Colloidal Silicon Dioxide
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Compatibility by a Nonisothermal Kinetic Study of Azathioprine Associated with Usual Excipients in the Product Quality Review Process
Azathioprine is an immunosuppressive drug for several inflammatory disorders. Due to its clinical relevance, to explore the solid-state properties for excipient compatibility in the product quality review process is essential. Fourier transform infrared spectroscopy, powder X-ray diffraction and thermal analysis (thermogravimetry/derivative thermogravimetry
J. Braz. Chem. Soc.. Publicado em: 2021-03
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2. Pharmaceutical development of tablets containing a spray-dried optimized extract from Lippia origanoides H. B. K.: influence of excipients and toxicological assessment
ABSTRACT Lippia origanoides is a honey shrub which has showed hypotensive potential assessed by in vivo studies. The aim of this work is the development of a pharmaceutical formulation composed by an optimized extract obtained from aerial parts of L. origanoides. The quantification of the naringenin marker in the dry extract and tablets developed was perform
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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3. Obtenção e caracterização do extrato seco Padronizado de Vernonanthura ferruginea (LESS.) H. Rob., Asteraceae (Assa-Peixe) / Obtaining and chacterization of santadardized dry extract of Vernonanthura ferruginea (LESS.) H. Rob., Asteraceae
Vernonanthura ferruginea (Less.) H. Rob. (Asteraceae), a typical plant of the Brazilian savannah, popularly known as assa-peixe, presented analgesic, antiedematogenic, antioxidant and antiulcer activities in scientific studies. But in literature there are no works related to the production of dried extracts of this plant species. In this work, standardized s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/04/2011
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4. Obtenção e caracterização do extrato seco Padronizado de Vernonanthura ferruginea (LESS.) H. Rob., Asteraceae (Assa-Peixe) / Obtaining and chacterization of santadardized dry extract of Vernonanthura ferruginea (LESS.) H. Rob., Asteraceae
Vernonanthura ferruginea (Less.) H. Rob. (Asteraceae), a typical plant of the Brazilian savannah, popularly known as assa-peixe, presented analgesic, antiedematogenic, antioxidant and antiulcer activities in scientific studies. But in literature there are no works related to the production of dried extracts of this plant species. In this work, standardized s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/04/2011
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5. Desenvolvimento tecnológico de forma farmacêutica plástica contendo extrato seco nebulizado de Achyrocline satureioides (Lam.) DC. Compositae (Marcela) / Technological devewpment of a plastic dosage form containing spray dried extracts from achyrocline satureioides( lam.) dc compositae
Extratos secos apresentam vantagens sobre fluidos e moles, como facilidade de manipulação e conservação. O presente trabalho consiste na incorporação de extratos secos nebulizados de Achyrocline satureioides, contendo combinações de dióxido de silício coloidal, celulose microcristalina e β-ciclodextrina como adjuvantes de nebulização, em base de
Publicado em: 2010
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6. Determinação de sibutramina em formas farmacêuticas através de espectroscopia no infravermelho com refletância difusa e métodos de calibração multivariada
The goal of this work is the development and validation of an analytical method for fast quantification of sibutramine in pharmaceutical formulations, using diffuse reflectance infrared spectroscopy and partial least square regression. The multivariate model was elaborated from 22 mixtures containing sibutramine and excipients (lactose, microcrystalline cell
Química Nova. Publicado em: 2010
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7. Parâmetros de produção e caracterização de produto seco de maytenus ilicifolia Martius ex Reissek - celastraceae - em torre de secagem por aspersão / Process parameters and characterization of Maytenus ilicifolia Martius ex Reissek – Celastraceae spray dried products
O presente trabalho teve como objetivo verificar a influência dos parâmetros tecnológicos do processo de secagem por aspersão sobre as características do produto obtido a partir de extrato seco de Maytenus ilicifolia. Para tanto, foi realizado um estudo exploratório, utilizado um desenho experimental fatorial, analisando quatro parâmetros: a concentra
Publicado em: 2009
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8. Produção de extratos secos padronizados de plantas medicinais brasileiras: estudo da viabilidade técnica e econômica do processo em leito de jorro / Standardized dried extracts of Brazilian medicinal plants: assessment of technical and economical feasibility of the spouted bed drying
The aim of this work was to investigate the technological and economical feasibility of the spouted bed drying process for production of the standardized dried extracts of Brazilian medicinal plants using the Bauhinia forficata Link as an experimental model. The objective was to demonstrate the potential of this technology for the processing of medicinal pla
Publicado em: 2007
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9. Preparation and characterization of Pluronic-colloidal silicon dioxide composite particles as liquid crystal precursor
The purpose of this study was to produce spray-dried Pluronic-colloidal silicon dioxide (Aerosil) composite particles as a liquid crystal precursor that would form a liquid crystalline phase upon hydration. A Pluronic-colloidal silicon dioxide dispersion in isopropyl alcohol was spray-dried to obtain composite particles using different concentrations of Aero
Springer-Verlag.
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10. Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities
The purpose of this study was to develop an instrument (the Purdue instrument) and the corresponding methodologies to measure the electrostatic charge development (chargeability) of dry powders when they are in dynamic contact with stainless steel surfaces. The system used an inductive noncontact sensor located inside an aluminum Faraday cage and was optimiz
Springer-Verlag.
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11. Observations on the Pathogenesis of Silicosis by Means of the Diffusion Chamber Technique
An attempt has been made to determine whether the diffusion chamber technique can be used to decide the validity of the silica solubility theory of the pathogenesis of silicosis. Small chambers were constructed from membranes of a pore size which allowed free passage of colloidal silicic acid and tissue fluids but which prevented the entry of host cells and
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12. Dry granulation and compression of spray-dried plant extracts
The purpose of this research was to evaluate the influence of dry granulation parameters on granule and tablet properties of spray-dried extract (SDE) fromMaytenus ilicifolia, which is widely used in Brazil in the treatment of gastric disorders. The compressional behavior of the SDE and granules of the SDE was characterized by Heckel plots. The tablet proper
Springer-Verlag.