Database Fragmentation
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Galanthamine and other Amaryllidaceae related alkaloids are inhibitors of α7, α4β2 and α3β4 nicotinic acetylcholine receptors
Abstract Galanthamine is an Amaryllidaceae-derived acetylcholinesterase inhibitor used to treat memory impairment in Alzheimer's disease and vascular dementia. There is evidence that galanthamine, in addition to its effects on acetylcholinesterase, may enhance or inhibit brain nicotinic acetylcholine receptors, which could increase or decrease the therapeuti
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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2. Rhodolirium andicola: a new renewable source of alkaloids with acetylcholinesterase inhibitory activity, a study from nature to molecular docking
ABSTRACT Acetylcholinesterase is an important target for control of neurodegenerative diseases causing cholinergic signaling deficit. Traditionally, galanthamine has been used as an Amaryllidaceae-derived acetylcholinesterase inhibitor, although new Amaryllidaceae plants could serve as source for better acetylcholinesterase inhibitors. Therefore, the objecti
Rev. bras. farmacogn.. Publicado em: 2018-01
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3. A relevância das unidades de conservação na proteção de espécies arbóreas ameaçadas de extinção da Mata Atlântica do Sudeste da Bahia / The relevance of conservation units for the protection of tree species threatened by extinction from Atlantic Forest of Southeast of Bahia
A Floresta Atlântica do sudeste da Bahia apresenta uma das maiores riquezas de espécies arbóreas por área do planeta, com uma significativa porcentagem endêmica. Essas espécies encontram-se altamente ameaçadas pelos elevados índices de desmatamento, fragmentação de habitat e corte seletivo decorrente na região. As Unidades de Conservação têm ,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2011
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4. Fragmentação e decomposição de consultas em XML / Fragmentation and query decomposition in XML
O problema da integração de dados (fragmentação de dados, decomposição de consultas) tem sido largamente estudado na literatura, mas a estrutura hierárquica inerente do modelo XML apresenta problemas que são específicos deste modelo de dados. Cada relacionamento conceitual muitos-para-muitos deve ser mapeado para uma estrutura hierárquica específi
Publicado em: 2007
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5. RECRIAÇÃO AUTOMÁTICA DE ÍNDICES EM UM SGBD RELACIONAL / AUTOMATIC REINDEXING IN RELATIONAL DATABASES
One of the most important tasks of Database Administrators certainly is to guarantee optimal response times to statements submitted by users of big RDBMS. Our dissertation deals with Index Self-tuning, which means creating, dropping or recreating indexes automatically, in order to decrease SQL queries durations. We start from Marcos Salles´ dissertation [32
Publicado em: 2006
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6. Uma abordagem proteomica na identificação do citocromo P450 em Prochilodus Scrofa : uma nova ferramenta em ensaios ecotoxicologicos
Cytochromes P450 constitute a superfamily of the phase I enzymes whose primary task is the detoxification of both endogenous and xenobiotic compounds. This activity is only possible through the association of CYP with cytochrome b5 and the enzyme NADPH cytochrome P450 reductase. This association is possible because of membrane environment. Any alteration in
Publicado em: 2004
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7. Dinâmica da paisagem na região nordeste do estado do Rio Grande do Sul.
Environmental analysis and land use dynamics of the landscape northwest area of the Rio Grande do Sul Province. With the growing demand for natural resources the environmental analysis and the periodic diagnosis of the land use started to represent a fundamental aspect for the understanding of the occupation patterns and spatial organization of the landscape
Publicado em: 2003
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8. DistribuiÃÃo dos Dados em Ambientes de Data Warehousing: O Sistema WebD2W e Algoritmos Voltados à FragmentaÃÃo Horizontal dos Dados
A data warehousing environment consolidates data of interest from distributed, autonomous and heterogeneous information sources into a single database, called as data warehouse. This environment guarantees efficiency and flexibility in the recovery of strategic information turned to management and decision-making processes, and maintains integrated data in t
Publicado em: 2002
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9. ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry
ProSight PTM (https://prosightptm.scs.uiuc.edu/) is a web application for identification and characterization of proteins using mass spectra data from ‘top-down’ fragmentation of intact protein ions (i.e. without any tryptic digestion). ProSight PTM has many tools and graphical features to facilitate analysis of single proteins, proteins in mixtures and
Oxford University Press.
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10. A method for high-sensitivity peptide sequencing using postsource decay matrix-assisted laser desorption ionization mass spectrometry
A method has been developed for de novo peptide sequencing using matrix-assisted laser desorption ionization mass spectrometry. This method will facilitate biological studies that require rapid determination of peptide or protein sequences, e.g., determination of posttranslational modifications, identification of active compounds isolated from combinatorial
The National Academy of Sciences.
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11. trEST, trGEN and Hits: access to databases of predicted protein sequences
High throughput genome (HTG) and expressed sequence tag (EST) sequences are currently the most abundant nucleotide sequence classes in the public database. The large volume, high degree of fragmentation and lack of gene structure annotations prevent efficient and effective searches of HTG and EST data for protein sequence homologies by standard search m
Oxford University Press.
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12. Identification of Fur, Aconitase, and Other Proteins Expressed by Mycobacterium tuberculosis under Conditions of Low and High Concentrations of Iron by Combined Two-Dimensional Gel Electrophoresis and Mass Spectrometry
Iron plays a critical role in the pathophysiology of Mycobacterium tuberculosis. To gain a better understanding of iron regulation by this organism, we have used two-dimensional (2-D) gel electrophoresis, mass spectrometry, and database searching to study protein expression in M. tuberculosis under conditions of high and low iron concentration. Proteins in c
American Society for Microbiology.