Dna Damage
Mostrando 25-36 de 3112 artigos, teses e dissertações.
-
25. Genotoxicity of titanium dioxide nanoparticles and triggering of defense mechanisms in Allium cepa
Abstract Titanium dioxide nanoparticles (TiO2NPs) are widely used and may impact the environment. Thus, this study used a high concentration of TiO2NP (1000 mg/L) to verify the defense mechanisms triggered by a plant system – an indicator of toxicity. Furthermore, this study aimed at completely characterizing TiO2NP suspensions to elucidate their toxic beh
Genet. Mol. Biol.. Publicado em: 27/06/2019
-
26. Phenotype-oriented NGS panels for mucopolysaccharidoses: Validation and potential use in the diagnostic flowchart
Abstract Mucopolysaccharidosis (MPS) are a group of rare genetic disorders caused by deficiency in the activity of specific lysosomal enzymes required for the degradation of glycosaminoglycans (GAGs). A defect in the activity of these enzymes will result in the abnormal accumulation of GAGs inside the lysosomes of most cells, inducing progressive cellular da
Genet. Mol. Biol.. Publicado em: 11/04/2019
-
27. RESISTANCE EXERCISE PROTOCOL DOES NOT CAUSE ACUTE GENOTOXIC EFFECTS IN TRAINED INDIVIDUALS
RESUMO Introdução: O treinamento resistido, principalmente a musculação, vem progressivamente ganhando novos adeptos em todo o mundo. Apesar de haver um significativo aumento no número de pesquisas e na literatura disponível sobre o assunto, o treinamento resistido vem passando por um importante processo de evolução. O metabolismo anaeróbico, que c
Rev Bras Med Esporte. Publicado em: 2019-04
-
28. In vitro Antiproliferative and inhibition of oxidative DNA damage activities of n-butanol extract of Limonium bonduelli from Algeria
Abstract Plants are the main sources of natural antioxidants in the form of phenolic compounds, which help human beings to deal with oxidative stress, caused by free radical damage. For this reason, the present study was carried out to evaluate the antiproliferative, antioxidant and inhibition of oxidative DNA damage activities of n-butanol extract obtained
Braz. arch. biol. technol.. Publicado em: 28/03/2019
-
29. Avaliação química, ecotoxicológica e genotoxicológica de águas de cavas de mineração a céu aberto
RESUMO Lagos artificiais formados em áreas de mineração a céu aberto são unidades complexas e se constituem em passivos ambientais emergentes advindos da indústria da mineração. Embora estejam aumentando em número em várias partes do globo, são um problema ambiental recente e ainda pouco estudado, especialmente no tocante à qualidade e à toxicid
Eng. Sanit. Ambient.. Publicado em: 21/03/2019
-
30. DNA damage and primordial follicle activation after in vitro culture of sheep ovarian cortex in Morus nigra leaf extract
RESUMO: Este estudo avaliou o efeito do extrato das folhas de Morus nigra, com ou sem suplementos, sobre a morfologia, a ativação e o dano ao DNA de folículos pré-antrais cultivados inclusos em tecido ovariano. Os ovários foram coletados e divididos em fragmentos, sendo um fixado para análise histológica e ensaio de marcação de terminações dUTP me
Pesq. Vet. Bras.. Publicado em: 2019-01
-
31. Oxidative stress: therapeutic approaches for cervical cancer treatment
OBJECTIVES: Oxidative stress results from an imbalance between the generation and elimination of oxidant species. This condition may result in DNA, RNA and protein damage, leading to the accumulation of genetic alterations that can favor malignant transformation. Persistent infection with high-risk human papillomavirus types is associated with inflammatory
Clinics. Publicado em: 10/12/2018
-
32. Assessment of toxicity and oxidative DNA damage of sodium hypochlorite, chitosan and propolis on fibroblast cells
Abstract The objective of this study was to evaluate and compare the cytotoxicity and genotoxicity on human fibroblast cell lines of sodium hypochlorite (NaOCl), chitosan and propolis as root canal irrigating solutions. Human fibroblast cells were exposed to chitosan, propolis and NaOCl for 4 and 24 h. Cell viability was assessed by 2,3-bis-(2-methoxy-4-nitr
Braz. oral res.. Publicado em: 29/11/2018
-
33. The pequi pulp oil (Caryocar brasiliense Camb.) provides protection against aging-related anemia, inflammation and oxidative stress in Swiss mice, especially in females
Abstract Continued exposure to reactive oxygen species and inflammation are the rationale behind aging theories and associated diseases. Scientific evidence corroborates the ethnomedicinal use of the oil of pequi (Caryocar brasiliense Camb.), a typical Brazilian Cerrado fruit, against oxidative damage to biomolecules and inflammation. We aimed to investigate
Genet. Mol. Biol.. Publicado em: 29/11/2018
-
34. Brown Flaxseed Prevents DNA Damage Induced by 1,2-Dimethylhydrazine in a Pre-Clinical Model
ABSTRACT The study evaluated the effects of brown flaxseed supplementation in natura on the prevention of DNA damage induced by 1,2-dimethylhydrazine (DMH) in vivo. The experimental groups were Negative and Positive Controls and the protocols of Pre-treatment, Simultaneous, Post-treatment, Pre+continuous in relation to the supplementation of brown flaxseed a
Braz. arch. biol. technol.. Publicado em: 14/11/2018
-
35. Evaluation of Dietary Supplement Intake (Yeast Tablets) on Pregnant Albino Rats and Their Fetuses (Implications of Yeast Tablets on Rats & Fetuses)
ABSTRACT Histopathological studies in placenta, liver, kidney, apoptotic DNA damage and p53 mutation estimation of pregnant rats and their offspring exposed to dietary supplement yeast tablets, were carried out. Pregnant female albino rats were orally administrated yeast tablets at concentration 41.1 mg/kg during gestation period. Hematoxylin and eosin stain
Braz. arch. biol. technol.. Publicado em: 14/11/2018
-
36. Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function
The tumor suppressive role of oridonin, an active compound extracted from Rabdosia rubescens, has been proven in several gastric cancer (GC) cell lines. The present study aimed to evaluate the effect of oridonin on another GC cell line, SNU-216, and explore the potential mechanisms. The viable cell numbers, cell migration, survival fraction, and cell viabili
Braz J Med Biol Res. Publicado em: 14/11/2018