Differential Proteomic Analysis
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Identification of the alpha-enolase P46 in the extracellular membrane vesicles of Bacteroides fragilis
BACKGROUND Members of the Bacteroides fragilis group are the most important components of the normal human gut microbiome, but are also major opportunistic pathogens that are responsible for significant mortality, especially in the case of bacteraemia and other severe infections, such as intra-abdominal abscesses. Up to now, several virulence factors have b
Mem. Inst. Oswaldo Cruz. Publicado em: 2018-03
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2. Proteomic analysis of halotolerant proteins under high and low salt stress in Dunaliella salina using two-dimensional differential in-gel electrophoresis
Abstract Dunaliella salina, a single-celled marine alga with extreme salt tolerance, is an important model organism for studying fundamental extremophile survival mechanisms and their potential practical applications. In this study, two-dimensional differential in-gel electrophoresis (2D-DIGE) was used to investigate the expression of halotolerant proteins u
Genet. Mol. Biol.. Publicado em: 13/05/2016
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3. Análise proteômica diferencial da fração periplasmática das estirpes A, B e C de Xanthomonas spp. que diferem na patogenicidade e espectro de citros hospedeiros
O presente trabalho teve por objetivo a análise proteômica comparativa da fração periplasmática das estirpes-genoma A, B e C de Xanthomonas spp, as quais diferem em patogenicidade e gama de citros hospedeiros. A estirpe A (Xanthomonas citri subsp. citri, Xac) é a mais virulenta e infecta todos os tipos de citros, enquanto que a estirpe B (Xanthomonas f
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/08/2012
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4. Efeito do fluoreto no osso de camundongos com diferentes susceptibilidades genéticas à fluorose: uma análise proteômica / Effect of fluoride on bone of mice with different genetic susceptibilities to fluorosis: a proteomic analysis
Genetic factors have been shown to influence bone and enamel responses to fluoride (F), but the molecular mechanisms involved remain unclear. In this study, a label-free proteomics approach was employed to identify and evaluate changes in bone protein expression of two mouse strains with different susceptibilities to fluorosis (A/J a susceptible strain, 129P
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/06/2012
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5. STGC3 inhibits xenograft tumor growth of nasopharyngeal carcinoma cells by altering the expression of proteins associated with apoptosis
STGC3 is a potential tumor suppressor that inhibits the growth of the nasopharyngeal carcinoma cell line CNE2; the expression of this protein is reduced in nasopharyngeal carcinoma compared with normal nasopharyngeal tissue. In this study, we investigated the tumor-suppressing activity of STGC3 in nude mice injected subcutaneously with Tet/pTRE-STGC3/CNE2 ce
Genetics and Molecular Biology. Publicado em: 02/02/2012
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6. Análise diferencial do proteoma da polpa de manga (Mangifera indica L.) e identificação de proteínas com variação de abundância durante o amadurecimento pós-colheita / Differential proteomic analysis of mango fruit pulp (Mangifera indica L.) during postharvest ripening
A manga (Mangifera indica L.) é cultivada em áreas tropicais e subtropicais, principalmente em países em desenvolvimento. Os maiores produtores são a Índia, China, México, Indonésia, Tailândia, Paquistão e Brasil, mas, por ser uma fruta altamente perecível, suas exportações têm sido limitadas. Durante o amadurecimento, as frutas adquirem caracte
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/05/2011
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7. Análise proteômica diferencial na carcinogênese gástrica. / Differential proteomic analysis in gastric carcinogenesis
O câncer gástrico é o quarto tipo de tumor mais comum e a segunda maior causa de morte por câncer no mundo. No Estado do Pará, essa neoplasia é um grave problema de saúde pública, pois é diagnosticada em estágios avançados, com taxas de sobrevida extremamente baixas. Esses fatos reforçam a gravidade dessa patologia e a necessidade de novos estudo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/04/2011
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8. Comparative proteomic analysis of pathogenic and non-pathogenic strains from the swine pathogen Mycoplasma hyopneumoniae
Background: Mycoplasma hyopneumoniae is a highly infectious swine pathogen and is the causative agent of enzootic pneumonia (EP). Following the previous report of a proteomic survey of the pathogenic 7448 strain of swine pathogen, Mycoplasma hyopneumoniae, we performed comparative protein profiling of three M. hyopneumoniae strains, namely the non-pathogenic
Publicado em: 2010
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9. Identificação de genes associados a produção de ocratoxina A em Aspergillus westerdijkiae
Mycotoxins, secondary metabolites of fungi, are toxic compounds found in great variety of foods, and when ingested can be very hazardous to animal and human health. Among the diverse mycotoxins, special interest has been given to the ochratoxin A (OA), produced by some species of Aspergillus and Penicillium. This mycotoxin is frequently found mainly in food
Publicado em: 2009
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10. Differential proteomic analysis of Bradyrizobium elkanii (SEMIA 587) / Análise proteômica diferencial do Bradyrizobium elkanii (SEMIA 587)
Este trabalho teve como objetivo principal realizar um estudo proteômico diferencial aplicado à amostra Bradyrizobium elkanii (SEMIA 587). Isso se fez através da identificação de proteínas diferencialmente expressas nesta importante bactéria fixadora de nitrogênio quando cultivada em laboratório (in vitro) e quando inoculada em plantas de soja (in v
Publicado em: 2008
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11. Proteomic analysis of the shistosome tegument and its surface membranes
The tegument surface of the adult schistosome, bounded by a normal plasma membrane overlain by a secreted membranocalyx, holds the key to understanding how schistosomes evade host immune responses. Recent advances in mass spectrometry (MS), and the sequencing of the Schistosoma mansoni transcriptome/genome, have facilitated schistosome proteomics. We detache
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-10
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12. Development of a Malignancy-Associated Proteomic Signature for Diffuse Large B-Cell Lymphoma
The extreme pathological diversity of non-Hodgkin’s lymphomas has made their accurate histological assessment difficult. New diagnostics and treatment modalities are urgently needed for these lymphomas, particularly in drug development for cancer-specific targets. Previously, we showed that a subset of B cell lymphoma, diffuse large B cell lymphoma, may be
American Society for Investigative Pathology.