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Mostrando 1-12 de 6188 artigos, teses e dissertações.
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1. The complete chloroplast genome sequence of Vincetoxicum mongolicum (Apocynaceae), a perennial medicinal herb
Abstract Vincetoxicum mongolicum Maxim. (1876), is a perennial medicinal herb, widely distributed in the Loess Plateau of China. Here, we sequenced, assembled, and annotated the complete chloroplast (cp) genome of V. mongolicum, and compared the highly variable gene regions and phylogenetic positions between V. mongolicum and other related species. Results s
Genetics and Molecular Biology. Publicado em: 2023
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2. Quantification of cell-free circulating mitochondrial DNA copy number variation in hepatocellular carcinoma
SUMMARY OBJECTIVE: Hepatocellular carcinoma is the most common primary malignant liver tumor. Mitochondrial DNA copy number has been shown to be associated with various malignancies. However, there has not been any study on the absolute quantification of mtDNA copy number in hepatocellular carcinoma. The aim of this study was to develop a new method for abs
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. T3 therapy for hypothyroidism: choosing wisely still requires careful bench to bedside translation
ABSTRACT Objective: To study the association of SLC16A11 gene variants with obesity and metabolic markers in nondiabetic Chilean adults. Materials and methods: This cross-sectional study included 263 non-diabetic adults. The genotype of the rs75493593 polymorphism of SLC16A11 gene was performed by real-time PCR. It's association with adiposity markers (bod
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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4. Genetic variants in the SLC16A11 gene are associated with increased BMI and insulin levels in nondiabetic Chilean population
ABSTRACT Objective: To study the association of SLC16A11 gene variants with obesity and metabolic markers in nondiabetic Chilean adults. Materials and methods: This cross-sectional study included 263 non-diabetic adults. The genotype of the rs75493593 polymorphism of SLC16A11 gene was performed by real-time PCR. It's association with adiposity markers (bod
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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5. Targeted massively parallel sequencing for congenital generalized lipodystrophy
ABSTRACT Objective: Our aim is to establish genetic diagnosis of congenital generalized lipodystrophy (CGL) using targeted massively parallel sequencing (MPS), also known as next-generation sequencing (NGS). Subjects and methods: Nine unrelated individuals with a clinical diagnosis of CGL were recruited. We used a customized panel to capture genes related
Arch. Endocrinol. Metab.. Publicado em: 2020-10
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6. Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay,
Abstract Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis. Accumulating evidence indicates that oxidative stress can induce mitochondrial DNA (mtDNA) damage and variations in mtDNA copy number (mtDNAcn). Objective: The aim of this study was to exp
An. Bras. Dermatol.. Publicado em: 2020-06
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7. Transcription factors and molecular markers revealed asymmetric contributions between allotetraploid Upland cotton and its two diploid ancestors
ABSTRACT Three Gossypium species have been used to breed cotton as they vary in their fiber production and resistance to stresses. Transcription factors (TFs) mostly are present in different copies or isoforms by which they conduct their regulation. Their copy number can determine organism behavior to a cue. Simple sequence repeats (SSRs) are one of the most
Bragantia. Publicado em: 2020-03
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8. Araucaria angustifolia chloroplast genome sequence and its relation to other Araucariaceae
Abstract Araucaria angustifolia is endemic to southern Brazil. Known as Brazilian pine, A. angustifolia is the only native conifer species with economic and social relevance in this country. Due to massive exploitation, it has suffered a significant population decline and currently is classified as critically endangered. This encouraged the scientific commun
Genet. Mol. Biol.. Publicado em: 14/11/2019
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9. Evaluation of OFDM Channel Sounding Techniques with Three Modulation Sequences
Abstract This paper presents an evaluation of multicarrier channel sounding techniques using different random and pseudo-random sequences to modulate the OFDM sounding signal. The Random (Rand), Pseudo-Noise (PN) and Zadoff-Chu (ZC) were tested, both in laboratory simulations and in field measurements. For the laboratory simulations Matlab routines were used
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 11/11/2019
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10. Target Search for Transcription Factors on DNA Chains
RESUMO Entre muitas estruturas presentes nas células dos seres vivos, existem proteínas chamadas fatores de transcrição (FT) que são responsáveis por inibir ou promover a transcrição do ADN. Para realizar sua função, os fatores de transcrição executam buscas aleatórias ao redor do citoplasma (para células procarióticas) e ao longo da cadeia de
TEMA (São Carlos). Publicado em: 16/09/2019
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11. INVESTIGATION OF ENTEROCOCCUS FAECALIS POPULATION IN PATIENTS WITH POLYP AND COLORECTAL CANCER IN COMPARISON OF HEALTHY INDIVIDUALS
RESUMO CONTEXTO: O câncer colorretal é um dos cânceres mais comumente diagnosticados em todo o mundo. Um dos fatores envolvidos no desenvolvimento do câncer colorretal é a mudança na flora normal do intestino. OBJETIVO: O número médio de cópias de Enterococcus faecalis em pessoas com pólipos e pessoas com câncer colorretal foram avaliados em c
Arq. Gastroenterol.. Publicado em: 26/08/2019
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12. Genetic drift in mammals
Abstract: Genetic drift is the fortuitous occurrence of genetic events that when they become fixed modify the genome of populations. They can take the form of mutations of single nucleotides (SNPs), the insertion or deletion of short sequences (Indels) or the repetitions of short sequences (CNV i.e. copy number variants) or long insertions or deletion (struc
An. Acad. Bras. Ciênc.. Publicado em: 26/08/2019