Colonic Neoplasms
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Streptococcus gallolyticus Bacteremia Detected in Apheresis Platelets and Its Link to Colonic Neoplasms
Abstract Introduction Streptococcus gallolyticus belongs to theStreptococcus bovis complex, and it is a common bacterium colonizing the gastrointestinal tract. Its presence in the blood may suggest an underlying pathology such as a colonic neoplasm. We report herein a case of S. bovis bacteremia in an apheresis platelet donor, review similar cases in the li
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2022
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2. Influence of genetic polymorphisms in metabolism of folic acid in susceptibility to sporadic colorectal adenocarcinoma / Influência de polimorfismos gênicos do metabolismo do ácido fólico na susceptibilidade ao adenocarcinoma colorretal esporádico = : Influence of genetic polymorphisms in metabolism of folic acid in susceptibility to sporadic colorectal adenocarcinoma
O desenvolvimento de câncer colorretal (CCR) é resultado de uma complexa interação de variáveis, incluindo elementos externos, como a exposição a agentes ambientais e dietéticos, e fatores internos, de natureza somática ou hereditária. Não está estabelecido se genótipos de polimorfismos de baixa penetrância em genes relacionados com o metabolis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2012
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3. Immunohisthochemical expression of ErbB family receptors and their prognostic role in patients with colorectal cancer with high risk of recurrence after radical surgery / Perfil da expressão imunoistoquímica dos receptores da família ErbB e seu prognóstico em pacientes com câncer de cólon e reto com alto risco para recorrência após cirurgia radical
INTRODUÇÃO: Deve-se considerar que cerca de 70 a 80% dos pacientes portadores de carcinoma colorretal estádio II podem ser curados apenas com cirurgia. Por outro lado, a despeito do tratamento empregado e dos benefícios alcançados com a evolução dos tratamentos adjuvantes, cerca de 20 a 35% dos pacientes tratados com doença em estádio III vêm a fal
Publicado em: 2008
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4. Irinotecano ativa a via PI3-quinase/AKT/mTOR em linhagem de adenocarcinoma de colon / Chronic treatment with irinotecan activates the PI3K/AKT/mTOR pathway in HT-29 colon cancer xenografts
Resistance of tumors to chemotherapeutic agents is a common clinical problem in human cancer. Recently, the blocking of PI3-kinase signaling pathway was shown to enhance apoptosis induced by SN-38, an active form of irinotecan. To gain further insight into the molecular events of irinotecan-associated increase in PI3-kinase signaling pathway, aspirin and rap
Publicado em: 2007
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5. Papilomavirus humano (HPV) e co-fatores de risco em mulheres submetidas a rastreamento para câncer de cérvice uterina. Unidade Materno Infantil do Marco. Belém, Pará, Brasil / Human papillomavirus (HPV) and co factores of risk in womens submitted the tracking to cancer of cervix uteri. Maternal child unit of Marco. Belem, Para, Brazil.
O Papilomavirus humano (HPV) é reconhecido como o agente causal do câncer de colo uterino, patologia que representa a segunda maior causa de óbito por câncer em mulheres no mundo, ocupando o primeiro lugar entre aquelas de 35 a 45 anos em vários países em desenvolvimento. Acredita-se, entretanto, que outros fatores contribuam para a evolução maligna
Publicado em: 2007
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6. High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
Polyamines are required for cell proliferation, and ornithine decarboxylase (ODC) is the first and probably rate-limiting enzyme in their synthesis. Tissue containing colonic or rectal adenocarcinomas (N = 34) or polyps (N = 6) and noninvolved paired colonic mucosa were obtained from fresh surgical specimens. ODC activity was elevated (mean: 320%) in both th
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7. Proliferation rate of colonic mucosa in normal subjects and patients with colonic neoplasms: a refined immunohistochemical method.
An increased colonic epithelial proliferation rate and an increase of the cryptal proliferative zone are probable markers of increased susceptibility to colonic cancer. In this study an immunohistochemical method using 5-bromo-deoxyuridine (BrdUrd) to measure the proliferation rate of colonic mucosa in vitro was used. Fresh endoscopic colonic biopsy specimen
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8. High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.
DNA methylation abnormalities occur consistently in human neoplasia including widespread hypomethylation and more recently recognized local increases in DNA methylation that hold potential for gene inactivation events. To study this imbalance further, we have cloned and localized to chromosome 19 a portion of the human DNA methyltransferase gene that codes f
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9. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin.
AIMS--To provide a detailed knowledge of the distribution of the CD13 molecule, also known as the protease aminopeptidase-N, on both normal tissues and malignant neoplasms of epithelial and lymphoid origin. METHODS--CD13 antigen was examined by immunocytochemistry, using a recently produced antibody (VS5E) alongside a commercially available anti-CD13 monoclo
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10. Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation.
Hereditary non-polyposis colorectal cancer (HNPCC) is characterised by a genetic predisposition to develop colorectal cancer at an early age and, to a lesser degree, cancer of the endometrium, ovaries, urinary tract, and organs of the gastrointestinal tract other than the colon. In the majority of families the disease is linked to mutations in one of the two
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11. The natural history of surgically treated primary adenocarcinoma of the appendix.
OBJECTIVE: The aim of this investigation was to determine the prognostic variables and optimal surgical procedure for patients with adenocarcinoma of the appendix. SUMMARY BACKGROUND DATA: Primary adenocarcinoma of the appendix is a rare malignancy that constitutes less than 0.5% of all gastrointestinal neoplasms. However, the prognostic factors and the pref
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12. Clusterin as a biomarker in murine and human intestinal neoplasia
Early detection of colorectal cancer is critical for the management of this disease. Biomarkers for early detection of several cancers have been developed and applied clinically in recent years. We have sought to discover candidate biomarkers without the restricted choice of markers placed on microarrays, and without the biological complications of genet
National Academy of Sciences.