Drug Combination
Mostrando 13-24 de 1027 artigos, teses e dissertações.
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13. Usefulness of 3’- 5’ IS6110-RFLP genotyping and spoligotyping of Mycobacterium tuberculosis isolated in a tertiary hospital: a retrospective study detecting unsuspected epidemiological events
ABSTRACT A drug resistance survey involving Mycobacterium tuberculosis isolated from patients of a tertiary Hospital in the Rio de Janeiro city (RJ), Brazil, between the years 1996 and 1998 revealed a high frequency of isoniazid (HR) resistance. These isolates were revisited and genotyped. Patients came from different RJ neighborhoods and municipalities, and
Rev. Inst. Med. trop. S. Paulo. Publicado em: 12/09/2019
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14. Benzbromarone in the treatment of gout
Abstract Background Benzbromarone is a uricosuric drug that has been used in the treatment of gout over the last 30 years. Due to its potent inhibition of the dominant apical (luminal) urate exchanger in the human proximal tubule URAT1, it reduces the urate reabsorption, diminishing serum urate levels and therefore preventing gout flares. Main body of the
Adv. rheumatol.. Publicado em: 15/08/2019
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15. Efeitos dos probióticos no perfil lipídico: revisão sistemática
Resumo As alterações na microbiota intestinal podem modular mecanismos envolvendo fatores de risco para doenças cardiovasculares, incluindo as dislipidemias. O objetivo foi revisar os efeitos da suplementação de probióticos na prevenção e no tratamento de alterações do perfil lipídico. As pesquisas foram feitas na base de dados PubMed, com os desc
J. vasc. bras.. Publicado em: 15/08/2019
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16. DRUG CONSUMPTION, KNOWLEDGE ON THE CONSEQUENCES OF CONSUMPTION AND ACADEMIC PERFORMANCE AMONG COLLEGE STUDENTS IN SAN SALVADOR, EL SALVADOR
RESUMO Objetivo: determinar a relação entre o uso de drogas, o conhecimento das consequências do consumo e o desempenho acadêmico, para o álcool, cocaína e maconha, entre estudantes de graduação em ciências sociais e em saúde de San Salvador, El Salvador. Método: foi utilizado questionário de modelo transversal, com amostra de conveniência de
Texto contexto - enferm.. Publicado em: 08/08/2019
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17. 2017 recommendations of the Brazilian Society of Rheumatology for the pharmacological treatment of rheumatoid arthritis
Abstract The objective of this document is to provide a comprehensive update of the recommendations of Brazilian Society of Rheumatology on drug treatment of rheumatoid arthritis (RA), based on a systematic literature review and on the opinion of a panel of rheumatologists. Four general principles and eleven recommendations were approved. General principles:
Adv. rheumatol.. Publicado em: 29/07/2019
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18. Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis
Abstract Objectives: To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS®) in capsules in patients with osteoarthritis (OA) of the knee. Methods: Multicenter, randomized, double-b
Adv. rheumatol.. Publicado em: 29/07/2019
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19. Early use of polymyxin B reduces the mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection
ABSTRACT Polymyxin B is one of the last resort option for carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection in China. Therefore, the timing of administration of polymyxin is frequently delayed. We collected 40 cases of CRKP bloodstream infections (BSIs) treated with combinations based on polymyxin B over 30 months. The primary outcome,
Braz J Infect Dis. Publicado em: 20/05/2019
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20. Development and evaluation of multiparticulate biphasic system for the treatment of circadian diseases
Multiparticulate systems have biopharmaceutical advantages when compared to the monolithic systems, once they allow different patterns of drug release and can be used in different treatments. The aim of the present work was to develop a biphasic controlled release delivery system, using propranolol hydrochloride (PROP) that can be used for the treatment of c
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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21. Development and Validation of UHPLC-MS/MS for Simultaneous Determination of Scutellarin and Salicylic Acid in Rat Plasma: Application to Herb-Drug Pharmacokinetic Interaction Study
Dengzhanxixin injection (DI) product has been clinically proven to be effective for treating cardio-cerebrovascular disease. Furthermore, herb-drug interactions between the DI product and drugs that are commonly co-administered, such as aspirin, must be explored to ensure safe clinical use. A reliable ultra-performance liquid chromatography-tandem mass spect
J. Braz. Chem. Soc.. Publicado em: 2019-04
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22. Effect of co-administration of BRL-37344 and tadalafil on reduction of overactive bladder symptoms after induction of detrusor overactivity in mice
Abstract Purpose: To evaluate the impact of the combination of BRL 37344 and tadalafil (TDF) on the reduction of overactive bladder (OB) symptoms. Methods: Thirty mice were randomized into 5 groups (G) of 6 animals each. L-NAME was used to induce DO. G1: Control; G2: L-NAME; G3: L-NAME + TDF; G4: L-NAME + BRL 37344; G5: L-NAME + TDF + BRL 37344. After 30
Acta Cir. Bras.. Publicado em: 28/02/2019
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23. Quando a experiência é capturada pela representação: governamentalização das drogas na Saúde e no sistema de justiça criminal
A conjunção entre o saber médico e as práticas jurídicas é um importante vetor de governamentalização de verdades que instrumentalizam a intervenção sobre a chamada questão da droga sob a perspectiva de uma gestão populacional. No encontro das experiências em torno de duas pesquisas nesse campo, o presente relato articula as vivências dos pesqu
Interface (Botucatu). Publicado em: 14/02/2019
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24. Use of sodium-glucose cotransporter-2 inhibitors and urinary tract infections in type 2 diabetes patients: a systematic review
RESUMO Os inibidores do cotransportador de sódio-glicose do tipo 2 (SGLT2i) são medicamentos que atuam mantendo a glicosúria. Estudos recentes têm demonstrado efeitos promissores desses no tratamento de diabetes mellitus tipo 2 (DM2). No entanto, pode haver um risco aumentado de desenvolver infecções do trato urinário (UTI) em pacientes tratados com e
Rev. Assoc. Med. Bras.. Publicado em: 2019-02