Clozapine
Mostrando 1-12 de 67 artigos, teses e dissertações.
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1. Clozapine prescription trends in Brazil in the last decade
Objective: Clozapine is a second-generation antipsychotic indicated for treatment-resistant schizophrenia. Studies in several countries have shown a low rate of clozapine use despite the fact that approximately 30% of schizophrenia cases are treatment-resistant. In Brazil, few studies have addressed the frequency and variety of antipsychotic use in individua
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Risk of neutropenia among clozapine users and non-users: results from 5,847 patients
Objective: Clozapine is underprescribed due to neutropenia risk. Blood tests every 3 months in those on continuous treatment for > 1 year who have never had an absolute neutrophil count (ANC) < 2,000/µL has been proposed as a monitoring strategy; however, there are no South American data to support this recommendation. This study sought to investigate wheth
Brazilian Journal of Psychiatry. Publicado em: 2022
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3. Promoting safer clozapine dosing in the Americas
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Health-related quality of life in patients treated with atypical antipsychotics
Objective: To assess health-related quality of life and associated factors in patients treated with atypical antipsychotics, as well as to determine utility values using the EuroQol-5D-3L instrument. Methods: A cross-sectional study was conducted at a state-run pharmacy in the Brazilian National Health System. Individuals were included if they were using a
Braz. J. Psychiatry. Publicado em: 2020-12
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5. Complex drug interaction of carbamazepine, fluvoxamine and clozapine in a patient with bipolar depression
Arch. Clin. Psychiatry (São Paulo). Publicado em: 28/11/2019
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6. Positive response to clozapine augmentation in a patient with obsessive-compulsive disorder complicated by a tardive movement disorder
Rev. Bras. Psiquiatr.. Publicado em: 2018-06
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7. The effect of obsessive compulsive symptoms on psychopathology in patients with schizophrenia
Abstract Background: There is a growing interest on the impact of comorbid obsessive-compulsive symptoms (OCS) on the course and severity of schizophrenia in recent years. Objective: This study determined the prevalence of OCS in schizophrenia patients and the clinical outcomes of the comorbidity. Methods: A total of 220 schizophrenia patients were recrui
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2018-05
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8. Olfactory deficit as a result of clozapine withdrawal syndrome in an animal model of schizophrenia: preliminary results
ABSTRACT Clozapine is an antipsychotic that produces serious withdrawal effects in schizophrenic patients. Olfactory deficits are well known as part of negative symptoms, but it is not known whether antipsychotic use and/or withdrawal are implicated. Then, we tested clozapine withdrawal in association with two widely used schizophrenia models: Neonatal immun
An. Acad. Bras. Ciênc.. Publicado em: 2018-04
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9. Severe orthostatic hypotension after adding low-dose aripiprazole to clozapine
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2017-06
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10. Efficacy of electroconvulsive therapy augmentation for partial response to clozapine: a pilot randomized ECT – sham controlled trial
Abstract Background Thirty percent of schizophrenia patients are treatment-resistant. Objective This is a single-blinded sham-controlled trial to assess the efficacy of electroconvulsive therapy (ECT) as augmentation strategy in patients with clozapine-resistant schizophrenia. Methods Twenty three subjects were randomly assigned to 12 sessions of ECT (
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2017-04
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11. Clozapine-induced esophagitis at therapeutic dose: a case report
Rev. Bras. Psiquiatr.. Publicado em: 2016-06
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12. Patterns of clozapine and other antipsychotics prescriptions in patients with treatment-resistant schizophrenia in community mental health centers in São Paulo, Brazil
Abstract Background Despite of its global underuse, clozapine is still the golden standard antipsychotic for patients with treatment-resistant schizophrenia (TRS). Objective To evaluate the patterns of clozapine and other antipsychotic drugs prescription in TRS in community mental health centers in São Paulo, Brazil. Methods A multiple-choice question
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2015-12