Cyclic Peptide
Mostrando 1-12 de 378 artigos, teses e dissertações.
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1. Evaluation of nasal mucociliary clearance by saccharine test in rheumatoid arthritis
Abstract Objective: We aimed to reveal whether there is nasal involvement by examining the Nasal Mucociliary Clearance (NMC) and the relationship between this activity and disease severity in Rheumatoid Arthritis (RA) patients. Methods: In this prospective study, NMC time, disease activity (Disease Activity Score 28) and blood parameters of RA patients (n
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Evaluation of monocyte to HDL cholesterol ratio and other inflammatory markers in patients with psoriasis,
Abstract Background Psoriasis is a chronic systemic inflammatory disease frequently associated with serious comorbidities. Objectives To investigate the systemic inflammatory burden in psoriasis and to assess the correlation between traditional and novel inflammatory markers and the severity of the disease. Methods This cross-sectional study was conducted
An. Bras. Dermatol.. Publicado em: 2020-10
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3. Linear Peptide Analogues from Jatropha’s Orbitides Promote Migration of Human Neonatal Foreskin Fibroblasts in vitro and Collagen Deposition
Orbitides are a class of small naturally occurring cyclic peptides with structural and functional diversities. Their chemical properties make this class feasible to be obtained by solid phase peptide synthesis (SPPS). Therefore, this synthetic accessibility enables useful application and facilitates the identification of analogues, bioactivity studies, and t
J. Braz. Chem. Soc.. Publicado em: 21/10/2019
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4. Acute exercise inhibits gastric emptying of liquids in rats: influence of the NO-cGMP pathway
We previously found that acute exercise inhibited the gastric emptying of liquid in awake rats by causing an acid-base imbalance. In the present study, we investigated the involvement of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway, vasoactive intestinal peptide (VIP), and corticotropin-releasing factor (CRF) peptide in this phenomenon.
Braz J Med Biol Res. Publicado em: 04/10/2018
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5. LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats
Inflammation plays a pivotal role in ischemic stroke, when activated microglia release excessive pro-inflammatory mediators. The inhibition of integrin αvβ3 improves outcomes in rat focal cerebral ischemia models. However, the mechanisms by which microglia are neuroprotective remain unclear. This study evaluated whether post-ischemic treatment with another
Braz J Med Biol Res. Publicado em: 01/08/2016
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6. Improvement of erectile dysfunction by the active pepide from Urechis unicinctus by high temperature/pressure and ultra - wave assisted lysis in Streptozotocin Induced Diabetic Rats
ABSTRACT Introduction: We investigate the effect of active peptide from Urechis unicinctus (UU) by high temperature/pressure and ultra-wave assisted lysis on erectile dysfunction in streptozotocin-induced diabetic rats. Materials and Methods: Forty 12-week-old Sprague-Dawley rats were used in this study. Diabetes was induced by a one-time intraperitoneal i
Int. braz j urol.. Publicado em: 2016-08
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7. Ixorine, a New Cyclopeptide Alkaloid from the Branches of Ixora brevifolia
The isolation and structure determination of new cyclic peptide alkaloid ixorine, along with five known constituents frangulanine, syringaresinol, cinnamtannin B-1, daucosterol and mannitol from the branches of Ixora brevifolia are described. The cyclic peptide frangulanine is being described for the first time in the Rubiaceae family. The structures were el
J. Braz. Chem. Soc.. Publicado em: 2016-04
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8. Determinação voltamétrica de ricina em mamona usando carbono vítreo e diamante dopado com boro / Voltammetric determination of ricin in castor bean using gassy carbon and boron doped diamond.
Ricin (RCA 60) is an inhibitor of ribosomes protein toxic, of class II, extracted from castor bean endosperm of the seed, consisting of two peptide chains (RCA-A 30 and RCA-B 30) linked by a disulfide bridge covalently formed by the combination of 17 amino acid residues. Its toxicity has been observed in animals, insects and humans, being by inhalation, inge
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/03/2012
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9. Síntese e caracterização de nanoestruturas peptídicas: estudos espectroscópicos e aplicações / Synthesis and characterization of peptide nanostructures: spectroscopic studies and applications
The study had as aimed the development of nanostructured materials based on processes of molecular self-assembly of peptide compounds in order to obtain systems of great structural versatility seeking possible applications related to bionanotechnology. In this regard, peptide sequences based on linear and cyclic precursors were synthesized by solid-phase met
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012
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10. Evaluation and biochemical characterization of a distinctive pyoverdin from a pseudomonas isolated from chickpea rhizosphere
Microbial siderophores confiscate the available ferric ions around the roots and trigger a reaction resulting in plant growth promotion. In our study, a high level of siderophore production was observed from a newly isolated Pseudomonas sp. from the rhizosphere of Chickpea plants. Under an iron depleted condition in Standard Succinic acid medium a 1000 µgmL
Brazilian Journal of Microbiology. Publicado em: 2012-06
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11. Wrist ultrasound analysis of patients with early rheumatoid arthritis
In the present study, we evaluated 42 wrists using the semi-quantitative scales power Doppler ultrasound (PDUS) and gray scale ultrasound (GSUS) with scores ranging from 0 to 3 and correlated the results with clinical, laboratory and radiographic data. Twenty-one patients (17 women and 4 men) with rheumatoid arthritis according to criteria of the American Co
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-01
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12. Association analysis of anti-Epstein-Barr nuclear antigen-1 antibodies, anti-cyclic citrullinated peptide antibodies, the shared epitope and smoking status in Brazilian patients with rheumatoid arthritis
INTRODUCTION: Epstein-Barr virus exposure appears to be an environmental trigger for rheumatoid arthritis that interacts with other risk factors. Relationships among anti-cyclic citrullinated peptide antibodies, the shared epitope, and smoking status have been observed in patients with rheumatoid arthritis from different populations. OBJECTIVE: To perform an
Clinics. Publicado em: 2011