Dorsal Hippocampus
Mostrando 13-24 de 89 artigos, teses e dissertações.
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13. Involvement of the hippocampus, amygdala, entorhinal cortex in memory consolidation
A total of 182 young adult male Wistar rats were bilaterally implanted with cannulae into the CA1 region of the dorsal hippocampus and into the amygdaloid nucleus, the entorhinal cortex, and the posterior parietal cortex. After recovery, the animals were trained in a stepdown inhibitory avoidance task. At various times after training (0, 30, 60 or 90 min) th
Publicado em: 2010
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14. Differential role of entorhinal and hippocampal nerve growth factor in short- and long-term memory modulation
We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention. In order to evaluate the modulation of entorhinal and hippocampal NGF in shortand long-term memory, animals were implanted with cannulae in the CA1 area of the dorsa
Publicado em: 2010
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15. Achados histopatológicos e comportamentais em modelo experimental de esquizofrenia induzida por - MAM - acetato de metilazoximetanol
Esquizofrenia (SZ) é uma doença multifacetada que afeta vários domínios, incluindo sintomas positivos e negativos. Devido a isso, até o momento, não existe um modelo animal adequado de SZ, o que contribui para o fato de sua fisiopatologia ainda ser pouco conhecida. Um dos melhores modelos animais de SZ desenvolvidos usa acetato metilazoximetanol (MAM),
Publicado em: 2010
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16. Núcleo mediano da rafe e estresse de nado forçado: papel dos receptores de glutamato de tipo NMDA / Median Raphe Nucleus and Forced Swim stress: role of glutamate NMDA receptors
Exposure to uncontrollable stressors leads to behavioral and neurochemical changes, which has been associated to mal functioning of the Median Raphe Nucleus (MnRN)-Dorsal Hippocampus (DH) serotoninergic pathway. These deficits can be attenuated by intra-hippocampal injections of NMDA antagonists or 5-HT1a agonists. Activation of MnRN glutamatergic NMDA recep
Publicado em: 2010
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17. Análise dos eventos tônicos e fásicos do sono dessincronizado em ratos Wistar com lesão medular contusa / Análise dos eventos tônicos e fásicos do sono dessincronizado em ratos Wistar com lesão medular contusa
After a spinal cord injury (SCI), structural reorganization occurs locally and at multiple levels of the central nervous system (CNS). Compromising of sensory motor functions and significant alterations of other neural functions are normally related after a SCI. The circardians rhythms, specially the sleep-wake cycle are frequently affected after a trauma or
Publicado em: 2009
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18. Protein tyrosine kinase inhibitors modify kainic acid-induced epileptiform activity and mossy fiber sprouting but do not protect against limbic cell death
Intrahippocampal administration of kainic acid (KA) induces synaptic release of neurotrophins, mainly brain-derived neurotrophic factor, which contributes to the acute neuronal excitation produced by the toxin. Two protein tyrosine kinase inhibitors, herbimycin A and K252a, were administered intracerebroventricularly, in a single dose, to attenuate neurotrop
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-05
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19. Distribution of neuronal nitric oxide synthase immunoreactive cells for neural in the hippocampus of pigeon after food-choice learning / Distribuição de celulas imunorreativas para sintase neuronal do oxido nitrico (nNOS) no hipocampo de pombos (Columba livia) apos aprendizagem de escolha alimentar
The hippocampus has fundamental role in spatial learning and memory processes. Functional and neurochemical analysis of the hippocampus are favored by evidence on spatial learning in mammals and birds. The present study examined the immunohistochemical expression of nNOS-positive cells in the hippocampus of pigeons (C. livia) after training in food location
Publicado em: 2007
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20. Aspectos do envelhecimento cerebral e função cognitiva em modelo experimental animal e estudo de mecanismos de neurodegeneração em cultura celular
The two phenomena, biological and behavioural, approached in the present work are brain aging and spatial memory. Several studies, comparative and experimental, have shown that aged subjects present significantly impaired performances in different types of cognitive tasks. It is also known that contradictions in literature exist in relation to consequences o
Publicado em: 2007
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21. Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test
It has been demonstrated that exposure to a variety of stressful experiences enhances fearful reactions when behavior is tested in current animal models of anxiety. Until now, no study has examined the neurochemical changes during the test and retest sessions of rats submitted to the elevated plus maze (EPM). The present study uses a new approach (HPLC) by l
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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22. Differential role of entorhinal and hippocampal nerve growth factor in short- and long-term memory modulation
We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention. In order to evaluate the modulation of entorhinal and hippocampal NGF in short- and long-term memory, animals were implanted with cannulae in the CA1 area of the dor
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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23. POLIAMINAS MODULAM A MEMÓRIA NAS TAREFAS DE MEDO CONDICIONADO E ESQUIVA INIBITÓRIA EM RATOS / POLYAMINES MODULATE MEMORY IN FEAR-CONDIDIONING AND INHIBITORY AVOIDANCE TASKS IN RATS.
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of N-methyl-D-aspartate (NMDA) receptors. The processes mediated by NMDA receptor include synaptic plasticity and formation of neural circuitry.
Publicado em: 2004
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24. A brain microdialysis study on 5-HT release in freely moving rat lines selectively bred for differential 5-HT1A receptor function
Breeding for high and low hypothermic responses to systemic administration of a serotonin1A (5-HT1A) receptor agonist (8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT) has resulted in high DPAT-sensitive (HDS) and low DPAT-sensitive (LDS) lines of rats, respectively. These lines also differ in several behavioral measures associated with stress. In the pres
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02