Cutaneous Irritation
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine creams (3-PACK) on Leishmania (Viannia) braziliensis-infected mice
BACKGROUND Topical treatment of New World cutaneous leishmaniasis can be affected by bacterial coinfection, hyperkeratosis, and transdermal drug delivery. OBJECTIVE The aim of this work was to evaluate the therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine isethionate (PMD) creams (3-PACK kit) on CL
Mem. Inst. Oswaldo Cruz. Publicado em: 13/05/2019
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2. Atypical presentation of fibroepithelial polyp: a report of two cases
RESUMO Pólipos fibroepiteliais são tumores benignos não-epiteliais que surgem do tecido mesodérmico e são comumente encontrados na pele. Eles podem se desenvolver na pálpebra e na área adjacente, e raramente aparecem em outros locais. Embora a maioria dos casos cutâneos seja diagnosticada incidentalmente, as lesões podem ser sintomáticas com base e
Arq. Bras. Oftalmol.. Publicado em: 25/03/2019
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3. Promotion of cutaneous penetration of nifedipine for nanoemulsion
ABSTRACT This article reports the development and characterization of a nanoemulsion (NE) able to improve the cutaneous penetration of nifedipine. NE with nifedipine was development and characterized, presenting droplet size of 20 nm with low polydispersity index (IP<0.1), spherical shape without aggregation, pH compatible with typical skin levels and stabil
Braz. J. Pharm. Sci.. Publicado em: 06/07/2017
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4. Desenvolvimento e avaliação clínica dos efeitos de formulações dermocosméticas contendo dimetilaminoetanol ou acetil hexapeptídeo-3 / Development and clinical evaluation of the effects of dermocosmetic formulations containing dimethylaminoetanol or acetyl hexapeptide-3.
Dimethylaminoethanol (DMAE) and acetyl hexapeptide-3 (AHP) have been used in dermocosmetic formulations for anti-aging purposes. However, few scientific papers are concerned about the effects of these active substances on cutaneous tissue. Thus, the aim of the present study is the development, evaluation of physical stability, safety and clinical efficacy of
Publicado em: 2009
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5. Avaliação físico-química e tecnológica da fração saponosídica dos frutos de ilex paraguariensis A. St. Hil. : potencialidade como adjuvante espumógeno / Physico-Chemical and Technologycal avaliation of the saponins of Ilex paraguariensis A. St. Hil. fruits : potential adjuvant foaming
As saponinas são tensoativos naturais, caracterizadas principalmente por sua atividade espumógena. Ilex paraguariensis A. St. Hil, conhecida como “erva-mate”, é uma espécie vegetal rica em saponinas e de importância econômica e cultural para este Estado. Estudos anteriores demonstraram que os frutos imaturos de I. paraguariensis, uma parte do veget
Publicado em: 2007
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6. In vitro citotoxicity test as an alternative to in vivo Draize test for the evaluation of cosmetic / Teste de citotoxicidade in vitrocomo alternativa ao teste in vivode Draize na avaliação de produtos cosméticos
The procedures described by Draize are the basis of both ocular and cutaneous irritation tests and have been adopted internationally for in vivo evaluation of products and substances. However, they have been criticized for ethical reasons, due to their cruelty towards animals. Therefore, alternative methodologies are being studied to evaluate the toxicity of
Publicado em: 2003
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7. The Novel Immunosuppressive Agent Mycophenolate Mofetil Markedly Potentiates the Antiherpesvirus Activities of Acyclovir, Ganciclovir, and Penciclovir In Vitro and In Vivo
The immunosuppressive agent mycophenolate mofetil (MMF) has been approved for use in kidney transplant recipients and may thus be used concomitantly for the treatment of intercurrent herpesvirus infections with drugs such as acyclovir (ACV), ganciclovir (GCV), and penciclovir (PCV). We found that MMF and its parent compound mycophenolic acid (at concentratio
American Society for Microbiology.