Coronary Blood Flow And Adenosine
Mostrando 1-12 de 28 artigos, teses e dissertações.
-
1. Effects of simvastatin/ezetimibe on microparticles, endothelial progenitor cells and platelet aggregation in subjects with coronary heart disease under antiplatelet therapy
It is not known whether the addition of ezetimibe to statins adds cardiovascular protection beyond the expected changes in lipid levels. Subjects with coronary heart disease were treated with four consecutive 1-week courses of therapy (T) and evaluations. The courses were: T1, 100 mg aspirin alone; T2, 100 mg aspirin and 40 mg simvastatin/10 mg ezetimibe; T3
Braz J Med Biol Res. Publicado em: 15/04/2014
-
2. Moderate exercise training promotes adaptations in coronary blood flow and adenosine production in normotensive rats
OBJECTIVES: Aerobic exercise training prevents cardiovascular risks. Regular exercise promotes functional and structural adaptations that are associated with several cardiovascular benefits. The aim of this study is to investigate the effects of swimming training on coronary blood flow, adenosine production and cardiac capillaries in normotensive rats. METHO
Clinics. Publicado em: 2011
-
3. Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
OBJECTIVES: We evaluated the impairment of endothelium-dependent and endothelium-independent coronary blood flow reserve after administration of intracoronary acetylcholine and adenosine, and its association with hypertensive cardiac disease. INTRODUCTION: Coronary blood flow reserve reduction has been proposed as a mechanism for the progression of compensat
Clinics. Publicado em: 2009-04
-
4. Efeitos do uso de esteróides anabolizantes associados ao treinamento físico de natação sobre o fluxo sangüíneo para o miocárdio de ratos normotensos / Effects of anabolic steroids use associated with swimming exercise training on myocardium blood flow of normotensive rats
The abusive use of ergogenic resources as the anabolic steroid became an increasing problem in several segments of the population, beyond the athletical way, searching for better performance or physical appearance, without being worried about the risks of the collateral effects promoted by this practice. In the present work we studied the effects of the use
Publicado em: 2007
-
5. Study of Coronary Sinus Flow Reserve Through Transesophageal Doppler Echocardiography in Normal Subjects
OBJECTIVE - To evaluate the Coronary Flow Reserve in the Coronary Sinus through transesophageal Doppler echocardiography in normal subjects. METHODS - We obtained technically adequate flow samples for analysis in 10 healthy volunteers (37±8 years, 5 men) with no history of heart or systemic disease and with mean left ventricular mass index by transthoracic
Arquivos Brasileiros de Cardiologia. Publicado em: 2002-08
-
6. Efeito da cafeina na função cardiaca de ratos treinados
The effect of caffeine on the cardiovascular system has been largely investigated. However, conflictant results have been found, some investigators showed that caffeine increases blood pressure after caffeine increases blood pressure after caffeine treatment. Therefore, the aim of this work was to investigate the effect of caffeine treatment on the cardiac p
Publicado em: 2001
-
7. Coronary flow reserve in patients with chest pain and normal coronary arteries.
BACKGROUND--Many studies have shown that coronary flow reserve is reduced in patients with chest pain and angiographically normal coronary arteries. The methods used to assess coronary blood flow have varied, but in nearly all reports dipyridamole has been used to bring about vasodilatation. This study was designed to assess whether the apparent impairment o
-
8. Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs.
The activation of platelets and the formation of neutrophil- platelet conjugates may lead to the development of thromboemboli. We studied whether blockade of adenosine receptors during coronary hypoperfusion may cause thromboemboli via P-selectin-dependent mechanisms in 30 open-chest dogs. When coronary blood flow was reduced to 20% of the control, it was st
-
9. Role of K+ ATP channels and adenosine in the regulation of coronary blood flow during exercise with normal and restricted coronary blood flow.
Regulation of coronary vasomotor tone during exercise is incompletely understood. We investigated the contributions of K+ ATP channels and adenosine to the coronary vasodilation that occurs during exercise in the normal heart and in the presence of a coronary artery stenosis. Dogs that were chronically instrumented with a Doppler flow probe, hydraulic occlud
-
10. Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
The mechanism of coronary vasodilation produced by exercise is not understood completely. Recently, we reported that blockade of vascular smooth muscle K(ATP)+ channels decreased coronary blood flow at rest, but did not attenuate the increments in coronary flow produced by exercise. Adenosine is not mandatory for maintaining basal coronary flow, or the incre
-
11. Coronary haemodynamics in left ventricular hypertrophy.
BACKGROUND: Left ventricular hypertrophy is associated with an increased risk of cardiovascular morbidity and mortality. Previous studies have shown that patients with left ventricular hypertrophy develop electrocardiographic changes and left ventricular dysfunction during acute hypotension, and suggest that the lower end of autoregulation may be shifted upw
-
12. The role of adenosine in functional hyperaemia in the coronary circulation of anaesthetized dogs.
1. The aim of this investigation was to determine the contribution of adenosine to coronary active hyperaemia in the dog denervated heart by using adenosine deaminase. 2. Beagles were anaesthetized with thiopentone sodium (500 mg, I.V.) and chloralose (100 mg kg-1, LV.) and artificially ventilated. The hearts were denervate by bilateral cervical vagotomy and