUANTIFICAÇÃO DA GLUTATIONA REDUZIDA EM ERITRÓCITOS HUMANOS POR CROMATOGRAFIA LÍQUIDA DE ALTA EFICIÊNCIA-UV: VALIDAÇÃO E APLICAÇÃO
Oxidative stress may be initiated by a decline in the antioxidant defence system or by an overproduction of free radicals leading to an imbalance between oxidants and antioxidants. The most significant alteration in the antioxidant defence is a decrease in reduced glutathione (GSH) concentration. GSH depletion is linked to a number of disease states; includi
Publicado em: 2005
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7. Desenvolvimento e avaliação farmacologica de formulações de liberação controlada com anestesicos locais amino-amidas ciclicos : bupivacaina, mepivacaina e ropivacaina / Development and pharmacological evaluation of drug-delivery systems for cyclic amino-amide local anesthetics: bupivacaine, mepivacaine and ropivacaine
Local anesthetics (LA) are among the different classes of pharmacological compounds used to attenuate or to eliminate pain. These drugs, which are able to reversibly block the excitation/transmission of the nerve impulse in axons have a relatively short action and a significant toxicity to the Central Nervous and Cardiovascular systems. In order to prolong t
Publicado em: 2005
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8. Elevated levels of erythrocyte-conjugated dienes indicate increased lipid peroxidation in schistosomiasis mansoni patients
Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid peroxidation. We have evaluated lipid peroxidation in 18 patients with hepatosplenic schistosomiasis mansoni previously treated with
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-07
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9. Anestésicos locais: interação com membranas de eritrócitos de sangue humano, estudada por ressonância magnética nuclear de ¹H e 31P
The literature carries many theories about the mechanism of action of local anesthetics (LA). We can highlight those focusing the direct effect of LA on the sodium channel protein and the ones that consider the interaction of anesthetic molecules with the lipid membrane phase. The interaction between local anesthetics and human erythrocyte membranes has been
Química Nova. Publicado em: 2004-02
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10. Erythrocytes may contain a ouabain-insensitive K+-ATPase which plays a role in internal K+ balance
Erythrocytes are useful in evaluating K+ transport pathways involved in internal K+ balance. Several forms of H+,K+-ATPase have been described in nephron segments active in K+ transport. Furthermore, the activity of a ouabain-insensitive isoform of H+,K+-ATPase expressed in collecting duct cells may be modulated by acid-base status. Various assays were perfo
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-12
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11. PeroxidaÃÃo lipÃdica em pacientes esquistossomÃticos esplenectomizados da zona da mata e em ratos submetidos à Dieta BÃsica Regional (DBR)
The aim of this study was to investigate the oxidative stress in plasma and erytrhocytes from schistossomiasis mansoni patients subjected to clinical and splenectomy treatment associated with auto-implantation of spleen tissue, as well as, in young rats fed with a Regional Basic Diet (RBD) which has been used in the sugarcane rural area of Pernambuco state.
Publicado em: 2003
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12. Solubilização de membranas de eritrocitos por surfactantes da serie Tween
Surfactants present hemolytic effects and depending on their concentration, they can either protect or solubilize erythrocyte membrane. In this work we have studied the interaction of nonionic surfactants from the Tween series (polyoxyethylenesorbitan) with human erythrocytes membranes. Triton Xl00 (t-octylphenoxypolyethoxyethanol) was used as a control, in
Publicado em: 2000