Encapsulation
Mostrando 37-48 de 428 artigos, teses e dissertações.
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37. Development and Validation of a Stability-Indicating Method for Perillyl Alcohol Incorporated in Poly(lactide-co-glycolide) Nanoparticles and Stress Degradation Studies
Perillyl alcohol has been studied in the treatment of cancer disease. However, its high toxicity is a drawback, which can be overcome by its incorporation in nanostructured systems. The aim of this work was to develop and validate a chromatographic method for determination of perillyl alcohol encapsulation efficiency in a polymeric nanoparticles formulation
J. Braz. Chem. Soc.. Publicado em: 2017-12
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38. Nanostructured magnetic alginate composites for biomedical applications
Abstract This is a study of the preparation and characterization of polymeric-magnetic nanoparticles. The nanoparticles used were magnetite (Fe3O4) and the chosen polymers were alginate and chitosan. Two types of samples were prepared: uncoated magnetic nanoparticles and magnetic nanoparticles encapsulated in polymeric matrix. The samples were analyzed by XR
Polímeros. Publicado em: 2017-12
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39. Coencapsulation of trans-Dehydrocrotonin and trans-Dehydrocrotonin:hydroxypropyl-β-cyclodextrin into Microparticles
The aim of this study was to develop and characterize poly-ε-caprolactone (PCL) and poly(D,L-lactic-co-glycolic)-acid (PLGA) microparticles containing coencapsulated trans-dehydrocrotonin (t-DCTN) and t-DCTN:hydroxypropyl-β-cyclodextrin inclusion complex (t-DCTN:HP-β-CD), with t-DCTN loaded at concentrations ranging from 11.25 to 45.00 mg. A preformulatio
J. Braz. Chem. Soc.. Publicado em: 2017-08
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40. Fatty acids profile of chia oil-loaded lipid microparticles
ABSTRACT Encapsulation of poly-unsaturated fatty acid (PUFA)is an alternative to increase its stability during processing and storage. Chia (Salvia hispanica L.) oil is a reliable source of both omega-3 and omega-6 and its encapsulation must be better evaluated as an effort to increase the number of foodstuffs containing PUFAs to consumers. In this work chia
Braz. J. Chem. Eng.. Publicado em: 2017-07
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41. Thermo-Mechanical Properties of P(HB-HV) Nanocomposites Reinforced by Nanodiamonds
Several studies of biodegradable polymers and copolymers have been carried for different applications in the biomedical area. This current study aims to develop a biocomposite to be used as an orthopedic device, using poly(3-hydroxybutyrate-co-3-hydroxyvalerate) P(HB-HV), a biodegradable copolymer, with 94%HB and 6%HV, as matrix; and nanodiamonds (ND) with p
Mat. Res.. Publicado em: 26/06/2017
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42. A simple HPLC method for the determination of halcinonide in lipid nanoparticles: development, validation, encapsulation efficiency, and in vitro drug permeation
ABSTRACT Halcinonide is a high-potency topical glucocorticoid used for skin inflammation treatments that presents toxic systemic effects. A simple and quick analytical method to quantify the amount of halcinonide encapsulated into lipid nanoparticles, such as polymeric lipid-core nanoparticles and solid lipid nanoparticles, was developed and validated regard
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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43. In Vitro Mid-Term Conservation of Acorus calamus L. via Cold Storage of Encapsulated Microrhizome
ABSTRACT In vitro rhizome production, encapsulation and cold storage of Acorus calamus were attempted for its propagation and ‘true-to-type’ conservation. Shoot cultures were initiated using underground rhizome buds, on 6-benzyladenine (BA) containing Murashige and Skoog (MS) medium. Maximum microrhizome production was observed in presence of 33.3 µM BA
Braz. arch. biol. technol.. Publicado em: 22/06/2017
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44. Liposomes as potential carriers for ketorolac ophthalmic delivery: formulation and stability issues
ABSTRACT Drug delivery to treat ocular disorders locally is a challenging endeavor. Traditional ocular dosage form - eye drops - exhibits poor availability, consequently inefficient therapeutic response. The objective of the study was to formulate and characterize a ketorolac tromethamine ocular system with a prolonged release pattern based on liposomes as a
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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45. A stability-indicating HPLC-PDA method for the determination of ferulic acid in chitosan-coated poly(lactide-co-glycolide) nanoparticles
ABSTRACT The development and validation of a simple and efficient method for the quantification of ferulic acid in poly (D,L-lactide-co-glycolide) (PLGA) nanoparticles coated with chitosan (CS) by reverse phase high performance liquid chromatography coupled to photodiode array detection was described. For the chromatographic analysis, a reverse phase C-18 co
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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46. Development and Characterization of Synthetic Chalcones-Loaded Eudragit RS 100 Microparticles for Oral Delivery
Eudragit® RS100 microspheres of two chalcones were prepared by solvent evaporation technique. A simple and rapid high-performance liquid chromatography (HPLC) method was developed and validated to determine the encapsulation efficiency, drug loading and release profiles of these chalcones in a microparticulate system. The mean EE values for the two chalcone
J. Braz. Chem. Soc.. Publicado em: 2017-06
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47. Hepatic toxicity caused by PLGA-microspheres containing usnic acid from the lichen C ladonia substellata (AHTI) during pregnancy in Wistar rats
ABSTRACT This study aimed to evaluate the teratogenic and hepatotoxic potential of the usnic acid encapsulated into PLGA-microspheres. In total, 12 female Wistar rats in pregnancy were randomly distributed in the control group (n= 6) that received 1.0 mL of physiological solution and treatment group (n= 6) that received 25 mg/kg of encapsulated usnic acid by
An. Acad. Bras. Ciênc.. Publicado em: 2017-06
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48. Production and characterization of nanocapsules encapsulated linalool by ionic gelation method using chitosan as wall material
Abstract Linalool has been extensively applied in various fields, such as flavoring agent, perfumes, cosmetics and medical science. However, linalool is unstable, volatile and readily oxidizable. A sensitive substance can be encapsulated in a capsule, so encapsulation technology can solve these problems. In this paper, linalool-loaded nanocapsules (Lin-nanoc
Food Sci. Technol. Publicado em: 25/05/2017