Depletion
Mostrando 1-12 de 4051 artigos, teses e dissertações.
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1. A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans
Abstract XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we create a germline-specific xrn-2 conditional mutant and p
Genetics and Molecular Biology. Publicado em: 2023
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2. Collection, cryopreservation and thawing of stem cells for children weighing less than 25 Kg with high-risk neuroblastoma: A single center results in Morocco
ABSTRACT Introduction: An important component of the advances made in neuroblastoma treatment has been the use of peripheral blood stem cells to support high-dose chemotherapy. In this study, we report our experience on a series of small children who have undergone standard and large volume leukaphersis (LVL) procedures, provide an update on a single instit
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. Nasal Mucociliary Clearance in Smokers: A Systematic Review
Abstract Introduction Smoking is one of the most important causes of mortality and morbidity in the world, as it is related to the risk factor and etiology of respiratory-tract diseases. Long-term smoking causes both structural and functional damage in the respiratory airways, leading to changes in nasal mucociliary clearance (NMC). Objectives The aim of t
Int. Arch. Otorhinolaryngol.. Publicado em: 2021-01
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4. Is there a role for sacral neuromodulation in patients with neurogenic lower urinary tract dysfunction?
ABSTRACT Purpose To review current literature regarding sacral neuromodulation (SNM) for neurogenic lower urinary tract dysfunction (NLUTD) focused on indications, barriers and latest technological developments. Material and Methods A PubMed database search was performed in April 2020, focusing on SNM and various neuro-urological conditions. Results SN
Int. braz j urol.. Publicado em: 2020-12
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5. Rhizobium rhizogenes-mediated transformation of Rhodiola rosea leaf explants
ABSTRACT Rhodiola rosea L. is an endangered medicinal plant distributed in mountains and in high latitude regions. For its conservation, sustainable methods for the obtaining of its bioactive compounds must be developed. This work hypothesized that leaf, stem and rhizome explants of R. rosea from different geographical origins respond differently to inoculat
Bragantia. Publicado em: 2020-06
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6. Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
ABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a t
Sao Paulo Med. J.. Publicado em: 2020-03
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7. lncRNA OIP5-AS1 targets ROCK1 to promote cell proliferation and inhibit cell apoptosis through a mechanism involving miR-143-3p in cervical cancer
Opa-interacting protein 5 antisense transcript 1 (OIP5-AS1) is one kind of cytoplasmic long non-coding RNA (lncRNA), which has been demonstrated to play a critical function in multiple cancers. However, the detailed mechanism of OIP5-AS1 in the regulation of cervical cancer progression is still obscure. Here, we demonstrated that lncRNA OIP5-AS1 was upregula
Braz J Med Biol Res. Publicado em: 2020-01
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8. Persistent double strand break accumulation does not precede cell death in an Olaparib-sensitive BRCA-deficient colorectal cancer cell model
Abstract The poly (adenosine diphosphate (ADP)-ribosyl) polymerase inhibitors (PARPi) selectively kill cancer cells with BRCA1 or BRCA2 (BRCA)-mutations. It has been proposed that cell death induction after PARPi depends on unrepaired double strand breaks (DSBs) that accumulate due to the homologous recombination deficiency of BRCA-mutated cells. Such accumu
Genet. Mol. Biol.. Publicado em: 13/12/2019
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9. Samsum ant venom modulates the immune response and redox status at the acute toxic dose in vivo
Abstract Background: Ant venoms express surface molecules that participate in antigen presentation involving pro- and anti-inflammatory cytokines. This work aims to investigate the expression of MHC-II, CD80 and CD86 on the polymorphonuclear cells (PMNs) in rats injected with samsum ant venom (SAV). Methods: Rats were divided into three groups - control,
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/12/2019
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10. The variability of the subantarctic front and the Southern Hemisphere atmospheric jet
Abstract The latitudinal variations of the Subantarctic Front (SAF) and Southern Hemisphere atmospheric jet were investigated for the period of 1993-2016. Zonal wind velocity, sea surface height and temperature data were used to identify these features over the South Atlantic, South Pacific and Indian Oceans individually. During this period, the atmospheric
Braz. j. oceanogr.. Publicado em: 02/12/2019
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11. Natural abundance of 15N of N derived from the atmosphere by different strains of Bradyrhizobium in symbiosis with soybean plants
RESUMO: Para quantificar a FBN em leguminosas, através da técnica de abundância natural de 15N, é importante conhecer a abundância de 15N da planta leguminosa crescida inteiramente dependente da FBN (valor ‘B’). O objetivo deste estudo foi determinar a abundância natural de 15N do N2 fixado por diferentes estirpes de Bradyrhizobium em simbiose com
Cienc. Rural. Publicado em: 25/11/2019
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12. Avaliação do ciclo de vida da coleta seletiva de papel e papelão no núcleo do Bessa, município de João Pessoa (PB), Brasil
RESUMO Reconhecendo que o papel e o papelão são os materiais mais identificados na gestão dos resíduos sólidos domiciliares (RSD), o objetivo deste artigo foi aplicar a metodologia da Avaliação de Ciclo de Vida (ACV) aos procedimentos de coleta seletiva desses materiais em um núcleo de João Pessoa (PB). A ACV quantifica as cargas ambientais ao longo
Eng. Sanit. Ambient.. Publicado em: 25/11/2019