Dicaffeoylquinic Acids
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Simultaneous HPTLC quantification of three caffeoylquinic acids in Pluchea indica leaves and their commercial products in Thailand
ABSTRACT In Thai traditional medicine, Pluchea indica (L.) Less., Asteraceae, leaf has been widely used for the treatment of diabetes mellitus, tumors, hypertension, cystitis, and wounds. P. indica herbal tea is commercially available in Thailand as a health-promoting drink. The study was conducted to develop and validate a high-performance thin-layer chroma
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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2. Optimization of extraction method and HPLC analysis of six caffeoylquinic acids in Pluchea indica leaves from different provenances in Thailand
ABSTRACT Pluchea indica (L.) Less., Asteraceae, is a medicinal plant which contains a high amount of phenolic compounds such as caffeoylquinic acid derivatives. The leaves have been traditionally used as a nerve tonic and extensively as herbal tea. This study aimed to develop and validate an HPLC method to quantitatively analyze six caffeoylquinic acid deriv
Rev. bras. farmacogn.. Publicado em: 2018-04
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3. Óleos essenciais e compostos fenólicos de espécimes masculinos e femininos de Baccharis uncinella DC
This study aimed to: develop methodological sequences for the collection and analysis of essential oils and phenolic compounds of B. uncinella, applicable to the study of other species of the genus Baccharis; determined by techniques of gas chromatography-mass spectrometry, the chemical composition of essential oils from the leaves of male and female specime
Publicado em: 2010
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4. HPLC-ESI-MS/MS analysis of oxidized di-caffeoylquinic acids generated by metalloporphyrin-catalyzed reactions
This paper reports an HPLC-ESI-MS/MS investigation on the oxidation of 3,5- and 4,5- dicaffeoylquinic acid using iron(III) tetraphenylporphyrin chloride as catalyst. Two major mono-oxidised products of the quinic acid moiety have been identified for both compounds. However, only the 4,5-derivative afforded two different tri-oxo products. Thus, it seems that
Química Nova. Publicado em: 2008
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5. Lychnophora ericoides Mart: pharmacological evaluation and considerations on the oxidative metabolism from its bioactive compounds / Lychnophora ericoidesMart: avaliação farmacológica e considerações sobre o metabolismo oxidativo das substâncias bioativas
The scientific study of medicinal plants is a multidisciplinary task and involves many fields of knowledge such as physics, chemistry and biology. In this context, pharmacological and toxicological studies play an important role since they allow evaluating parameters such as safety and efficacy. These parameters have to be well established, being essential f
Publicado em: 2006
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6. Inhibitors of HIV-1 replication that inhibit HIV integrase.
HIV-1 replication depends on the viral enzyme integrase that mediates integration of a DNA copy of the virus into the host cell genome. This enzyme represents a novel target to which antiviral agents might be directed. Three compounds, 3,5-dicaffeoylquinic acid, 1-methoxyoxalyl-3,5-dicaffeoylquinic acid, and L-chicoric acid, inhibit HIV-1 integrase in bioche
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7. Dicaffeoylquinic and Dicaffeoyltartaric Acids Are Selective Inhibitors of Human Immunodeficiency Virus Type 1 Integrase
Current pharmacological agents for human immunodeficiency virus (HIV) infection include drugs targeted against HIV reverse transcriptase and HIV protease. An understudied therapeutic target is HIV integrase, an essential enzyme that mediates integration of the HIV genome into the host chromosome. The dicaffeoylquinic acids (DCQAs) and the dicaffeoyltartaric
American Society for Microbiology.
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8. Irreversible Inhibition of Human Immunodeficiency Virus Type 1 Integrase by Dicaffeoylquinic Acids†
Human immunodeficiency virus type 1 (HIV-1) and other retroviruses require integration of a double-stranded DNA copy of the RNA genome into the host cell chromosome for productive infection. The viral enzyme, integrase, catalyzes the integration of retroviral DNA and represents an attractive target for developing antiretroviral agents. We identified several
American Society for Microbiology.
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9. Studies on Chlorogenic Acid Biosynthesis in Sweet Potato Root Tissue in Special Reference to the Isolation of a Chlorogenic Acid Intermediate 1
Marked polyphenol production takes place in root tissue of sweet potato, Ipomoea batatas Lam. cv. Norin 1, in response to slicing. A possible intermediate, tentatively termed compound V, of chlorogenic acid biosynthesis was isolated from the root tissue administrated with t-cinnamic acid-2-14C. Compound V was proved to be an ester whose acid moiety was t-cin