Dctn
Mostrando 13-14 de 14 artigos, teses e dissertações.
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13. Characterization of DCTN1 genetic variability in neurodegeneration
American Academy of Neurology.
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14. Functionally distinct isoforms of dynactin are expressed in human neurons.
P150Glued is the largest subunit of dynactin, which binds to cytoplasmic dynein and activates vesicle transport along microtubules. We have isolated human cDNAs encoding p150Glued as well as a 135-kDa isoform; these isoforms are expressed in human brain by alternative mRNA splicing of the human DCTN1 gene. The p135 isoform lacks the consensus microtubule-bin