Eph Ephrin System
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Análise dos mecanismos de neuroplasticidade na porção lombar da medula espinal do rato submetida à lesão isquêmica fototrombótica e tratada pela injeção local de PEDF / Analysis of neuroplasticity mechanisms in lumbar levels of the rat spinal cord submitted to photothrombotic ischemia and treated with local injection of PEDF
O fator derivado do epitélio pigmentado (PEDF) é um fator neurotrófico que possui um grande potencial trófico nos neurônios motores da medula espinal, bem como é capaz de modular o microambiente da lesão. Desta forma, analisamos a capacidade do tratamento com PEDF em promover a neuroplasticidade da medula espinal após lesão isquêmica. Ratos Wistar
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/03/2012
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2. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon guidance and bundling in the developing brain, control cell migration and adhesion, and help patterning the embryo. Here we report that two ephrinB ligands and three EphB receptors are expressed in and regulate the formation of the vascular network. Mice lacking ep
Cold Spring Harbor Laboratory Press.
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3. EphrinB reverse signaling in cell-cell adhesion: Is it just par for the course?
Cell-cell adhesion is a critical process for the formation and maintenance of tissue patterns during development, as well as invasion and metastasis of cancer cells. Although great strides have been made regarding our understanding of the processes that play a role in cell-cell adhesion, the precise mechanisms by which diverse signaling events regulate cell
Landes Bioscience.
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4. Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome
Craniofrontonasal syndrome (CFNS) is an X-linked developmental disorder that shows paradoxically greater severity in heterozygous females than in hemizygous males. Females have frontonasal dysplasia and coronal craniosynostosis (fusion of the coronal sutures); in males, hypertelorism is the only typical manifestation. Here, we show that the classical female
National Academy of Sciences.