Cns Activity
Mostrando 1-12 de 197 artigos, teses e dissertações.
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1. Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat
ABSTRACT Rabies encephalitis is a fatal zoonotic viral disease transmitted to humans either by domestic animals like dogs and cats or by wild animals like bats, skunks and raccoons. We present the case of a 25-year-old woman admitted due to behavioral disorders, generalized paresthesiasand acute respiratory deterioration compatible with a respiratory distres
Rev. Inst. Med. trop. S. Paulo. Publicado em: 17/01/2020
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2. Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures
Abstract Background: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondary damage implicated in many neurological disorders. Current
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 16/05/2019
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3. Central nervous system and analgesic profiles of Lippia genus
Abstract Many people use medicinal plants to relieve disorders related to the central nervous system, such as depression, epilepsy, anxiety and pain, even though the effectiveness of most of them has not yet been proven through scientific studies. Plants of the Lippia genus, Verbenaceae, are widely used in ethnobotany as a food, for seasoning and in antisept
Rev. bras. farmacogn.. Publicado em: 2019-02
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4. Spontaneous poisoning by Ricinus communis leaves (Euphorbiaceae) in goats
RESUMO: O objetivo deste estudo foi relatar os aspectos clínicos e patológicos de um surto de intoxicação pelas folhas de Ricinus communis em um rebanho de caprinos em Pernambuco, Nordeste do Brasil. Três a cinco horas após a ingestão dos brotos e arbustos jovens da planta, vinte cabras da raça Toggenburg e dois machos mestiços apresentaram quadro c
Pesq. Vet. Bras.. Publicado em: 2019-02
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5. The putative catalytic role of higher serotonin bioavailability in the clinical response to exposure and response prevention in obsessive-compulsive disorder
Objective: Exposure and response prevention (ERP) is effective to treat obsessive-compulsive disorder (OCD), but the lack of tolerance to the aversion nature of exposure techniques results in a high drop-out rate. There have been reports of a generic stress endurance effect of serotonin (5-HT) in the central nervous system (CNS) which might be explained by
Rev. Bras. Psiquiatr.. Publicado em: 17/10/2016
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6. Are astrocytes executive cells within the central nervous system?
ABSTRACT Experimental evidence suggests that astrocytes play a crucial role in the physiology of the central nervous system (CNS) by modulating synaptic activity and plasticity. Based on what is currently known we postulate that astrocytes are fundamental, along with neurons, for the information processing that takes place within the CNS. On the other hand,
Arq. Neuro-Psiquiatr.. Publicado em: 2016-08
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7. Constituintes químicos das cascas do caule de Vochysia thyrsoidea Pohl. (Vochysiaceae) e avaliação das atividades citotóxica e inibitória frente as catepsinas B e K
A new flavonoid, catechin-3-O-(3"-O-trans-cinnamoyl)-α-rhamnopyranoside, along with known compounds, catechin-3-O-α-rhamnopyranoside, 3-oxo-urs-12-en-28-oic acid, 2,4,6-trimethoxybenzoic acid, 2-butyl-D-fructofuranoside and 1-butyl-D-fructofuranoside, has been isolated from the stem bark of V. thyrsoidea. These compounds were assayed for inhibition of prot
Quím. Nova. Publicado em: 2014-04
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8. Structure-activity relationship study of rutaecarpine analogous active against central nervous system cancer
Com o objetivo de relacionar os descritores geométricos e eletrônicos dos derivados análogos da rutaercarpina com a atividade biológica contra o câncer do sistema nervoso central (CNS), cálculos de química quântica molecular em nível B3LYP/6-31(d) e análise estatística foram realizados para os 21 derivados análogos da rutaecarpina. Dos 86 descrit
J. Braz. Chem. Soc.. Publicado em: 28/01/2013
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9. Estudo químico de Sinningia allagophylla guiado por testes de atividade antiproliferativa
Activity guided fractionation of Sinningia allagophylla (Mart.) Wiehler ethanolic extract yielded a new benzochromene 8-methoxylapachenol, besides seven known compounds: lapachenol, sitosteryl oleate, sitosteryl linoleate, stigmasteryl oleate, stigmasteryl linoleate, dunniol and tectoquinone. Extract, fractions, and compounds lapachenol, 8-methoxylapachenol,
Química Nova. Publicado em: 2012
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10. Deficiência de tiamina e isolamento social afetam aspectos do comportamento motor e níveis centrais de GABA e glutamato
The main phenomenon approached in this study is the motor behavior, evaluated after two different types of environmental stimuli, the consumption of diet deficient in B1 vitamin and/or social isolation. The B1 vitamin, thiamine, is an essential nutrient for the nervous tissue. In previous studies, our research group has shown that the maternal thiamine defic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2011
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11. Avaliação da atividade tipo ansiolítica do óleo essencial das folhas de Spiranthera odoratissima A. St. Hil. - possível mecanismo envolvido / Anxiolytic-like activity of essential oil from Spiranthera odoratissima A. St. Hil. leaves possible mechanism evolved
Anxiety is among the most common chronic disease in the world. In Brasília city (capital of Brazil), anxiety disorders affect 12.1 % of population and are the most prevalent psychiatry disease. Since the introduction of benzodiazepines in the 1960s, they have been the most commonly prescribed treatment for anxiety disorders. However, their side-effects such
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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12. Bioassay-guided evaluation of central nervous system effects of citronellal in rodents
The central nervous system (CNS) depressant and anticonvulsant activities of citronellal (CT) were investigated in animal models. The CT in doses of 100, 200 and 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group. The highest dose of CT significantly reduced the remaini
Revista Brasileira de Farmacognosia. Publicado em: 08/07/2011