Dynamic Clamp
Mostrando 1-12 de 38 artigos, teses e dissertações.
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1. Dissecação dinâmica de condutâncias iônicas em tempo real / Dynamic dissection of ionic conductances in real time
Investigamos o papel de condutâncias iônicas lentas na transmissão/codificação de informação entre neurônios que disparam em rajadas ou bursts. Para isso, desenvolvemos um protocolo experimental no qual a interação em tempo real entre computador e neurônio biológico permite isolar o efeito da dinâmica de um determinado tipo de canal iônico e es
Publicado em: 2011
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2. Experimental and theoretical study of a telemetric dynamic torque meter
This paper presents the development of a dynamic torque meter to be applied to rotating shafts using electronic transduction, strain gage, telemetry and LabView Graphic programming. A mathematical model was developed. The electronic transduction signal is transmitted by digital modulation from a remote transduction unit fixed to a shaft to a base station, se
Journal of the Brazilian Society of Mechanical Sciences and Engineering. Publicado em: 2010-09
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3. Modelagem estocástica de neurônios e sua interação em tempo real com neurônios biológicos / Stochastic neural modelling and interfacing neurons and models in real-time
We developed a mathematical model of the electrical activity of a motor neuron from the stomatogastric ganglion of crustaceans. It was inspired on a previous existing deterministic model which is considered as electrophysiologically plausible in the recent literature. However, this deterministic model were not able to reproduce the irregular bursting behavio
Publicado em: 2008
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4. Estudo do Segmento Consenso Adjacente ao Domínio TM2 e parte do Domínio TM2 do Receptor P2X7: Dinâmica Molecular e Atividade de Canal Iônico. / Study of the segment adjacent consensus to domain TM2 and part of domain TM2 of receiver P2X7: molecular dynamics and activity of ionic canal.
The purinergic receptor P2X7 (P2X7R) is a membrane protein which forms channels in the presence of extracellular ATP. Once opened, the channels allow the transport of cations through the cellular membrane, being expressed preferentially in immune cells. Among all purinergic receptors, P2X7R has distinct characteristics from other P2X (P2XR) members. For exam
Publicado em: 2007
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5. Implementação de um protocolo Dynamic Clamp em sistema Linux em tempo real para a produção de condutâncias em neurônios biológicos e eletrônicos / Implementation of a protocol dynamic clamp in system Linux in real time for the production of artifical conductances in biological and electronic neurons
O protocolo conhecido como Dynamic Clamp consiste em utilizar um computador para introduzir condutâncias artificiais em um neurônio biológico. O modo como estas condutâncias dependem da voltagem da membrana ou do tempo são modelado por equações diferenciais que são integradas em tempo real por um computador conectado ao neurônio biológico. Resumida
Publicado em: 2006
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6. Comportamento complexo em centros geradores de padrões / Complex behavior in central pattern generators
Realizamos simulações computacionais de modelos da atividade elétrica de centros geradores de padrões para investigar o fato experimental de organismos vivos utilizarem neurônios caóticos para produzir padrões periódicos. Centros geradores de padrões biológicos produzem atividades motoras periódicas que devem ser robustas a pequenas flutuações d
Publicado em: 2005
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7. Stress-Strain Curves of Nafion Membranes in Acid and Salt Forms
Nafion membranes have been studied using dynamic mechanical analysis in the controlled force mode and clamp of tension film measurements for as received commercial Nafion membranes with different solvent contents and with different cations (Li+, Na+, K+, Rb+ and Cs+). In comparison with as-received Nafion membranes, the initial slope of the stress-strain cur
Polímeros. Publicado em: 2002
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8. Cinematica e Dinamica de uma maquina injetora de plasticos
The simulation of an injection molding machine clamp mechanism is presented in this work aiming data generation to design in a wiser way. A computational program was written, for mechanism kinematic and dynamic analysis, considering the constraints, the mechanism geometry, friction between components, geometric properties (mass, inertia and gravity center) a
Publicado em: 1999
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9. Glucose effectiveness assessed under dynamic and steady state conditions. Comparability of uptake versus production components.
Glucose tolerance is determined by both insulin action and insulin-independent effects, or "glucose effectiveness," which includes glucose-mediated stimulation of glucose uptake (Rd) and suppression of hepatic glucose output (HGO). Despite its importance to tolerance, controversy surrounds accurate assessment of glucose effectiveness. Furthermore, the relati
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10. A peptide switch regulates DNA polymerase processivity
Chromosomal DNA polymerases are tethered to DNA by a circular sliding clamp for high processivity. However, lagging strand synthesis requires the polymerase to rapidly dissociate on finishing each Okazaki fragment. The Escherichia coli replicase contains a subunit (τ) that promotes separation of polymerase from its clamp on finishing DNA segments. This repo
National Academy of Sciences.
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11. Context-Dependent Effects of NMDA Receptors on Precise Timing Information at the Endbulb of Held in the Cochlear Nucleus
Many synapses contain both AMPA receptors (AMPAR) and N-methyl-d-aspartate receptors (NMDAR), but their different roles in synaptic computation are not clear. We address this issue at the auditory nerve fiber synapse (called the endbulb of Held), which is formed on bushy cells of the cochlear nucleus. The endbulb refines and relays precise temporal informati
American Physiological Society.
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12. Anthropomorphizing the Mouse Cardiac Action Potential via a Novel Dynamic Clamp Method
Interspecies differences can limit the translational value of excitable cells isolated from model organisms. It can be difficult to extrapolate from a drug- or mutation-induced phenotype in mice to human pathophysiology because mouse and human cardiac electrodynamics differ greatly. We present a hybrid computational-experimental technique, the cell-type tran
The Biophysical Society.