Duffy Blood Group System
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Duffy blood group system and the malaria adaptation process in humans
Malaria is an acute infectious disease caused by the protozoa of the genus Plasmodium. The antigens of the Duffy Blood Group System, in addition to incompatibilities in transfusions and hemolytic disease of the newborn, are of great interest in medicine due to their association with the invasion of red blood cells by the parasite Plasmodium vivax. For invasi
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011-02
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2. Duffy gene polymorphism study in patients with malignant hypertension and blood donors / Estudo dos polimorfismos do gene DUFFY em pacientes com hipertensão maligna e doadores de sangue
Essential hypertension has a high prevalence worldwide and the has genetic and environment causes. Searching genetics correlation for hypertension, a potential role of DARC (Duffy Antigen Receptor of Chemokines) was described as an Interleukine-8 receptor in endothelium and that this interaction might contribute for the pathogenesis of pre-eclampsia. DARC is
Publicado em: 2008
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3. Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite.
cDNA clones encoding the major subunit of the Duffy blood group were isolated from a human bone marrow cDNA library using a PCR-amplified DNA fragment encoding an internal peptide sequence of glycoprotein D (gpD) protein. The open reading frame of the 1267-bp cDNA clone indicated that gpD protein was composed of 338 amino acids, predicting a M(r) of 35,733,
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4. Deletion of the Murine Duffy Gene (Dfy) Reveals that the Duffy Receptor Is Functionally Redundant
All of the antigenic determinants of the Duffy blood group system are in a glycoprotein (gp-Fy), which is encoded by a single-copy gene (FY) located on chromosome 1. gp-Fy is also produced in several cell types, including endothelial cells of capillary and postcapillary venules, the epithelial cell of kidney collecting ducts, lung alveoli, and the Purkinje c
American Society for Microbiology.