Depressive Disorder
Mostrando 1-12 de 276 artigos, teses e dissertações.
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1. O transtorno depressivo pode ser geneticamente herdado?
Sobre os fatores genéticos da depressão, a herdabilidade da depressão ainda não é consenso na literatura cientifica. No entanto, segundo alguns estudos estima-se que 37% dos casos possam ter uma relação genética, mesmo que essas relações sejam posteriormente moduladas pelo ambiente – ou seja, embora os genes possam ser relevantes para o surgim
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
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2. Heterozygosity for neuronal ceroid lipofuscinosis predisposes to bipolar disorder
Objective: Bipolar disorder is a heritable chronic mental disorder that causes psychosocial impairment through depressive/manic episodes. Familial transmission of bipolar disorder does not follow simple Mendelian patterns of inheritance. The aim of this study was to describe a large family with 12 members affected by bipolar disorder. Whole-exome sequencing
Brazilian Journal of Psychiatry. Publicado em: 2023
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3. Immature defense mechanisms predict poor response to psychotherapy in major depressive patients with comorbid cluster B personality disorder
Objective: To evaluate the impact of defense mechanisms at baseline on depressive symptoms after brief psychotherapies and after 6-months of follow-up among depressed patients with and without cluster B personality disorders (PDs). Methods: This quasi-experimental study nested within a randomized clinical trial included a clinical sample of adults (18-60 ye
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Evening chronotype as a bipolar feature among patients with major depressive disorder: the results of a pilot factor analysis
Objectives: The bipolar spectrum concept has resulted in a paradigm shift that has affected both the diagnosis and therapy of mood disorders, with bipolarity becoming an indicator of treatment resistance in depression. Evening circadian preference has also been linked to affective disorders. The aim of our study was to confirm the relationship between the se
Brazilian Journal of Psychiatry. Publicado em: 2022
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5. Binge eating disorder, frequency of depression, and systemic inflammatory state in individuals with obesity – A cross sectional study
ABSTRACT Objective: Binge eating disorder (BED) is the most prevalent eating disorder in individuals with obesity. Its association with factors that control hunger and satiety has not yet been elucidated. We evaluated whether levels of inflammatory markers, frequency of psychiatric comorbidities, and appetite-related hormones levels differ between individua
Archives of Endocrinology and Metabolism. Publicado em: 2022
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6. Epidemiological profile of suicide attempts in a municipality in southwest Paraná, from 2017 to 2020
SUMMARY OBJECTIVE: This study aimed to analyze the epidemiological profile and psychological disorder of the suicide attempt cases in Francisco Beltrão, Paraná. METHODS: This is an epidemiological descriptive/qualitative study of suicide attempts conducted between 2017 and 2020. This study used data from the Brazilian Information system for notifications
Revista da Associação Médica Brasileira. Publicado em: 2022
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7. Distractibility, anxiety, irritability, and agitation symptoms are associated with the severity of depressive and manic symptoms in mixed depression
Objective: To explore whether there is an association between distractibility, anxiety, irritability, and agitation (DAIA) symptoms and the severity of depressive and manic symptoms. Methods: Patients with unipolar and bipolar disorder (I and II) and mixed depression were evaluated. DAIA symptoms were assessed using previously described definitions. Result
Brazilian Journal of Psychiatry. Publicado em: 2022
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8. Low-dose ketamine does not improve the speed of recovery from depression in electroconvulsive therapy: a randomized controlled trial
Objective: Electroconvulsive therapy (ECT) is a well-established therapeutic intervention for major depressive disorder. Recent literature has shown that the anesthetic agent ketamine has some antidepressant properties at low doses and may be an alternative therapy for treatment-resistant major depressive disorder. We hypothesized that the use of low-dose ke
Brazilian Journal of Psychiatry. Publicado em: 2022
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9. Comorbidity of psychiatric and dermatologic disorders with skin picking disorder and validation of the Skin Picking Scale Revised for Brazilian Portuguese
Objective: Skin picking disorder (SPD) affects up to 5.4% of the population. Less than half of patients are correctly diagnosed and treated. Developing tools to recognize SPD can help professionals and patients alike. This trial aimed to validate the Skin Picking Scale-Revised (SPS-R) for the Brazilian population and assess the psychiatric and dermatological
Brazilian Journal of Psychiatry. Publicado em: 2022
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10. Clinico-epidemiological profile of patients at children’s psychosocial care centers in São Bernardo do Campo: a cross-sectional study
ABSTRACT BACKGROUDS: Child and Adolescent Psychosocial Care Centers (Centros de Atenção Psicossocial, CAPSI) are dedicated centers for persistent psychiatric disorders, which provide an individualized therapeutic approach based on extra-hospital services. OBJECTIVES: We aimed to describe the clinico-epidemiological profiles of the patients seeking interv
Sao Paulo Medical Journal. Publicado em: 2022
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11. Adolescent depression and resting-state fMRI brain networks: a scoping review of longitudinal studies
The neurobiological factors associated with the emergence of major depressive disorder (MDD) in adolescence are still unclear. Previous cross-sectional studies have documented aberrant connectivity in resting-state functional magnetic resonance imaging (rs-fMRI) networks. However, whether these findings precede MDD onset has not been established. This scopin
Brazilian Journal of Psychiatry. Publicado em: 2022
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12. Does mismatch negativity have utility for NMDA receptor drug development in depression?
Rapid antidepressant effects associated with ketamine have shifted the landscape for the development of therapeutics to treat major depressive disorder (MDD) from a monoaminergic to glutamatergic model. Treatment with ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, may be effective, but has many non-glutamatergic targets, and clinical and logis
Brazilian Journal of Psychiatry. Publicado em: 2022