Dnl
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Uma métrica complementar para definir uma zona tampão em aeroporotos brasileiros
A legislação sobre o ruído de aeronaves no Brasil reconhece a métrica DNL como a única ferramenta para implementar zoneamento de ruído em aeroportos. Este artigo analisa a importância da adoção de uma métrica auxiliar para caracterizar os impactos do ruído das aeronaves em construções específicas sensíveis ao ruído, especialmente na análise
J. Transp. Lit.. Publicado em: 2014-10
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2. Desempenho de pré-escolares em desenvolvimento normal de linguagem em tarefa de flexão de tempo verbal no passado
A aquisição da flexão de tempo verbal é um processo gradual, realizado inicialmente sem conhecimento de significado e regra que diferencia as formas. Objetivo: Verificar a habilidade gramatical de flexão de tempo verbal no passado em crianças em desenvolvimento normal de linguagem (DNL). Métodos: Foram sujeitos 30 crianças em DNL, com idades en
CoDAS. Publicado em: 2014-02
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3. Fuzzy Modeling of Annoyance Caused by Aircraft Noise Using Laeqd and Laeqn Metrics
ABSTRACT: Airport noise presents a major environmental impact arising from aircrafts airport activities, being one of the most complex and difficult mitigation problems. From the environmental point of view, airports cause serious problems to the population. Annoyance caused by noise was evaluated from the Day-Night Level (DNL) metrics proposed by Schultz. H
J. Aerosp. Technol. Manag.. Publicado em: 2013-03
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4. Representação fonológica em crianças com Distúrbio Específico de Linguagem (DEL)
TEMA: crianças com Distúrbio Especifico de Linguagem (DEL) apresentam dificuldades no processamento de fala e esses prejuízos afetam o desenvolvimento de representações fonológicas. OBJETIVOS: avaliar as habilidades de crianças em Desenvolvimento Normal de Linguagem (DNL) e com DEL em distinguir palavras de pseudopalavras em uma tarefa de decisão lex
Pró-Fono Revista de Atualização Científica. Publicado em: 2010-09
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5. Representação semântica e nomeação em crianças com distúrbio específico de linguagem
TEMA: crianças com distúrbio específico de linguagem (DEL) apresentam déficits lexicais como os primeiros sinais observáveis nesta desordem, caracterizado por dificuldades de acesso lexical em provas de nomeação e discurso. Estudos comparando a nomeação de figuras com desenhos parecem ideais para esclarecer os déficits lexicais. OBJETIVO: comparar
Pró-Fono Revista de Atualização Científica. Publicado em: 2010-06
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6. Biochemical and genetic characterization of the DNA ligase encoded by Saccharomyces cerevisiae open reading frame YOR005c, a homolog of mammalian DNA ligase IV.
Here we demonstrate that the Saccharomyces cerevisiae DNA ligase activity, which we previously designated DNA ligase II, is encoded by the genomic DNA sequence YOR005c. Based on its homology with mammalian LIG4, this yeast gene has been named DNL4 and the enzyme activity renamed Dnl4. In agreement with others, we find that DNL4 is not required for vegetative
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7. Acute fever and delayed leukoencephalopathy following low dose intraventricular methotrexate.
Nine out of 14 patients treated with intraventricular methotrexate (MTX) for meningeal carcinomatosis from breast carcinoma and surviving more than 4 months developed disseminated necrotising leukoencephalopathy (DNL). All four patients who had received both intraventricular MTX and whole brain radiotherapy developed DNL. Five of the six patients who experie
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8. Short-term alterations in carbohydrate energy intake in humans. Striking effects on hepatic glucose production, de novo lipogenesis, lipolysis, and whole-body fuel selection.
Short-term alterations in dietary carbohydrate (CHO) energy are known to alter whole-body fuel selection in humans, but the metabolic mechanisms remain unknown. We used stable isotope-mass spectrometric methods with indirect calorimetry in normal subjects to quantify the metabolic response to six dietary phases (5 d each), ranging from 50% surplus CHO (+50%
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9. Reduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in mice
The nuclear liver X receptor (LXR) regulates multiple aspects of cholesterol, triacylglycerol (TG), and carbohydrate metabolism. Activation of LXR induces the expression of genes encoding enzymes involved in de novo lipogenesis (DNL) resulting in hepatic steatosis in mice. Pharmacological LXR activation has also been reported to improve insulin sensitivity a
American Society for Biochemistry and Molecular Biology.
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10. NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the Ligase IV pathway
In the yeast Saccharomyces cerevisiae, DNA double strand break (DSB) repair by nonhomologous end-joining (NHEJ) requires the DNA end-binding heterodimer Yku70p–Yku80p and the ligase Dnl4p associated with its cofactor Lif1p. NHEJ efficiency is down-regulated in MATa/MATα cells relative to MATa or MATα cells, but the mechanism of this mating type regulatio
Cold Spring Harbor Laboratory Press.
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11. CD20-targeted tetrameric interferon-α, a novel and potent immunocytokine for the therapy of B-cell lymphomas
Interferon-α (IFN-α) has direct inhibitory effects on some tumors and is a potent stimulator of both the innate and adaptive immune systems. A tumor-targeting antibody-IFN-α conjugate (mAb-IFN-α) could kill by direct actions of the monoclonal antibody (mAb) and IFN-α on tumor cells and also potentiate a tumor-directed immune response. The modular Dock-a
American Society of Hematology.
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12. A New XRCC1-Containing Complex and Its Role in Cellular Survival of Methyl Methanesulfonate Treatment
DNA single-strand break repair (SSBR) is important for maintaining genome stability and homeostasis. The current SSBR model derived from an in vitro-reconstituted reaction suggests that the SSBR complex mediated by X-ray repair cross-complementing protein 1 (XRCC1) is assembled sequentially at the site of damage. In this study, we provide biochemical data to
American Society for Microbiology.