Energetic Metabolism
Mostrando 13-24 de 89 artigos, teses e dissertações.
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13. Classification of brain tumor extracts by high resolution ¹H MRS using partial least squares discriminant analysis
High resolution proton nuclear magnetic resonance spectroscopy (¹H MRS) can be used to detect biochemical changes in vitro caused by distinct pathologies. It can reveal distinct metabolic profiles of brain tumors although the accurate analysis and classification of different spectra remains a challenge. In this study, the pattern recognition method partial
Braz J Med Biol Res. Publicado em: 2011-02
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14. Metabolism and brain cancer
Cellular energy metabolism is one of the main processes affected during the transition from normal to cancer cells, and it is a crucial determinant of cell proliferation or cell death. As a support for rapid proliferation, cancer cells choose to use glycolysis even in the presence of oxygen (Warburg effect) to fuel macromolecules for the synthesis of nucleot
Clinics. Publicado em: 2011
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15. Isoenzymatic variability in wild potatoes.
Two species of wild potato Solanum commersonii, subspecies commersonii and malmeanum, and S. chacoense, subspecies muelleri occur in southern Brazil. Their rusticity and easy adaptation to extreme climatic conditions make them valuable for breeding programs. The objective of this work was to analyze the isoenzymatic variability of 113 clones of wild potato s
Pesquisa Agropecuaria Brasileira. Publicado em: 2011
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16. Avaliação de parâmetros hemogasométricos e bioquímicos durante infusão contínua de detomidina em equinos em estação
A detomidina é um agonistas ¿2 adrenérgicos amplamente empregado para sedação, analgesia e medicação pré-anestésica em equinos. A ativação dos receptores ¿2 distribuídos no Sistema Nervoso Central e Periférico provoca uma série de alterações fisiológicas, tais como bradicardia, bloqueio átrio-ventricular, diminuição do débito cardíaco,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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17. Beta-glucosidase activity of soybean epicotyls in germination.
Isoflavones are compounds with benefits for human health and they are the mainly forms of glycosides in vegetables. ?-glucosidase (?-D-glucoside glucohydrolase, E.C.3.2.1.21) hydrolyses ?-D-glucosides releasing glucose and forming aglycone isoflavones. The aglycone isoflavone is the most bioavailable form of the glycosides. ?-glucosidase that converts glycos
CONGRESSO INTERNACIONAL DE BIOPROCESSOS NA INDÚSTRIA DE ALIMENTOS. Publicado em: 2011
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18. Germ band retraction as a landmark in glucose metabolism during Aedes aegypti embryogenesis
Background: The mosquito A. aegypti is vector of dengue and other viruses. New methods of vector control are needed and can be achieved by a better understanding of the life cycle of this insect. Embryogenesis is a part of A. aegypty life cycle that is poorly understood. In insects in general and in mosquitoes in particular energetic metabolism is well studi
Publicado em: 2010
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19. CREATINE INCREASES Na+,K+-ATPase ACTIVITY AND PREVENTS SEIZURES INDUCED BY PENTYLENETETRAZOLE IN RATS / CREATINA AUMENTA A ATIVIDADE DA Na+,K+-ATPase E PREVINE O APARECIMENTO DAS CONVULSÕES INDUZIDAS POR PENTILENOTETRAZOL EM RATOS
Creatine, an endogenous guanidino compound produced on liver, kidneys, pancreas, testes and brain, has been aim of several studies over the last years. Although most studies attribute the effects of creatine to their energetic buffer role, recent findings have suggested actions non-related to energy metabolism. Researches have shown that this compound may ac
Publicado em: 2010
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20. Produção e caracterização de leptina e TcPTP1 recombinantes, proteínas ligadas ao metabolismo, sinalização celular e inflamação. / Production and characterization of recombinant leptin and TcPTP1, proteins linked to metabolism, cell sinalization and inflamation.
Leptin is predominantly secreted by adipocytes and plays an important role in the regulation of the energetic metabolism of mammals. Because of this, leptin is strongly involved in the regulation of obesity. After ligation, dimerization and activation of its specific receptor in the hypothalamus, leptin activates JAK kinases that phosphorylate STAT transcrip
Publicado em: 2010
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21. Alterações metabólicas e o papel da mitocôndria no processo de tumorigênese de astrocitomas humanos / Metabolic alterations and the role of mitochondria in tumorigenic process of human astrocytomas
Mitochondria has a key role in cell survival and death. Mitochondrial DNA (mtDNA) alterations, for example, amplification, homoplasmic mutation, deletion and depletion, and their clinical and pathological implications have been analyzed in human malignancies. In order to search for mitochondrial alterations associated to tumorigenesis, this study aimed to an
Publicado em: 2010
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22. Alterações metabólicas ao longo da ontogenia das larvas de cachara (Pseudoplatystoma reticulatum Siluriforme, Pimelodidae, Linnaeus, 1776) e do híbrido / Metabolic alteration during the ontogeny of the cachara larvae (Pseudoplatystoma reticulatum Siluriforme, Pimelodidae, Linnaeus, 1776) and the hybrid
O ciclo de vida de muitos organismos inclui um estágio larval de desenvolvimento que é morfologicamente distinto do adulto. Durante o período embrionário e larval os processos dominantes mais importantes são: crescimento, diferenciação de tecidos e/ou alterações fisiológicas, acompanhadas de mudanças nas exigências nutricionais, e mobilização d
Publicado em: 2010
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23. A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information
The current drug options for the treatment of chronic Chagas disease have not been sufficient and high hopes have been placed on the use of genomic data from the human parasite Trypanosoma cruzi to identify new drug targets and develop appropriate treatments for both acute and chronic Chagas disease. However, the lack of a complete assembly of the genomic se
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-12
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24. Estudos de alterações funcionais de macrofagos submetidos a hipoxia no modelo in vitro da leishmaniose / Studies of funcional alterations of macrophages submetted to hypoxia in ana in vitro model of leishmaniasis
Regions of low oxygen tension (hypoxia) are common features of inflamed/infected tissues. The analyses of cell phenotypic alterations by hypoxia are helpful for understanding of the pathological mechanisms and treatment resistance and for the development of cellular therapies. Macrophages, cells involved in the clearance of microorganisms from infected tissu
Publicado em: 2009