Drosophila Wing Spot Test
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. DNA damage protective effect of honey-sweetened cashew apple nectar in Drosophila melanogaster
Abstract Fruits and derivatives, such as juices, are complex mixtures of chemicals, some of which may have mutagenic and/or carcinogenic potential, while others may have antimutagenic and/or anticancer activities. The modulating effects of honey-sweetened cashew apple nectar (HSCAN), on somatic mutation and recombination induced by ethyl methanesulfonate (EM
Genet. Mol. Biol.. Publicado em: 25/07/2016
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2. Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster
This study investigated the genotoxicity of Lapachol (LAP) evaluated by wing spot test of Drosophila melanogaster in the descendants from standard (ST) and high bioactivation (HB) crosses. This assay detects the loss of heterozygosity of marker genes expressed phenotypically on the fly's wings. Drosophila has extensive genetic homology to mammals, which make
Genetics and Molecular Biology. Publicado em: 23/07/2010
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3. Avaliação da atividade genotóxica do lapachol e β-lapachona e anticarcinogênica do lapachol, em células somáticas de Drosophila melanogaster
This study investigated the genotoxicity of Lapachol (LAP) evaluated by wing spot test of Drosophila melanogaster in the descendants from standard (ST) and high bioactivation (HB) crosses. This assay detects the loss of heterozygosity of marker genes expressed phenotypically on the flys wings. Drosophila has extensive genetic homology to mammals, which makes
Publicado em: 2010
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4. AVALIAÇÃO MUTAGÊNICA E ANTIMUTAGÊNICA DO EXTRATO AQUOSO DE MIMOSA HOSTILIS BENTH PELO TESTE DE MUTAÇÃO E RECOMBINAÇÃO SOMÁTICA EM ASAS DE DROSOPHILA MELANOGASTER (SMART). / MUTAGENIC AND ANTIMUTAGENIC EVALUATION OF MIMOSA HOSTILIS BENTH AQUEOUS EXTRACT BY THE WING SPOT TEST IN DROSOPHILA MELANOGASTER (SMART).
A planta Jurema preta (Mimosa hostilis) é tradicionalmente utilizada em regiões semi-áridas do Brasil, com fins analgésicos e antiinflamatórios, na forma de chá das cascas. Apesar do uso popular de plantas com fins medicinais, estudos detalhados sobre a ação dos constituintes nos organismos necessitam de maiores investigações, pois se conhece que a
Publicado em: 2010
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5. Effect of organic tomato ( Lycopersicon esculentum ) extract on the genotoxicity of doxorubicin in the Drosophila wing spot test
The consumption of organic tomatoes (ORTs) reduces the risk of harmful effects to humans and the environment caused by exposure to toxic agrochemicals. In this study, we used the somatic mutation and recombination test (SMART) of wing spots in Drosophila melanogaster to evaluate the genotoxicity of ORT and the effect of cotreatment with ORT on the genotox
Genetics and Molecular Biology. Publicado em: 17/01/2009
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6. Efeito protetor do chá verde (Camellia sinensis) contra a ação genotóxica da doxorrubicina, em células somáticas de Drosophila melanogaster
The green tea is considered a functional food with antioxidant activity, and this delays the process of old age and helps in the prevention of chronicle and degenerative diseases, such as cancer and heart affections. Of catechins, present in green tea, may is extremely important in the inactivation of free radicals, which provoke damages to the DNA molecules
Publicado em: 2008
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7. Efeitos protetores do Panax Ginseng C. A. Meyer sobre a genotoxicidade da doxorrubicina em células somáticas de Drosophila melanogaster
O Panax ginseng é um dos fitoterápicos mais amplamente prescritos para o tratamento de câncer, diabetes, inflamação crônica, doenças cardiovasculares e neurodegenerativas. Desde que o uso de medicamentos alternativos, em combinação com a terapia convencional, pode aumentar o risco de interações indesejáveis, investigamos a possível genotoxicidad
Publicado em: 2008
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8. Avaliação das águas superficiais do Rio Paraguai no trecho de Cáceres (MT) pelo teste de micronúcleos em peixes e teste mancha de asas de Drosophila
CAPITULO II: A atividade genotóxica de amostras de águas superficiais, de quatro sítios ao longo do Rio Paraguai em Cáceres, Estado de Mato Grosso, Brasil, foi avaliada utilizando a o Teste para Detecção de Mutação e Recombinação Somática (SMART) em asas de Drosophila melanogaster. Efluentes dos esgotos sanitários e agro-industriais (efluentes re
Publicado em: 2008
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9. Impacto genotÃxico de poluentes quÃmicos presentes na Ãgua e sedimento do Rio Japaratuba (Sergipe)
In situ investigations of the effects of mutagenic pollutants (environmental monitoring) have increasingly used bioindicators, and fish often have been used in these studies as sentinel organisms. In the present study, we have used the piscine micronucleus test (MNT) as an in situ biological indicator of chemical contamination in two fresh water fish species
Publicado em: 2006
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10. Avaliação genotóxica de líquido de vesícula e extrato salino da forma metacestódea de Taenia solium e de agentes antiparasitários benzimidazólicos
Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system (CNS) caused by cysticerci of the helminth Taenia solium, which is prevalent in developing countries and re-emerging in affluent societies. This helminth has been associated with brain tumours and haematological malignancies in humans. The possible mechanisms leading
Publicado em: 2004