Damage Repair
Mostrando 13-24 de 1613 artigos, teses e dissertações.
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13. Analysis of radioprotection and antimutagenic effects of Ilex paraguariensis infusion and its component rutin
DNA repair pathways, cell cycle checkpoints, and redox protection systems are essential factors for securing genomic stability. The aim of the present study was to analyze the effect of Ilex paraguariensis (Ip) infusion and one of its polyphenolic components rutin on cellular and molecular damage induced by ionizing radiation. Ip is a beverage drank by most
Braz J Med Biol Res. Publicado em: 16/07/2018
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14. Pelletizing furnace refractory lining life cycle extension by applying thermography analysis and direct refractory injection
Abstract The induration furnace is one of the most important devices in the pellet production system. It is responsible for ensuring the quality of pellets produced, since a high level of thermal energy is necessary to reach the physical properties needed. Therefore, the refractory lining performance is important to guarantee the quality of pellets and to av
REM, Int. Eng. J.. Publicado em: 2018-07
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15. XRCC4 rs6869366 polymorphism is associated with susceptibility to both nicotine dependence and/or schizophrenia
Abstract Background: Oxidative stress induced DNA damage has been assumed to contribute to the etiopathogenesis of schizophrenia (Sch). Smoking prevalence was more common in patients with Sch. The X-ray repair cross-complementation group 4 (XRCC4) gene plays an important role in the repair of DNA double-strand breaks. Objective: The purpose of this study w
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2018-05
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16. Sensory-motor training versus resistance training among patients with knee osteoarthritis: randomized single-blind controlled trial
ABSTRACT BACKGROUND: Osteoarthritis of the knee is defined as a progressive disease of the synovial joints and is characterized by failure of joint damage repair. The objective here was to compare the effectiveness of sensory-motor training versus resistance training among patients with knee osteoarthritis. DESIGN AND SETTING: Randomized, single-blinded
Sao Paulo Med. J.. Publicado em: 07/12/2017
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17. Radiation Exposure in Endovascular Infra-Renal Aortic Aneurysm Repair and Factors that Influence It
Abstract Objective: The endovascular repair of aortic abdominal aneurysms exposes the patients and surgical team to ionizing radiation with risk of direct tissue damage and induction of gene mutation. This study aims to describe our standard of radiation exposure in endovascular aortic aneurysm repair and the factors that influence it. Methods: Retrospecti
Braz. J. Cardiovasc. Surg.. Publicado em: 2016-12
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18. Repairing of an Engine Block Through the Cold Gas Dynamic Spray Technology
In the modern automotive industry, the maintenance of the vehicle during its life cycle is increasing in importance due to both economical and environmental considerations. A new frontier is the reparation of large parts, originally made by fusion, by the addition of material. The standard technique in the field is the use of TIG welding, but in the last few
Mat. Res.. Publicado em: 26/09/2016
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19. DNA damage protective effect of honey-sweetened cashew apple nectar in Drosophila melanogaster
Abstract Fruits and derivatives, such as juices, are complex mixtures of chemicals, some of which may have mutagenic and/or carcinogenic potential, while others may have antimutagenic and/or anticancer activities. The modulating effects of honey-sweetened cashew apple nectar (HSCAN), on somatic mutation and recombination induced by ethyl methanesulfonate (EM
Genet. Mol. Biol.. Publicado em: 25/07/2016
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20. Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents
During its life cycle Leishmania spp. face several stress conditions that can cause DNA damages. Base Excision Repair plays an important role in DNA maintenance and it is one of the most conserved mechanisms in all living organisms. DNA repair in trypanosomatids has been reported only for Old World Leishmania species. Here the AP endonuclease from Leishmania
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-05
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21. Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
Abstract Breast cancer is the most common malignancy in women. Radiotherapy is frequently used in patients with breast cancer, but some patients may be more susceptible to ionizing radiation, and increased exposure to radiation sources may be associated to radiation adverse events. This susceptibility may be related to deficiencies in DNA repair mechanisms t
Genet. Mol. Biol.. Publicado em: 24/11/2015
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22. Occupational exposure of workers to pesticides: Toxicogenetics and susceptibility gene polymorphisms
Farm workers are often exposed to pesticides, which are products belonging to a specific chemical group that affects the health of agricultural workers and is mostly recognized as genotoxic and carcinogenic. The exposure of workers from Piauí, Brazil, to these hazardous chemicals was assessed and cytogenetic alterations were evaluated using the buccal micro
Genet. Mol. Biol.. Publicado em: 2015-09
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23. The effect of elemene on lung adenocarcinoma A549 cell radiosensitivity and elucidation of its mechanism
OBJECTIVE:To investigate the effect of elemene on the radiosensitivity of A549 cells and its possible molecular mechanism.METHODS:Apoptosis of A549 cells was detected by flow cytometry and fluorescence microscopy. The effect of double-strand break (DSB) damage repair in A549 cells was evaluated using the neutral comet assay. Protein expression levels were de
Clinics. Publicado em: 2015-08
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24. Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury
OBJECTIVES: Prevention of the development of paraplegia during the repair of the damage caused by descending thoracic and thoracoabdominal aneurysms remains an important issue. Therefore, we investigated the protective effect of atorvastatin on ischemia-induced spinal cord injury in a rabbit model. METHOD: Thirty-two rabbits were divided into the following
Clinics. Publicado em: 2015-01