Double Emulsion
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Effects of bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) release from polylactide-poly (ethylene glycol)-polylactide (PELA) microcapsule-based scaffolds on bone
Multiple growth factors can be administered to mimic the natural process of bone healing in bone tissue engineering. We investigated the effects of sequential release of bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) from polylactide-poly (ethylene glycol)-polylactide (PELA) microcapsule-based scaffolds on bone regeneratio
Braz J Med Biol Res. Publicado em: 30/11/2017
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2. Coencapsulation of trans-Dehydrocrotonin and trans-Dehydrocrotonin:hydroxypropyl-β-cyclodextrin into Microparticles
The aim of this study was to develop and characterize poly-ε-caprolactone (PCL) and poly(D,L-lactic-co-glycolic)-acid (PLGA) microparticles containing coencapsulated trans-dehydrocrotonin (t-DCTN) and t-DCTN:hydroxypropyl-β-cyclodextrin inclusion complex (t-DCTN:HP-β-CD), with t-DCTN loaded at concentrations ranging from 11.25 to 45.00 mg. A preformulatio
J. Braz. Chem. Soc.. Publicado em: 2017-08
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3. Macromolecular confinement of therapeutic protein in polymeric particles for controlled release: insulin as a case study
ABSTRACT Sustained release systems for therapeutic proteins have been widely studied targeting to improve the action of these drugs. Molecular entrapping of proteins is particularly challenging due to their conformational instability. We have developed a micro-structured poly-epsilon-caprolactone (PCL) particle system loaded with human insulin using a simple
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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4. In vitro and in vivo evaluation of nano-based films for buccal delivery of zolpidem
Abstract Insomnia is becoming increasingly prevalent in the world general population. Therapies used by patients include over-the-counter therapies, herbal and dietary supplements, and pharmacological or nonpharmacological treatments. Among these, zolpidem is a pharmacological treatment popularly used for insomnia. Zolpidem is well tolerated and especially e
Braz. oral res.. Publicado em: 28/11/2016
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5. Superparamagnetic maghemite loaded poly (ε- caprolactone) nanocapsules : characterization and synthesis optimization
Iron oxide nanoparticles (ION) have been studied for essential applications, like detection of biological constituents (virus, bacterials, cell, nucleic acids, protein, enzyme, etc.), magnetic bioseparation and clinic therapy and diagnosis (such as MRI magnetic fluid and hyperthermia). In this work, γ-Fe2O3has been synthetized by a adapted sol-gel method a
Matéria (Rio J.). Publicado em: 2014-03
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6. Síntese e caracterização de copolímeros do tipo ABA para encapsulação de hemoglobina bovina
The use of biopolymers for the development of oxygen carriers has been extensively investigated. In this work, three different ABA triblock copolymers were synthesized and used to encapsulate purified bovine hemoglobin, using a double emulsion technique. The effect of polymer composition, homogenization velocity, and addition of a surfactant, on the protein
Química Nova. Publicado em: 2012
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7. Desenvolvimento e caracterização de nanocompósitos produzidos a partir de miniemulsão acrílica aquosa contendo nanopartículas de prata
Lately, the polymer latices have gained increasing importance having the great advantage of using water as a solvent, that reduces the emission of volatile organic compounds a big environmental concern. In the industry, the polymeric latices are obtained usually through an emulsion polymerization. They can also be obtained by the polymerization in miniemulsi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/05/2011
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8. Caracterização de nanopartículas contendo insulina em modelos de animais induzidos ao diabetes / Characterization of nanoparticles containing insulin in animal models induced diabetes
Diabetes Mellitus is a disease whose cases have increased due to the bad habits of life of society. Several strategies have been developed for the treatment of diabetes, especially the controlled release of drugs. The erroneous use of insulin as basal treatment of diabetes takes a problem, since the high dose of the drug can lead to severe hypoglycemia. The
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/08/2010
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9. Physicochemical characterization of a hydrophilic model drug-loaded PHBV microparticles obtained by the double emulsion/solvent evaporation technique
Micropartículas de poli(3-hidroxibutirato-co-3-hidroxivalerato) (PHBV) contendo um fármaco modelo hidrofílico, o cloridrato de metformina (MH), foram obtidas pela técnica de emulsão múltipla/evaporação do solvente. Diversas formulações foram preparadas, com o objetivo de investigar a influência de cada composição sobre a eficiência de encapsula
Publicado em: 2010
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10. Preparação e caracterização de nanoparticulas com heparina e sua avaliação em modelo animal de trombose venosa / Preparation and characterization of heparin-loaded nanoparticles and its evaluation in animal model of venous thrombosis
Heparin is an anticoagulant widely used in the treatment and prophylaxis of deep vein thrombosis (DVT). Some limitations of its use is the cost and route of administration, intravenous or subcutaneous, sometimes in repeated doses in 24 hours. Thus, the development of a product that can be administered subcutaneously in a smaller number of applications or ora
Publicado em: 2010
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11. Physicochemical characterization of a hydrophilic model drug-loaded PHBV microparticles obtained by the double emulsion/solvent evaporation technique
Micropartículas de poli(3-hidroxibutirato-co-3-hidroxivalerato) (PHBV) contendo um fármaco modelo hidrofílico, o cloridrato de metformina (MH), foram obtidas pela técnica de emulsão múltipla/evaporação do solvente. Diversas formulações foram preparadas, com o objetivo de investigar a influência de cada composição sobre a eficiência de encapsula
J. Braz. Chem. Soc.. Publicado em: 2008
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12. Estabilização de latex polimericos por sorção de solventes organicos
The colloidal stability with regard to NaCI addition of homopolymer (PS-M and PS-LEV) polystyrene latexes and copolymer (P(SBMA), PS/PBMA and PBMA/PS) poly[styrene-co- butylmethacrylate)] latexes was modified by particle swelling with toluene and chloroform vapor, at 25°C. The latexes were obtained by aqueous emulsion polymerization. K2S2O4 and Na2S204 were
Publicado em: 1998