Endoplasmic Reticulum Stress
Mostrando 13-24 de 234 artigos, teses e dissertações.
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13. Efeitos de acidos graxos na indução de inflamação hipotalamica / Effects of fatty acids on the induction of hypothalamic inflammation
In animal models of diet-induced obesity, the activation of an inflammatory response in the hypothalamus produces molecular and functional resistance to the anorexigenic hormones insulin and leptin. The primary events triggered by dietary fats that ultimately lead to hypothalamic cytokine expression and inflammatory signaling are unknown. Here, we test the h
Publicado em: 2009
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14. Study of endoplasmatic reticulum stress-related proteins in the maternal pancreatic islets remodeling during the peripartum / Estudo da expressão das proteínas envolvidas no estresse de retículo endoplasmático durante o remodelamento das ilhotas pancreáticas maternas no período perinatal
During gestation occurs increase on the proliferation and apoptosis reduction of pancreatic b cells. Prolactin (PRL) promotes these changes which are reverted after delivery. Dexametasone (DEX) in vitro opposed to PRL. We evaluate whether endoplasmatic reticulum stress (ERS) was involved on post-delivery apoptosis and glycocorticoids (GC) participate on this
Publicado em: 2009
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15. Genetic transformation of sugarcane by biolistic and Agrobacterium tumefaciens to study the mechanism of programmed cell death / Transformação genética de cana-de-açúcar por biolística e Agrobacterium tumefaciens visando estudar o mecanismo de morte celular programada
Sugarcane is one of the main crops planted in Brazil and presents significant socioeconomic and agribusiness importance to the country. The world scene is quite favorable as regards the marketing of its two main products, sugar and alcohol, driving the development of the national sugar-alcohol sector. Therefore, the sugarcane genetic breeding appears as the
Publicado em: 2009
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16. Inibição do proteasoma aumenta o estresse oxidativo e bloqueia a resposta da NADPH oxidase a estímulos em células musculares lisas vasculares / Proteasome Inhibiton increases oxidative stress and disrupts NADPH oxidase response to stimuli in vascular smooth muscle cells
Cellular processes governing vascular Nox family NADPH oxidases in disease conditions are unclear. Since redox processes are intrinsic to cell stress response, we asked whether oxidative stress merges with other types of stress via Nox(es). We focused on proteasome inhibition as a relevant stress condition. Vascular smooth muscle cells (VSMC) incubation with
Publicado em: 2009
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17. Estudos funcionais e estruturais da proteina humana hnRNP Q/NSAP1 / Funcional and structural studies of human protein hnRNPQ
The members of the hnRNPs family (heterogenous nuclear ribonuclein proteins) play important roles in gene expression control and mRNAs metabolism. The proteins hnRNPD (AUF1) and hnRNPQ (NSAP1) were the main targets of this study. AUF1 has two RNA recognition motifs (RRM) and participates in the process of destabilization of a class of mRNAs that contain AU-r
Publicado em: 2008
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18. Avaliação da hiperhomocisteinemia leve na evolução da aterosclerose em camundongos normais, com hemofilia B, deficiencia dos receptores para LDL ou da apolipoproteina E / Evaluation of mild hyperhomocysteinemia in the development of atherosclerosis in normal, hemophiliac B, LDL receptor-deficient or apolipoprotein E-deficient mice
This study evaluated the effect of controlled mild hyperhomocysteinemia (HHcy) in the development of atherosclerosis using normal, apolipoprotein E-deficient (apoE-/-), LDL receptor-deficient (LDLR-/-), or hemophilia B mice. We quantified atherosclerotic lesions at the aortic sinus and analyzed endoplasmic reticulum (RE) stress by western-blot technique. Con
Publicado em: 2008
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19. Chlorhexidine toxicity injected in the paw of mice and added to cultured L929 fibroblasts / Toxicidade da clorexidina injetada na pata de camundongos e adicionada em cultura de fibroblastos L929
Como a clorexidina (CHX) tem sido recomendada como solução irrigadora de canais radiculares e como curativo de demora, o objetivo do presente estudo foi caracterizar in vivo a lesão induzida pela injeção de CHX a 0,125, 0,25, 0,5 e 1,0% na pata de camundongos em intervalos de tempo selecionados (24 e 48 horas e 7 e 14 dias) e in vitro o modo e a causa m
Publicado em: 2007
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20. Perfilização transcricional revela sobreposição entre as respostas induzidas por estresses osmótico e do retículo endoplasmático em soja / Transcriptional profiling reveals overlap between ER- and osmotic-stress responses in soybean
Despite the potential of the endoplasmic reticulum (ER) stress response to accommodate adaptive pathways, its integration with other environmental-induced responses is poorly understood in plants. Here, we performed global expression profiling on soybean leaves exposed to polyethylene glycol treatment or to unfolded protein response (UPR) inducers to identif
Publicado em: 2006
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21. Formation of concentric whorls of rough endoplasmic reticulum in the adrenal gland of the Mongolian gerbil.
All cortical cells appeared alike in fetal gerbils of both sexes though glomerulosa cells were distinguishable at the time of birth. Fenestrated cisternae of rough endoplasmic reticulum were observed in all cortical cells of fetal gerbils, but smooth endoplasmic reticulum predominated. Concentric whorls of rough endoplasmic reticulum first appeared in adreno
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22. 壽The mammalian endoplasmic reticulum as a sensor for cellular stress
The recent elucidation of the mammalian unfolded protein response pathway has revealed a unique and transcriptionally complex signal transduction pathway that protects cells from a variety of physical and biochemical stresses that can occur during normal development and in disease states. Although the stress conditions are monitored in the endoplasmic reticu
Cell Stress Society International.
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23. Translational control in the endoplasmic reticulum stress response
American Society for Clinical Investigation.
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24. Endoplasmic Reticulum Stress Regulates Adipocyte Resistin Expression
American Diabetes Association.