Differential Expression
Mostrando 1-12 de 2993 artigos, teses e dissertações.
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1. UVB irradiation differential regulate miRNAs expression in skin photoaging
Abstract Background: UVB irradiation can cause acute damage such as sunburn, or photoaging and melanoma, all of which are major health threats. Objective: This study was designed to investigate the mechanism of skin photoaging induced by UVB radiation in mice through the analysis of the differential expression of miRNAs. Methods: A UVB irradiation photoag
Anais Brasileiros de Dermatologia. Publicado em: 2022
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2. Evaluation of the Rho-kinase gene expression and polymorphisms in adult patients with acute appendicitis: a differential impact of gender
SUMMARY OBJECTIVE: Acute appendicitis represents one of the most common causes of acute intra-abdominal emergencies worldwide. In this case-control study, we aimed to investigate associations of Rho-kinase gene expression and polymorphisms with acute appendicitis in a Turkish population. We also aimed to study the effects of gender on these parameters. MET
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Biomarker potential of hsa-miR-145-5p in peripheral whole blood of manic bipolar I patients
Objective: Bipolar I disorder (BD-I) is a type of bipolar spectrum disorder characterized by manic or mixed episodes. Detecting microRNA regulations as epigenetic actors in BD-I is important to elucidate the pathogenesis of the disease and reveal the potential of microRNAs (miRNAs) as biomarkers. Methods: We evaluated the expression profile of six candidate
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Downregulation of CSF-derived miRNAs miR-142-3p and miR-17-5p may be associated with post-dural puncture headache in pregnant women upon spinal anesthesia
Abstract Background: Postdural puncture headache (PDPH) develops due to puncture of the dura mater. The risk factors that influence PDPH incidence are Body Mass Index (BMI), sex, spinal needle type, history of headache, and loss of Cerebrospinal fluid (CSF) volume, yet there is no consensus on these risk factors. The pathophysiology of PDPH is poorly unders
Brazilian Journal of Anesthesiology. Publicado em: 2022
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5. Is serum PSA a predictor of male hypogonadism?
ABSTRACT Objective: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to cancer, their impact on its features, as well as the role of mRNA expression of these genes in thyroid malignancy
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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6. A fragilidade dos marcadores culturais nas comunidades acadêmicas: distanciamento físico e ofuscação dos referentes grupais
ABSTRACT Objective: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to cancer, their impact on its features, as well as the role of mRNA expression of these genes in thyroid malignancy
Rev. contab. finanç.. Publicado em: 2021-04
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7. Clinical utility of TGFB1 and its receptors (TGFBR1 and TGFBR2) in thyroid nodules: evaluation based on single nucleotide polymorphisms and mRNA analysis
ABSTRACT Objective: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to cancer, their impact on its features, as well as the role of mRNA expression of these genes in thyroid malignancy
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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8. Mapping Biochemical Pathways in Maytenus ilicifolia (Celastraceae) through Integrated Proteomics and Histochemistry
Maytenus ilicifolia (Celastraceae) is a medicinal plant that is native to southern Brazil and is popularly known as “espinheira-santa”. From a biosynthesis perspective, this species accumulates quinonemethide triterpenes and sesquiterpene pyridine alkaloids as major secondary metabolites that exhibit interesting biological properties, with antitumoral an
J. Braz. Chem. Soc.. Publicado em: 2021-02
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9. Differential gene expression of pectin esterase and changes in pectin during development and ripening stages of fruit in selected cultivars of banana
Abstract Pectin is a very important ingredient in food processing. The present study was designed to find out the changes taken place in pectin content during development and ripening phases of banana fruit. The expression of gene (pectin esterase) was also observed during development and ripening. Five exotic cultivars namely William, Brazilian, G-Naine, Ba
Food Sci. Technol. Publicado em: 2020-12
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10. METABOLÔMICA DE PLANTAS: MÉTODOS E DESAFIOS
Metabolomics has played a central role in various areas of plant sciences, offering new perspectives for the advancement of agriculture, drug discovery, chemical ecology and taxonomy. Plant metabolomics (identification and quantification) aims to understand the relationship between biological systems and genetic, pathological and or environmental stimuli in
Quím. Nova. Publicado em: 2020-03
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11. Standardization of organoid culture for evaluation of melanogenesis induced by UVB, UVA and visible light,
Abstract Background: Organoid cultures are primary cultures that maintain architectural characteristics and the relationships between cells, as well as the extracellular matrix. They are alternatives for pathophysiological or therapeutic investigation rather than animal and in vitro tests. Objective: Development of a cutaneous organoid culture model, aimin
An. Bras. Dermatol.. Publicado em: 2020-02
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12. Differential expression of T helper cytokines in the liver during early pregnancy in sheep
Abstract Liver plays important roles in the innate and adaptive immunity, and contributes to the maternal immune adjustments during pregnancy in mice and rats. T helper 1 (Th1) and Th2 cytokines are related to immune response. However, expression of Th1 and Th2 cytokines in maternal livers is unclear during early pregnancy in sheep. In this study, livers wer
Anim. Reprod.. Publicado em: 25/11/2019