Diethylcarbamazine
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. SIMPLE AND SELECTIVE SPECTROPHOTOMETRIC ASSAY OF DIETHYLCARBAMAZINE CITRATE USING 2,3-DICHLORO-5,6-DICYANO-
p -BENZOQUINONE AND 2,4-DINITRO PHENOLTwo simple, rapid and inexpensive spectrophotometric methods are described for the determination of diethylcarbamazine citrate (DEC) in bulk drug and formulations. The methods are based on the charge–transfer (CT) complexation reaction involving DEC as the n- donor and 2,3-dichloro-5,6-dicyano-
p -benzoquinone [DDQ] (method A) and 2,4-dinQuím. Nova. Publicado em: 2015-06
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2. Titrimetric and spectrophotometric assay of diethylcarbamazine citrate in formulations using iodate and iodide mixture as reagents
Propõem-se titulação e dois métodos espectrofotométricos para a determinação de citrato de dietilcarbamazina (DEC) a granel e em suas formulações, usando iodato de potássio e iodeto de potássio como reagente. Os métodos utilizam a reação analítica conhecida entre iodato e iodeto, na presença de ácido. Na titulometria (Método A), o fármaco
Braz. J. Pharm. Sci.. Publicado em: 2015-03
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3. Caracterização de estado sólido e análise computacional de uma nova forma cristalina do fármaco antifilariose dietilcarbamazina: um sal de ácido maleico / Characterization of solid state and computational analysis of a new crystalline form of the antifilarial drug diethylcarbamazine: a maleic acid salt
A caracterização no estado sólido de insumos farmacêuticos constitui uma parte muito importante no entendimento de suas propriedades físicas, químicas e farmacológicas. A partir da análise estrutural por difração de raios X em monocristal, pode-se identificar a conformação no estado sólido do fármaco, assim como sua densidade eletrônica. Estes
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/08/2011
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4. Influence of anti-filarial chemotherapy strategies on the genetic structure of Wuchereria bancrofti populations
Lymphatic filarial (LF) parasites have been under anti-filarial drug pressure for more than half a century. Currently, annual mass drug administration (MDA) of diethylcarbamazine (DEC) or ivermectin in combination with albendazole (ALB) have been used globally to eliminate LF. Long-term chemotherapies exert significant pressure on the genetic structure of pa
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-03
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5. Polimorfismo em fÃrmacos / Polymorphism in Drugs
O polimorfismo à a habilidade de um material existir em mais de uma forma cristalina. à bem estabelecido que os fÃrmacos podem existir em diversas formas polimÃrficas e estas propriedades possuem um impacto na qualidade/desempenho dos medicamentos, tais como a estabilidade quÃmica, a dissoluÃÃo e a biodisponibilidade. A proposta desse trabalho foi rea
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/08/2009
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6. Diethylcarbamazine citrate, an antifilarial drug, stimulates human granulocyte adherence.
Incubation with diethylcarbamazine citrate caused significant augmentation of human neutrophil and eosinophil adherence to tissue culture plastic. This effect was dose dependent and cell dependent, with eosinophils showing greater sensitivity and a greater adhesive response to the drug than did neutrophils. Eosinophils preincubated with diethylcarbamazine ci
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7. Pulmonary function in tropical eosinophilia before and after treatment with diethylcarbamazine.
Spirometric and lung volume measurements were carried out before and after treatment with diethylcarbamazine in 19 patients with tropical eosinophilia. The total lung capacity and vital capacity returned to or nearly to normal while the FEV1 and PEFR, though improved, tended to remain below normal, indicating some residual airways obstruction especially in p
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8. Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suramin.
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9. Comparative Effects of 3-Ethyl-8-Methyl-1,3,8-Triazabicyclo[4,4,0]Decan-2-one and Diethylcarbamazine Against Litomosoides carinii in Rodents
3-Ethyl-8-methyl-1,3,8-triazabicyclo[4,4,0]decan-2-one and diethylcarbamazine were tested comparatively against Litomosoides carinii in Mongolian jirds and cotton rats. The drugs were compared in jirds by oral and by intraperitoneal administration. Comparisons in cotton rats were done by intraperitoneal administration. The drugs were given in a wide range of
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10. Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C). In addition to the well recognised systemic reactions to treatment, the following ocular changes occurred during therapy: (1) Transient pigment epithelial lesions were detected in 7 patients by fluorescein angiogra
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11. Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.
Twenty men with moderate infection of Onchocerca volvulus were studied in a double-masked, controlled clinical trial to compare the safety and efficacy of oral diethylcarbamazine (DEC) with topical DEC lotion. Visual acuity and colour vision did not alter during the 6 months of observation, although 2 patients receiving DEC lotion and 3 patients receiving or
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12. Tolerability and efficacy of single dose albendazole, diethylcarbamazine citrate (DEC) or co-administration of albendazole with DEC in the clearance of Wuchereria bancrofti in asymptomatic microfilaraemic volunteers in Pondicherry, South India: a hospital-based study
BioMed Central.