Crude Venom
Mostrando 13-24 de 78 artigos, teses e dissertações.
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13. Identification of two novel cytolysins from the hydrozoan Olindias sambaquiensis (Cnidaria)
Background : Although the hydrozoan Olindias sambaquiensis is the most common jellyfish associated with human envenomation in southeastern and southern Brazil, information about the composition of its venom is rare. Thus, the present study aimed to analyze pharmacological aspects of O. sambaquiensis venom as well as clinical manifestations observed in affec
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 25/03/2014
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14. Hemolytic activity of venom from crown-of-thorns starfish Acanthaster planci spines
Background : The crown-of-thorns starfish Acanthaster planci is a venomous species from Taiwan whose venom provokes strong hemolytic activity. To understand the hemolytic properties of A. planci venom, samples were collected from A. planci spines in the Penghu Islands, dialyzed with distilled water, and lyophilized into A. planci spine venom (ASV) powder. R
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 25/09/2013
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15. Resistance of cervical adenocarcinoma cells (HeLa) to venom from the scorpion Centruroides limpidus limpidus
Background : The venom of Centruroides limpidus limpidus (Cll) is a mixture of pharmacologically active principles. The most important of these are toxic proteins that interact both selectively and specifically with different cellular targets such as ion channels. Recently, anticancer properties of the venom from other scorpion species have been described.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/09/2013
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16. Toxins from the Caribbean sea anemone Bunodeopsis globulifera increase cisplatin-induced cytotoxicity of lung adenocarcinoma cells
Background Lung cancer causes 1.4 million deaths worldwide while non-small-cell lung cancer (NSCLC) represents 80-85% of the cases. Cisplatin is a standard chemotherapy against this type of cancer; however, tumor cell resistance to this drug limits its efficacy. Sea anemones produce compounds with pharmacological activities that may be useful for augmenting
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 07/05/2013
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17. Effects of the European hornet ( Vespa crabro Linnaeus 1761) crude venom on its own species
Background Lethal dose 50% is a classical index of toxicity that usually employs small rodents as experimental animals. Therefore, scarce data are available on the effects of venom on invertebrates, particularly the impact of wasp venom on its own species. Findings In the present study, the lethality of Vespa crabro venom on its own species was studied. Let
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/03/2013
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18. In vivo evaluation of homeostatic effects of Echis carinatus snake venom in Iran
Background The venom of the family Viperidae, including the saw-scaled viper, is rich in serine proteinases and metalloproteinases, which affect the nervous system, complementary system, blood coagulation, platelet aggregation and blood pressure. One of the most prominent effects of the snake venom of Echis carinatus (Ec) is its coagulation activity, used f
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/02/2013
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19. Inhibitory effect of a Brazilian marine brown alga Spatoglossum schröederi on biological activities of Lachesis muta snake venom
The ability of crude extracts of the brown seaweed Spatoglossum schröederi to counteract some of the biological activities of Lachesis muta snake venom was evaluated. In vitro assays showed that only the extract of S. schröederi prepared in ethyl acetate was able to inhibit the clotting of fibrinogen induced by L. muta venom. On the other hand, all extract
Revista Brasileira de Farmacognosia. Publicado em: 17/04/2012
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20. Embryotoxicity following repetitive maternal exposure to scorpion venom
Although it is a frequent accident in a few countries, scorpion envenomation during pregnancy remains scarcely studied. In the present study, the effects of repetitive maternal exposure to Buthus occitanus tunetanus venom are investigated and its possible embryotoxic consequences on rats. Primigravid rats received a daily intraperitoneal dose of 1 mL/kg of s
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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21. Antibacterial properties of contact defensive secretions in neotropical Crematogaster ants
Crematogaster ants use their contact venoms to compete with other ants. Although those venoms are used primarily as repellent and toxic secretions, they may have other functions. The present study aimed to test the antibacterial property of abdominal venom of three neotropical Crematogaster ant species (C. distans, C. pygmaea and C. rochai) against gram-nega
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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22. Characterization of the allergen Sol gem 2 from the fire ant venom, Solenopsis geminata
Sol i 2 is a potent allergen in Solenopsis invicta venom, and most humans exhibit reactivity to it. The Sol gem 2 allergen found in the venom of the Thai tropical fire ant Solenopsis geminata was analysed in the present study. The protein was present in higher amounts than other proteins, as determined by SDS-PAGE, and presumably has allergenic properties si
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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23. Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom
Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus. Recent studies show that atheromatous plaque is prone to thrombosis due to endothelial cell apoptosis. To the best of our knowle
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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24. Pharmacological and partial biochemical characterization of Bmaj-9 isolated from Bothrops marajoensis snake venom
Bmaj-9, a basic PLA2 (13679.33 Da), was isolated from Bothrops marajoensis snake venom through only one chromatographic step in reversed phase HPLC on ¼-Bondapak C-18 column. The amino acid composition showed that Bmaj-9 had a high content of Lys, His, and Arg, typical of a basic PLA2. The sequence of Bmaj-9 contains 124 amino acid residues with a pI value
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012