Cytogenetic
Mostrando 13-24 de 1110 artigos, teses e dissertações.
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13. Cytogenetic abnormalities, WHO classification, and evolution of children and adolescents with acute myeloid leukemia
ABSTRACT Objectives: To describe cytogenetic and molecular abnormalities observed in children and adolescents with acute myeloid leukemia (AML), classify AML according to the World Health Organization (WHO) classifications from 2008 and 2016, and evaluate the prognosis according to clinical characteristics and cytogenetic abnormalities. Methods: A retrospe
Hematol., Transfus. Cell Ther.. Publicado em: 10/10/2019
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14. What happens to intolerant, relapsed or refractory chronic myeloid leukemia patients without access to clinical trials?
ABSTRACT Objective: To assess clinical outcomes of intolerant, relapsed or refractory patients who could not be treated with new tyrosine kinase inhibitors or experimental therapies. Methods: A retrospective cohort of 90 chronic myeloid leukemia patients in all phases of the disease treated with imatinib mesylate as their first TKI therapy, and with dasati
Hematol., Transfus. Cell Ther.. Publicado em: 10/10/2019
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15. First chromosomal analysis of Gymnorhamphichthys britskii: the remarkable lowest diploid value within the family Rhamphichthyidae (Gymnotiformes)
RESUMO Gymnorhamphichthys britskii é um peixe neotropical da família Rhamphichthyidae descrita no sistema Paraná-Paraguai. Este estudo relata a primeira descrição cariotípica de G. britskii coletado na bacia do alto rio Paraná, que apresentou 2n = 38 cromossomos, cariótipo composto por 14 metacêntricos, 8 submetacêntricos, 2 subtelocêntricos e 14
Neotrop. ichthyol.. Publicado em: 30/09/2019
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16. Cytogenetic markers as tools in delimiting species of the highly diverse Neotropical fish Bryconamericus (Characiformes: Characidae)
RESUMO Bryconamericus é um grupo altamente diverso de caracídeos, sendo a citogenética uma valiosa ferramenta para a delimitação de espécies. Bryconamericus aff. iheringii (Alto Uruguai/Baixo Paraná), B. coeruleus (Alto Paraná), B. cf. ecai e B. cf. eigenmanni (Alto Uruguai) foram estudados citogeneticamente, e apresentaram 2n=52 cromossomos, com var
Neotrop. ichthyol.. Publicado em: 23/09/2019
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17. [PROVISIONAL] Non-mosaic partial duplication 12p in a patient with dysmorphic characteristics and developmental delay
Abstract Duplication of the short arm of chromosome 12 is a rare chromosomal abnormality that may arise de novo or result from malsegregation of a balanced parental translocation. This study comprises the clinical description, cytogenetic and cytogenomic analyses and genotype-phenotype correlation in a patient with facial dysmorphism, developmental delay and
Genet. Mol. Biol.. Publicado em: 19/08/2019
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18. Cytogenetic studies in three diploid species of Andropogon (Andropogoneae), section Leptopogon
Abstract Karyotypes can provide a relevant information about relationships and evolutionary origin among species of the Andropogon genus. This paper presents the karyotype, C+ and DAPI/CMA3 banding and DNA content of three diploid (2n=20) species belonging to section Leptopogon: A. selloanus, A. macrothrix and A. gyrans. Karyotypes of the three diploid speci
Rodriguésia. Publicado em: 08/08/2019
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19. Cytogenetics and DNA barcode reveal an undescribed Apareiodon species (Characiformes: Parodontidae)
Abstract Parodontidae is a small group of fish and some species are particularly difficult to identify due to the lack of sufficiently consistent morphological traits. Cytogenetically, the species possess 2n = 54 chromosomes and are either sex-homomorphic or sex-heteromorphic (regarding its chromosomes). We evaluated data on color, tooth morphology, cytogene
Genet. Mol. Biol.. Publicado em: 27/06/2019
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20. Comparative cytogenetics of nine populations of the Rhinella genus (Anura, Bufonidae) with a highlight on their conservative karyotype
Abstract The genus Rhinella is one of the most diverse groups of bufonid toads, currently composed by 93 valid species and naturally distributed throughout different Neotropical ecoregions. Here, we analyze nine Brazilian populations of toads representing species of the Rhinella margaritifera and Rhinella marina groups. These new data include the first descr
Genet. Mol. Biol.. Publicado em: 27/06/2019
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21. In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents
BACKGROUND Only benznidazole (Bnz) (1) and nifurtimox (Nfx) (2) are licensed for the treatment of Chagas disease although their safety and efficacy profile are far from ideal. Farmanguinhos from Fiocruz has developed seven nitroimidazole compounds (4-10) analogs of megazol (3). OBJECTIVES To evaluate whether the genotoxic effect of 3 was abolished in the
Mem. Inst. Oswaldo Cruz. Publicado em: 27/06/2019
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22. Persistent Mullerian duct Syndrome in a Brazilian miniature schnauzer dog
Abstract: Here we describe an eight-year-old miniature schnauzer (MS) dog from Brazil with Persistent Mullerian Duct Syndrome (PMDS) and the single base pair substitution in AMHR2 exon 3, first detected in this breed in the USA. This finding is evidence of mutation dissemination to South America. In PMDS, a type of XY Disorder of Sex Development (DSD), dogs
An. Acad. Bras. Ciênc.. Publicado em: 19/06/2019
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23. Management of chronic myeloid leukemia during pregnancy: a retrospective analysis at a single center
ABSTRACT We analyzed the management and outcomes of pregnancies of patients with chronic myeloid leukemia at a single center over fifteen years. Among the 203 CML female patients, there were ten pregnancies in seven women, all of them not planned. In three cases, the chronic myeloid leukemia diagnosis was made during pregnancy. Five patients received tyrosin
Hematol., Transfus. Cell Ther.. Publicado em: 10/06/2019
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24. Cytogenetic characterization of Angelonia integerrima Sprengel, a native species with ornamental potential
Abstract Angelonia integerrima Sprengel is a native species of the state of Mato Grosso do Sul and the Southern region (Paraná, Santa Catarina and Rio Grande do Sul) of Brazil, with features such as an unusual appearance and color of the flowers, indicating an ornamental use. To optimize the use of this species and to fill in gaps regarding its cytogenetic
Crop Breed. Appl. Biotechnol.. Publicado em: 11/04/2019