Clonality
Mostrando 13-24 de 165 artigos, teses e dissertações.
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13. Identification of clonally rearranged T-cell receptor beta chain genes in HTLV-I carriers as a potential instrument for early detection of neoplasia
We analyzed the genetic recombination pattern of the T-cell receptor beta-chain gene (TCR-beta) in order to identify clonal expansion of T-lymphocytes in 17 human T-lymphotropic virus type I (HTLV-I)-positive healthy carriers, 7 of them with abnormal features in the peripheral blood lymphocytes. Monoclonal or oligoclonal expansion of T-cells was detected in
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-05
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14. Emergence of new clone of Neisseria meningitidis Serogroup C in Grande São Paulo, 1990 a 2003 / Descrição de um novo clone de Neisseria meningitidis Sorogrupo C, Grande São Paulo, 1990 a 2003
Neisseria meningitidis (Men) is an important cause of morbidity and mortality and is a leading cause of bacterial meningitis and septicemia in children and young adults in Brazil. Meningococcal disease caused by MenC started becoming the most prevalent serogroup in 2001, representing 62.7% of all MD cases serogrouped in 2003 in Greater Sao Paulo and approxim
Publicado em: 2005
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15. Isoenzyme profiles of Trypanosoma cruzi stocks from different areas of Paraguay
Twenty one Trypanosoma cruzi stocks from humans, domiciliary triatomines and one sylvatic animal of different areas of Paraguay were subjected to isoenzyme analysis. Thirteen enzyme systems (15 loci in total) were studied. MN cl2 (clonets 39) and SO34 cl4 (clonets 20) were used as references. Relationships between stocks were depicted by an UPGMA dendrogram
Memórias do Instituto Oswaldo Cruz. Publicado em: 2001-05
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16. Theoretical Population Genetics of Repeated Genes Forming a Multigene Family
The evolution of repeated genes forming a multigene family in a finite population is studied with special reference to the probability of gene identity, i.e., the identity probability of two gene units chosen from the gene family. This quantity is called clonality and is defined as the sum of squares of the frequencies of gene lineages in the family. The mul
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17. T-cell receptor gene rearrangements as markers of lineage and clonality in T-cell neoplasms.
Ig gene rearrangements represent markers of lineage, clonality, and differentiation of B cells, allowing a molecular diagnosis and immunogenotypic classification of B-cell neoplasms. We sought to apply a similar approach to the study of T-cell populations by analyzing rearrangements of the T-cell receptor beta-chain (T beta) gene. Our analysis, by Southern b
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18. Molecular analysis of clonality in Kaposi's sarcoma.
BACKGROUND: Kaposi's sarcoma is considered to be an angioproliferative disease associated with a novel herpesvirus (KSHV/HHV8), but the precise pathophysiology of the lesion remains unclear. The study of clonality in Kaposi's sarcoma using X linked DNA polymorphism has been difficult so far, because of a very strong prevalence of the disease in males. AIMS:
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19. Rapid determination of clonality by detection of two closely-linked X chromosome exonic polymorphisms using allele-specific PCR.
We reported two specific, reproducible, and quantitative clonality assays based on detection of exonic polymorphisms of the X chromosome genes p55 and G6PD using rtPCR-LDR. These assays are inconvenient for screening purposes. This study sought to develop a simple, reproducible assay, practical for screening genomic DNA samples for p55/G6PD genotypes, rapid
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20. Assessment of clonality in gastrointestinal cancer by DNA fingerprinting.
DNA fingerprinting with three different probes (33.15, 33.6, and alpha-globin 3'HVR) was investigated as a method for the determination of clonality in gastrointestinal tumors. In 29/44 carcinomas the tumor DNA showed clonal somatic mutations that were not seen in the corresponding peripheral blood and normal mucosa samples. The changes consisted of either n
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21. Bacillus anthracis Virulence in Guinea Pigs Vaccinated with Anthrax Vaccine Adsorbed Is Linked to Plasmid Quantities and Clonality
Bacillus anthracis is a bacterial pathogen of great importance, both historically and in the present. This study presents data collected from several investigations and indicates that B. anthracis virulence is associated with the clonality and virulence of plasmids pXO1 and pXO2. Guinea pigs vaccinated with Anthrax Vaccine Adsorbed were challenged with 20 B.
American Society for Microbiology.
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22. The importance of clonality - Langerhans' cell histiocytosis
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23. Methylation analysis by means of PCR SSCP: application to clonality studies.
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24. Studies on clonality by PCR analysis of the PGK-1 gene.