Cytokines Immunology
Mostrando 25-34 de 34 artigos, teses e dissertações.
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25. Resposta imune celular a diferentes antígenos micobacterianos em indivíduos infectados por Mycobacterium tuberculosis: avaliação por elispot, elisa e linfoproliferação / .....
A tuberculose é uma doença crônica granulomatosa caracterizada por um déficit de imunidade antígeno específica do hospedeiro, cuja resposta imune é ativamente regulada por citocinas. No Brasil há mais de 50 milhões de habitantes infectados pelo Mycobacterium tuberculosis. O objetivo foi avaliar a linfoproliferação e a produção de citocinas por c
Publicado em: 2005
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26. Effect of Toxoplasma gondii infection on immune related tissue gene expression in pigs / Efeito da infecção pelo Toxoplasma gondii na expressão de genes associados à resposta imune em tecidos de suínos
Toxoplasmosis is a widespread zoonosis affecting humans and large range of animal species worldwide. Serological surveillance indicates high infection rates, but rarely is associated to severe disease. T. gondii (Tg) infection induces a strong IFN-γ dominated immune response that rapidly controls parasite replication. Pig resistance to toxoplasmosis was
Publicado em: 2004
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27. Avian cytokines in health and disease
Cytokines are proteins secreted by cells that play an important role in the activation and regulation of other cells and tissues during inflammation and immune responses. Although well described in several mammalian species, the role of cytokines and other related proteins is poorly understood in avian species. Recent advances in avian genetics and immunolog
Revista Brasileira de Ciência Avícola. Publicado em: 2003-04
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28. Mononuclear cells from umbilical cord blood and from granulocyte colony-stimulating factor (G-CSF) mobilized peripheral blood. Analysis of proliferation and apoptosis in vitro / "Células mononucleares de sangue de cordão umbilical e de sangue periférico estimulado com fator de crescimento granulocítico (G-CSF) : análise da proliferação e de apoptose in vitro"
Células mononucleares de sangue de cordão umbilical (SCU) e sangue periférico mobilizado (SPM) com G-CSF, foram cultivadas in vitro com citocinas, na presença ou não de estroma de medula óssea. Os objetivos foram avaliar a capacidade proliferativa de células progenitoras, a ocorrência de apoptose e expressão de integrina. Nas culturas sem estroma, a
Publicado em: 2003
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29. Immunology of term and preterm labor
During pregnancy there is an alteration in maternal immunity within the uterus where innate, proinflammatory immune responses are tightly regulated to prevent immunological rejection of the fetal allograft. Disruption of the delicate balance of cytokines by bacteria or other factors increases the production of proinflammatory cytokines at the maternal-fetal
BioMed Central.
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30. Cross-regulation of TNF and IFN-α in autoimmune diseases
Cytokines, most particularly TNF and type I IFN (IFN-αβ), have been long considered essential elements in the development of autoimmunity. Identification of TNF in the pathogenesis of rheumatoid arthritis and TNF antagonist therapy represent successes of immunology. IFN-αβ plays a major role in systemic lupus erythematosus (SLE), a prototype autoimmune d
National Academy of Sciences.
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31. Control of T helper 2 cell function and allergic airway inflammation by PKCζ
Asthma is a disease of chronic airway inflammation in which T helper (Th) 2 cells play a critical role. The molecular mechanisms controlling Th2 differentiation and function are of paramount importance in biology and immunology. PKCζ has been implicated in the regulation of apoptosis and NF-κB, as well as in the control of T-dependent responses, although n
National Academy of Sciences.
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32. Accelerated chemical synthesis of peptides and small proteins
The chemical synthesis of peptides and small proteins is a powerful complementary strategy to recombinant protein overexpression and is widely used in structural biology, immunology, protein engineering, and biomedical research. Despite considerable improvements in the fidelity of peptide chain assembly, side-chain protection, and postsynthesis analysis
The National Academy of Sciences.
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33. Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model
After encounter with Mycobacterium tuberculosis, a series of non-uniform immune responses are triggered that define the course of the infection. Eight M. tuberculosis strains were selected from a prospective population-based study of pulmonary tuberculosis patients (1995–2003) based on relevant clinical/epidemiological patterns and tested in a well-charact
Blackwell Science Inc.
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34. Differential Modulation of Surface and Intracellular Protein Expression by T Cells after Stimulation in the Presence of Monensin or Brefeldin A
Intracellular cytokine staining is an increasingly popular analytical tool that can be used to define the profile of cytokines in various disease states. One important requirement for this assay is the inclusion of a protein transport inhibitor in stimulated cell cultures to trap the cytokine, thus allowing a brighter signal. Two compounds commonly used for
American Society for Microbiology.