Dosage Analysis
Mostrando 1-12 de 500 artigos, teses e dissertações.
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1. Dose-ranging effects of SGLT2 inhibitors in patients with type 2 diabetes: a systematic review and meta-analysis
ABSTRACT The lowest dosage of empagliflozin (10 mg) showed similar benefits on glycated hemoglobin (HbA1c) level, body weight, blood pressure, and total and cardiovascular mortality in comparison with the highest available dose (25 mg) in the EMPAREG trial. These findings have not been clearly demonstrated for canagliflozin and dapagliflozin. The objective w
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Investigation of maternal polymorphisms in genes related to glucose homeostasis and the influence on birth weight: a cohort study
Abstract Objectives: To contribute to a better understanding of the maternal genetic mechanisms that influence obstetric outcomes and that are involved in maternal and child health, this study aimed to evaluate the association between maternal genetic variants and the offspring birth weight by analyzing single-nucleotide polymorphisms (SNPs) in genes relate
Jornal de Pediatria. Publicado em: 2022
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3. Cardiac Shock Wave Therapy for Coronary Heart Disease: an Updated Meta-analysis
Abstract Introduction: The aim of this article is to study the efficacy and safety of cardiac shock wave therapy (CSWT) in the treatment of coronary heart disease (CAD). Methods: A comprehensive search of electronic databases and a manual search of conference papers and abstracts were performed until September 30, 2018. The studies using RevMan 5.3 and STA
Braz. J. Cardiovasc. Surg.. Publicado em: 2020-10
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4. A retrospective cohort study to screen linezolid-induced thrombocytopenia in adult patients hospitalized in the Midwestern Region of Brazil
ABSTRACT Background: Thrombocytopenia (TP) is the major event associated with linezolid (LZD) therapy. We investigated the incidence and risk factors for thrombocytopenia in hospitalized adults who received LZD (1200 mg/day) between 2015 and 2017. HIV-positive, death during follow-up and those with a baseline platelet count ≤100 × 103/mm3 were excluded.
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
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5. Post-elastic Deformation Characteristics of Hybrid Fibre Reinforced Concrete Composites
Abstract The present study was focused on evaluating the strength and failure properties of hybrid micro-fibre concretes containing micro brass and steel fibre additions. Experimental tests were conducted on different hybrid fibre concretes containing aligned fibres in the direction of beam axis and the relative mechanical performance was compared to randoml
Lat. Am. j. solids struct.. Publicado em: 10/01/2020
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6. NEW APPLICATIONS FOR AMOXICILLIN DETERMINATION IN PURE FORM AND PHARMACEUTICALS BASED ON IODATE-IODIDE MIXTURE: TITRIMETRY AND SPECTROSCOPY STUDIES
Three simple methods are described for the determination of amoxicillin (AMX) in bulk drug and dosage forms using iodate-iodide mixture reagent. These methods employed the well-known analytical reaction between iodate-iodide mixture in the presence of acid solution. The iodide oxidized by iodate to iodine in an amount equivalent to the -COOH group present in
Quím. Nova. Publicado em: 2020-01
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7. Preformulation of a liquid dosage formulation of captopril for pediatric use: drug-excipient compatibility and stability studies
Currently, medications used in children are typically modified from pharmaceutical dosage forms designed for adults. Captopril is widely adapted to liquid formulations for use in hospitals. Its stability in the aqueous medium is reduced since it undergoes oxidation producing captopril disulfide (its main metabolite). The aim of this formulation study was to
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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8. Expression Analysis of Pyrenophora teres f. maculata-Responsive Loci in Hordeum vulgare
Abstract Pyrenophora teres f. maculata is the causal agent of barley spot form net blotch (SFNB), a major stubble-borne disease in many barley-growing areas worldwide. In plants, the Nucleotide-Binding Site-Leucine-Rich Repeat (NBS-LRR) gene family functions in immunity against a variety of pathogens and pests. From a pre-established set of NBS-type resistan
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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9. Trapa natans pericarp extract ameliorates hyperglycemia and hyperlipidemia in type 2 diabetic mice
Abstract The pericarp of Trapa natans L., an annual aquatic floating herb belonging to Lythraceae family, is used as a folk medicine in China. In this study, extracts of Trapa natans pericarp were tested both in vitro and in vivo through a high-fat diet with a single medium dosage streptozotocin injection induced type 2 diabetic mice. Different solvent extra
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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10. Polímero hidrorretentor e fertilização mineral na implantação de híbrido de Eucalyptus urophylla x Eucalyptus grandis
Resumo O uso de polímeros hidrorretentores surge como uma alternativa para disponibilizar água de forma adequada na fase de implantação de povoamentos florestais, além de reter nutrientes necessários para o estabelecimento e desenvolvimento destes. No presente trabalho, objetivou-se avaliar o efeito do polímero hidrorretentor e a influência de difere
Ciênc. Florest.. Publicado em: 02/12/2019
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11. Effect of metronidazole on placental and fetal development in albino rats
Abstract Metronidazole is an antiprotozoal and antibacterial used in gynecology and obstetrics for the treatment of parasitic infections. However, despite having clinical use for more than three decades, questions about the safety of its use during pregnancy is not well understood. Thus, the present study evaluated the effect of metronidazole on placental an
Anim. Reprod.. Publicado em: 25/11/2019
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12. Human Chorionic Gonadotropin monotherapy for the treatment of hypogonadal symptoms in men with total testosterone > 300 ng/dL
ABSTRACT Purpose The 2018 American Urological Association guidelines on the Evaluation and Management of Testosterone Deficiency recommended that 300 ng/dL be used as the threshold for prescribing testosterone replacement therapy (TRT). However, it is not uncommon for men to present with signs and symptoms of testosterone deficiency, despite having testost
Int. braz j urol.. Publicado em: 07/11/2019