Distinguishing Forms
Mostrando 13-24 de 63 artigos, teses e dissertações.
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13. The effect of selection on a long wavelength-sensitive (LWS) opsin gene of Lake Victoria cichlid fishes
In East African Lake Victoria >200 endemic species of haplochromine fishes have been described on the basis of morphological and behavioral differences. Yet molecular analysis has failed to reveal any species-specific differences among these fishes in either mitochondrial or nuclear genes. Although the genes could be shown to vary, the variations represent t
National Academy of Sciences.
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14. Cerebral biopsy in the investigation of presenile dementia due to cerebral atrophy.
Investigation by cerebral biopsy of patients with dementia associated with cerebral atrophy permits the examination of clinico-pathochemical relationships, and provides a means of distinguishing and classifying forms of cerebral atrophy. Benefits of the procedure must however be weighed against possible adverse effects of surgical intervention. The study exa
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15. Serological and histological diagnosis of primary biliary cirrhosis
A simple immunofluorescence test for antibody to a mitochondrial antigen present in many tissues is a reliable method of distinguishing most cases of primary biliary cirrhosis from jaundice due to extrahepatic biliary tract obstruction. Of 30 cases diagnosed as primary biliary cirrhosis, 26 had antimitochondrial antibody whereas none of 77 cases with jaundic
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16. New molecular forms of human liver alcohol dehydrogenase: isolation and characterization of ADHIndianapolis.
The biochemical determinants of alcoholism and genetic correlates for the variability in man's response to alcohol have remained obscure until recently. The identification of genetically determined isoenzymes of alcohol dehydrogenase with different catalytic properties may bear importantly upon this problem. New molecular forms of human liver alcohol dehydro
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17. Independent photocycles of the spectrally distinct forms of bacteriorhodopsin
Time-resolved, flash-induced difference absorbance spectra (300-700 nm) at pH 10.5 and 5°C for the bacteriorhodopsin photocycle fast and slow decaying forms of the M intermediate (Mf and Ms, respectively) and R intermediate are reported. The main distinguishing features are as follows: For Mf, ΔAmax = 412 nm, a shoulder at 436 nm, no absorbance change at 3
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18. Unique regulatory properties of the type 2a Ca2+ channel β subunit caused by palmitoylation
β subunits of voltage-gated Ca2+ channels are encoded in four genes and display additional molecular diversity because of alternative splicing. At the functional level, all forms are very similar except for β2a, which differs in that it does not support prepulse facilitation of α1C Ca2+ channels, inhibits voltage-induced inactivation of neuronal α1E Ca2+
The National Academy of Sciences.
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19. Corporate and philanthropic models of hospital governance: a taxonomic evaluation.
OBJECTIVE. We assess the theoretical integrity and practical utility of the corporate-philanthropic governance typology frequently invoked in debates about the appropriate form of governance for nonprofit hospitals operating in increasingly competitive health care environments. DATA SOURCES. Data were obtained from a 1985 national mailed survey of nonprofit
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20. Interorganizational factors affecting the delivery of primary care to older Americans.
OBJECTIVE: To discuss different types and forms of interorganizational linkages involved in the provision of primary care to older Americans, along with their distinguishing characteristics. RESEARCH STRATEGY: To take advantage of these linkage characteristics. The strategy requires a partnership with health services organizations and providers actually invo
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21. ASAP: the Alternative Splicing Annotation Project
Recently, genomics analyses have demonstrated that alternative splicing is widespread in mammalian genomes (30–60% of genes reported to have multiple isoforms), and may be one of their most important mechanisms of functional regulation. However, by comparison with other genomics data such as genome annotation, SNPs, or gene expression, there exists relativ
Oxford University Press.
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22. Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion
The structural protein VP6 of rotavirus, an important pathogen responsible for severe gastroenteritis in children, forms the middle layer in the triple-layered viral capsid. Here we present the crystal structure of VP6 determined to 2 Å resolution and describe its interactions with other capsid proteins by fitting the atomic model into electron cryomicros
Oxford University Press.
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23. Pea formaldehyde-active class III alcohol dehydrogenase: common derivation of the plant and animal forms but not of the corresponding ethanol-active forms (classes I and P).
A plant class III alcohol dehydrogenase (or glutathione-dependent formaldehyde dehydrogenase) has been characterized. The enzyme is a typical class III member with enzymatic parameters and substrate specificity closely related to those of already established animal forms. Km values with the pea enzyme are 6.5 microM for NAD+, 2 microM for S-hydroxymethylglut
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24. Different strains of rats develop different clinical forms of adjuvant disease.
Evidence is presented that a single injection of bacterial antigen in oil into a footpad of rats of 5 strains induced different clinical forms of adjuvant disease in the individual rat strains. Rats were injected with 300 micrograms heat-killed Mycobacterium tuberculosis in 50 microliters paraffin. Inflammatory lesions and clinical features were recorded on