Conditioned Fear
Mostrando 1-12 de 57 artigos, teses e dissertações.
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1. Critical neuropsychobiological analysis of panic attack- and anticipatory anxiety-like behaviors in rodents confronted with snakes in polygonal arenas and complex labyrinths: a comparison to the elevated plus- and T-maze behavioral tests
Objective: To compare prey and snake paradigms performed in complex environments to the elevated plus-maze (EPM) and T-maze (ETM) tests for the study of panic attack- and anticipatory anxiety-like behaviors in rodents. Methods: PubMed was reviewed in search of articles focusing on the plus maze test, EPM, and ETM, as well as on defensive behaviors displaye
Rev. Bras. Psiquiatr.. Publicado em: 06/02/2017
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2. Animal models of anxiety disorders and stress
Anxiety and stress-related disorders are severe psychiatric conditions that affect performance in daily tasks and represent a high cost to public health. The initial observation of Charles Darwin that animals and human beings share similar characteristics in the expression of emotion raise the possibility of studying the mechanisms of psychiatric disorders i
Rev. Bras. Psiquiatr.. Publicado em: 2013
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3. Envolvimento de mecanismos glutamatérgicos da substância cinzenta periaquedutal dorsal e do hipotálamo medial no medo condicionado à luz / Involvement of glutamatergic mechanisms of the dorsal periaqueductal gray matter and medial hypothalamus in conditioned fear to the light
A substância cinzenta periaquedutal dorsal (dPAG) e o hipotálamo medial (MH) são duas estruturas encefálicas que estão envolvidas na elaboração de estados aversivos e expressão de respostas defensivas. A estimulação elétrica da dPAG ou do MH produz uma série de respostas comportamentais que se assemelham às respostas defensivas induzidas pela pr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/09/2012
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4. Envolvimento de mecanismos dopaminérgicos na expressão do medo condicionado contextual em ratos / Involvement of dopaminergic mechanisms in the expression of contextual conditioned fear in rats
É reconhecido que as experiências que geram reações de medo são praticamente indeléveis do encéfalo dos organismos e que condicionamentos aversivos suscitam inúmeras respostas defensivas, como o congelamento, sendo esta resposta um indicador de medo em roedores. Vários trabalhos têm apontado para a relação entre alterações na transmissão dopam
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/04/2012
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5. ROLE OF DORSAL AND VENTRAL HIPPOCAMPUS ON CONDITIONED AND UNCONDITIONED FEAR ELICITED BY DORSAL PERIAQUEDUCTAL GREY MATTER ELECTRICAL STIMULATION IN RATS / PARTICIPAÇÃO DO HIPOCAMPO DORSAL E VENTRAL NAS REAÇÕES DE DEFESA PRODUZIDAS PELO CONDICIONAMENTO CONTEXTUAL DE MEDO E PELA ESTIMULAÇÃO ELÉTRICA DA MATÉRIA CINZENTA PERIAQUEDUTAL DORSAL
This study investigates the role of the hippocampus in both unconditioned and conditioned defense behavior by examining the effects of pre-training electrolytic lesions to the dorsal and ventral hippocampus in male rats exposed to two types of threat stimuli: electrical stimulation of the DPAG and footshock. Our results indicate that ventral and dorsal lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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6. Gabaergic mechanisms of anterior and ventromedial hypothalamic nuclei in the expression of freezing in response to a light-conditioned stimulus
The amygdala, dorsal periaqueductal gray (dPAG), and medial hypothalamus have long been recognized to comprise a neural system responsible for the generation and elaboration of unconditioned fear in the brain. This neural substrate is well known to be under tonic inhibitory control exerted by γ-aminobutyric acid (GABA) mechanisms. Some evidence also suggest
Psychology & Neuroscience. Publicado em: 2011
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7. Panic-like behaviors in Carioca High-and Low-conditioned Freezing rats
Panic disorder involves both recurrent unexpected panic attacks and persistent concern about having additional attacks. Electrical stimulation of the dorsal periaqueductal gray (dPAG) is an animal model of both panic attack and panic disorder, whereas contextual fear conditioning represents a model of anticipatory anxiety. Previous research indicated that an
Psychology & Neuroscience. Publicado em: 2011
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8. Effects of reversible inactivation of the dorsomedial hypothalamus on panic- and anxiety-related responses in rats
The medial hypothalamus is part of a neurobiological substrate controlling defensive behavior. It has been shown that a hypothalamic nucleus, the dorsomedial hypothalamus (DMH), is involved in the regulation of escape, a defensive behavior related to panic attacks. The role played by the DMH in the organization of conditioned fear responses, however, is less
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-09
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9. Effects of contextual fear conditioning and pentylenetetrazol on panic-like reactions induced by dorsal periaqueductal gray stimulation with N-methyl-D-aspartate
Electrical or chemical stimulation of the dorsal periaqueductal gray (DPAG) has been accepted as an animal model of panic attacks. This study investigates the influence of anticipatory anxiety in the occurrence of panic-like behavior induced by N-methyl-D-aspartate (NMDA) microinjection into the DPAG of rats. Behavioral (i.e., contextual fear conditioning) a
Psychology & Neuroscience. Publicado em: 2010-06
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10. Involvement of dopaminergic receptors of ventral tegmental area and basolateral amygdala in the acquisition and expression of conditioned fear / Envolvimento de receptores dopaminérgicos da área tegmental ventral e do complexo basolateral da amígdala na aquisição e na expressão do medo condicionado
OLIVEIRA, A.R. Envolvimento de receptores dopaminérgicos da área tegmental ventral e do complexo basolateral da amígdala na aquisição e na expressão do medo condicionado. 2010. 93 f. Tese (Doutorado) Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo. O condicionamento Pavloviano é um dos paradigmas mais utilizad
Publicado em: 2010
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11. Strain and sex differences in fear conditioning: 22 kHz ultrasonic vocalizations and freezing in rats
Strain and sex differences in fear conditioning were investigated in two commonly used laboratory rats: Sprague Dawleys and Long-Evans. Twenty-two kHz ultrasonic vocalization (USV) distress calls and freezing behavior were used to measure fear responses to contextual and auditory conditioned stimuli (CSs), which were previously paired with a footshock uncond
Psychology & Neuroscience. Publicado em: 2009-12
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12. POLIAMINERGIC AGENTS MODULATE CONTEXTUAL FEAR EXTINCTION IN RATS / AGENTES POLIAMINÉRGICOS MODULAM A EXTINÇÃO DO MEDO CONDICIONADO CONTEXTUAL EM RATOS
Polyamines, such as spermidine and spermine, have been reported to improve memory retention through the activation of N-methyl-D-aspartate receptors (NMDAr). However whether polyamine agonists and antagonists alter extinction remains unclear. In the current study, we investigated whether spermidine and polyamine antagonists that selectively block the NR2B su
Publicado em: 2009