Defined Daily Dose
Mostrando 13-24 de 41 artigos, teses e dissertações.
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13. Use of antibacterial agents in an intensive care unit in a hospital in Brazil
It is essential to monitor the utilisation of antibacterial drugs in order to establish appropriate measures for their control. The pattern of usage of antibacterial drugs, and its association with indicators of hospital infection, has been investigated in a non-specialized adult intensive care unit (ICU) located in Santa Luzia Hospital (Brasília, DF, Brazi
Brazilian Journal of Infectious Diseases. Publicado em: 2007-06
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14. Padrões de utilização de antibacterianos em três unidades de terapia intensiva do Distrito Federal
To know the patterns of use of antibacterial agents in the intensive care units (ICU) of the Federal District have been conducted two studies. The first study was retrospective and it was done in a private hospital, from January 2001 to June 2004. There used aggregate data from the electronic files of the hospital pharmacy and all 2890 patients admitted to t
Publicado em: 2007
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15. Uso do laser de baixa intensidade (GaAlAs) na prevenção de mucosite bucal em pacientes submetidos a transplante de medula óssea / Use of low intensity laser (GaAlAs) in the prevention of oral mucositis in patients undergoing bone marrow transplantation
Oral mucositis is one of the most debilitating complications in patients undergoing bone marrow transplants, occurring 50 to100% in these patients. The oral mucositis treatment and prevention is not completely defined, although the low intensity laser is widely used. The aim of the current study was to investigate the use of low intensity laser (GaAlAs) in t
Publicado em: 2006
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16. Antibiotic prophylaxis in orthopedic surgeries: the results of an implemented protocol
Though the basic principles of antibiotic prophylaxis have been well established, there is still considerable incorrect usage, including how much is prescribed and especially in the duration of treatment, which is generally superior to what is indicated. The adequate use of these drugs contributes towards decreasing the time of internment of the patient, pre
Brazilian Journal of Infectious Diseases. Publicado em: 2005-08
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17. Avaliação das concentrações hepáticas e séricas de retinol em bovinos e do consumo habitual de fígado por gestantes
The vitamin A is essential to animals because of its participation in a great number of biological functions. The investigation of this vitamins concentrations is important to serve as reference to normality parameters. This study had as aim to analyse the serics and hepatics concentrations of vitamin A in two groups of bovines and to compare the hepatics co
Publicado em: 2005
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18. Factibilidade do uso do cateter tipo Hickman em uma enfermaria geral de hematologia
Central venous catheters (CVCs) are essential for patients undergoing autologous bone marrow transplantation (ABMT). Hickman s catheter (HC) is a long-term, tunneled and cuffed venous access. This type of catheter constitutes a safe and useful line for administration of chemotherapy, antimicrobial agents, blood products, hydration, total parenteral nutrition
Publicado em: 2005
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19. Operacionalizando conceitos em farmacoepidemiologia : estudos de utilização de medicamentos e de farmacovigilancia
BACKGROUND: In all phases of the process of development of a new medicine the drug safety and the profile of adverse drug reactions it is always object of a lot of attention. Though, even with all the methodological concerns, when a drug goes to the postmarketing phase, a small number of patients were exposed indeed to the new drug. Pharmacoepidemiology uses
Publicado em: 2004
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20. Characteristics of HIV antiretroviral regimen and treatment adherence
The relationship between characteristics of HIV antiretroviral regimens and treatment adherence was studied in adolescent and adult patients who underwent antiretroviral therapy from January 1998 to September 2000, at the Service for Specialized Assistance in Pelotas. The patients were interviewed on two occasions, and the use of antiretrovirals during the p
Brazilian Journal of Infectious Diseases. Publicado em: 2003-06
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21. Estudos de aspectos psicologicos e culturais de familiares de um grupo de pacientes esquizofrenicos frente a doença
Aims: General: The general aim was to assess and discuss elements related to the informatio~ attitudes and beliefs on schizophrenia among 11 family members of patients at UNICAMP. The specific aims were: a) to assess if the family members had been adequately informed on nosological diagnostic and possible ethiology, course, therapeutics and prognosis; b) to
Publicado em: 1998
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22. A new approach to evaluating carcinogenic risk.
Carcinogenic risk assessments are based on extrapolating from high-dose chronic rodent-feeding studies to human-exposure levels. A serious problem is that about half of all substances tested at their respective maximum tolerated dose (MTD) are found to induce cancer. The MTD as currently defined has been criticized because it may stimulate cell proliferation
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23. Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding.
The relative importance of pharmacokinetic and pharmacodynamic parameters for the feasibility of a single daily dose (SDD) of antibiotics remains to be established. Therefore, we studied the relationship between in vitro bacteriological parameters (MIC, MBC, and killing rate [KR], defined as the reduction in the inoculum within 3 h), pharmacokinetic paramete
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24. Pharmacokinetic and Pharmacodynamic Study of the Human Immunodeficiency Virus Protease Inhibitor Amprenavir after Multiple Oral Dosing
In a dose-ranging study of amprenavir (formerly 141W94), an inhibitor of the protease enzyme of human immunodeficiency virus (HIV) type 1, single-dose and steady-state pharmacokinetic parameters were estimated from plasma samples collected on day 1 and during week 3, respectively. Amprenavir was administered on either a twice-daily (b.i.d.) or three-times-da
American Society for Microbiology.