Endocytosis
Mostrando 13-24 de 1236 artigos, teses e dissertações.
-
13. Trypanosoma cruzi: Contribuição ao estudo da endocitose dependente e independente de clatrina em formas epimastigotas. / Trypanosoma cruzi: Contribution to the study of the dependent and independent endocytosis of clatrina in epimastigote forms.
Endocitose em células eucarióticas é o processo de incorporação de macromoléculas por diferentes vias, com diversas proteínas associadas. Este processo ocorre através do brotamento de vesículas na membrana plasmática e endereçamento destas vesículas a compartimentos endossomais no citoplasma. Os tripanossomatídeos são protozoários flagelados p
Publicado em: 2007
-
14. Expression of USP2a and study of its interaction with clathrin in human oral squamous carcinoma and prostate cancer cells / Estudo da expressão da enzima desubiquitinante USP2a e de sua interação com a proteina clatrina em celulas derivadas de carcinomas espinocelulares bucais e de prostata humanos
The ubiquitin (Ub)-proteasome pathway controls cellular protein turnover by degrading targeted intracellular proteins tagged with poly-Ub chains. Ubiquitination is a reversible process and the deubiquitinating enzymes (DUBs) are proteases that specifically cleave off Ub from Ub-protein conjugates. They can act in a preproteasomal level removing the poly-Ub t
Publicado em: 2007
-
15. Sinais de tráfego envolvidos no envolvidos no endereçamento do transportador vesicular de acetilcolina (VAChT)
The vesicular acetylcholine transporter (VAChT) is the protein responsible for packaging cytoplasmic acetylcholine (ACh) into the synaptic vesicle of cholinergic neurons. The cytosolic C-terminal region of VAChT is important in intracellular trafficking events and targeting to secretory organelles. In this study, we evaluate the existence of trafficking sign
Publicado em: 2006
-
16. Internalização e tráfego da Stress Inducible Protein-1 (STI-1), um ligante da proteína prion celular
The cellular prion protein (PrPc) is a glycosylphosphatidylinositol (GPI)-anchored plasma membrane glycoprotein. The PrPc abnormal isoform, PrPsc, is an infectious form involved in the prion disease pathogenesis. Identification of ligands that interact with PrPc can help in the understanding the physiological function of this protein. The STI-1 (stress induc
Publicado em: 2006
-
17. Expression of the receiver for mannose in cells of Schwann and Schwannoma ST88-14. / Expressão do receptor para manose em células de Schwann e Schwannoma ST88-14.
The mannose receptor (MR) is a transmembrane glycoprotein that is expressed in several cell types but little or no information is available on Schwann cells (SC). We show that rodent SC in primary cultures of dissociated cells or explant nerve cultures and a human Schwannoma cell line (ST88-14) bind the exogenous MR ligand neoglycoprotein mannosyl/bovine ser
Publicado em: 2006
-
18. ESTUDO MORFOFUNCIONAL DAS CÉLULAS DE SERTOLI DE RATOS ALBINOS TRATADOS COM ETOPOSIDE NA FASE PRÉ-PÚBERE. / Morphological and functional evalution of Sertoli cells from albino treated with etoposide during preopubertal phase. / ESTUDO MORFOFUNCIONAL DAS CÉLULAS DE SERTOLI DE RATOS ALBINOS TRATADOS COM ETOPOSIDE NA FASE PRÉ-PÚBERE. / Morphological and functional evalution of Sertoli cells from albino treated with etoposide during preopubertal phase.
Spermatogenesis is a complex and controlled process in which Sertoli cells play a key role. In the testis, endocrine, paracrine and autocrine mechanisms that control spermatogenesis occurrence. The Sertoli cells synthesize substances which are essential for these mechanisms. Among them is transferrin. This protein is an important iron transporter that binds
Publicado em: 2006
-
19. Caracterização de microdomínios de membrana resitentes a detergente não iônico em promastigotas de Leishmania (Viannia) braziliensis. Papel dos microdomínios na infectividade. / Characterization of non-ionic detergent resistant membrane microdomains in Leishmania (Viannia) braziliensis promastigotes. Role of these microdmains in the infectivity
Glycoconjugates present in Leishmania surface are an important class of molecules involved in parasite-macrophage interaction. The structural elucidation of Leishmania (Viannia) braziliensis promastigote glycolipids is very relevant because in this specie the glycolipids represent the major promastigote surface glycoconjugate. Six glycolipid fractions, terme
Publicado em: 2006
-
20. Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NCI-H82 variant small cell lung cancer
The aim of the present study was to characterize the interactions of antagonist G (H-Arg-D-Trp-NmePhe-D-Trp-Leu-Met-NH 2)-targeted sterically stabilized liposomes with the human variant small cell lung cancer (SCLC) H82 cell line and to evaluate the antiproliferative activity of encapsulated doxorubicin against this cell line. Variant SCLC tumors are known t
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-08
-
21. Morfologia e histoquimica do epidismo do gerbilio, Meriones unguiculatus
Epididymidis epithelium of the gerbil (Meriones unguiculatus) was focused in four distinct regions e.g., initial segment, caput, corpus and cauda of the epididymis in which were characterized five cell types: principal, apical, basal, halo and clear cells. These cells were not will characterised on1y in the thin and straight epididymal corpus that showed col
Publicado em: 2004
-
22. Nephrotoxicity of Bence-Jones proteins: interference in renal epithelial cell acidification
The aim of the present study was to evaluate the acidification of the endosome-lysosome system of renal epithelial cells after endocytosis of two human immunoglobulin lambda light chains (Bence-Jones proteins, BJP) obtained from patients with multiple myeloma. Renal epithelial cell handling of two BJP (neutral and acidic BJP) was evaluated by rhodamine fluor
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-03
-
23. Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells
A construct (AT1R-NF) containing a "Flag" sequence added to the N-terminus of the rat AT1 receptor was stably expressed in Chinese hamster ovary cells and quantified in the cell membrane by confocal microscopy after reaction with a fluorescein-labeled anti-Flag monoclonal antibody. Angiotensin II bound to AT1R-NF and induced endocytosis with a half-time of 2
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-09
-
24. Nephrotoxicity of Bence-Jones proteins: correlation with endocytosis by BHK cells and intracellular movement
O objetivo deste trabalho foi avaliar a endocitose de duas proteínas de Bence Jones por células renais, com a finalidade de elucidar a interferência de características físico-químicas na nefrotoxicidade. As proteínas de Bence Jones (denominadas AK e GL) forma purificadas e isoladas da urina de dois pacientes com mieloma múltiplo. Isótopos de ambas a
Brazilian Archives of Biology and Technology. Publicado em: 2001-06